Bile salt deconjugation activity of Propionibacterium strains and their cholesterol co-precipitation abilities

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Küçük Resim

Tarih

2019

Dergi Başlığı

Dergi ISSN

Cilt Başlığı

Yayıncı

Blackwell Publishing

Erişim Hakkı

info:eu-repo/semantics/closedAccess

Özet

The present study investigated the deconjugation of bile salts and co-precipitation of cholesterol with deconjugated bile salts by seven Propionibacterium spp. strains in vitro. Propionibacterium spp. could deconjugate sodium glycocholate (1.53–5.31 mM) and sodium taurocholate (0.08–0.25 mM) bile salts. The highest cholesterol precipitation (47.8 µg/mL) was determined with Propionibacterium freudenreichii subsp. freudenreichii SP3 strain in a 0.15% oxgall-containing medium. Significant (P < 0.05) correlations were observed between cholesterol co-precipitation and deconjugation of sodium glycocholate among the strains. In vitro bile salt deconjugation activity studies of P. freudenreichii subsp. freudenreichii SP3 strain revealed that this strain may have potential as a probiotic strain for deconjugation of bile salts in vivo studies. © 2019 Society of Dairy Technology

Açıklama

Anahtar Kelimeler

Bile Salt, Co-Precipitation, Deconjugation, Probiotics, Propionibacterium

Kaynak

International Journal of Dairy Technology

WoS Q Değeri

N/A

Scopus Q Değeri

Q1

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