Evaluation of the relationship between rosacea cutaneous subtype and meibography findings

dc.authorid0000-0003-3504-9886
dc.authorid0000-0003-3129-0269
dc.authorid0000-0001-5129-9397
dc.authorid0000-0003-2965-481X
dc.authorid0000-0002-8480-4561
dc.contributor.authorKemeriz, Funda
dc.contributor.authorErdal Çalıkoğlu, Emel
dc.contributor.authorYaşar, Erdoğan
dc.contributor.authorGürlevik, Uğur
dc.contributor.authorAksoy Saraç, Gülhan
dc.date.accessioned2022-12-26T08:16:09Z
dc.date.available2022-12-26T08:16:09Z
dc.date.issued2022
dc.departmentTıp Fakültesi
dc.description.abstractAcne rosacea (AR) is a chronic inflammatory skin disease that can cause serious ocular complications. This study was designed to evaluate dry eye disease (DED) and meibomian gland dysfunction (MGD) in AR patients and to investigate the relationship between the cutaneous subtype of AR and ocular involvement. Materials and Methods: This study included 67 participants with AR and 50 healthy individuals. Patients diagnosed with 3 cutaneous subtypes were examined: erythematotelangiectatic rosacea (ETR), papulopustular rosacea (PPR), and phymatous rosacea (PR). An ophthalmatological examination was performed that included an evaluation of lid margin alterations due to meibomian gland (MG) obstruction, Ocular Surface Disease Index assessment, tear film break-up time testing, Schirmer testing, and a corneal conjunctival fluorescein staining assessment. Meibography was used to evaluate the upper and lower lids for MG loss. Results: Findings in the AR group revealed MGD in 45.5% and DED in 28.1%. The meibomian gland loss rate (MGLR) was 38.7±16.9% and the meibomian gland loss grade (MGLG) was 1.57±0.82%. The rate of MGLR and MGLG was significantly greater in the AR group than in the control group (p<0.001). PPR was seen in 59.7% of the 67 patients, ETR in 29.9%, and PR in 13.4%. A comparison of the MGD, MGLR, MGLG, and presence of DED in the 3 cutaneous subtype groups yielded statistically insignificant results. Conclusion: AR can affect MG morphology, which may result in MGD or DED. Though we did not find a significant difference in the ocular findings by subgroup, ocular involvement is a recognized risk in AR. Ophthalmologists and dermatologists should cooperate in the evaluation of AR patients. Additional studies to further examine the effects in subtype groups are recommended.
dc.identifier.doi10.14744/etd.2021.62343
dc.identifier.endpage386en_US
dc.identifier.issue4en_US
dc.identifier.startpage382en_US
dc.identifier.urihttps:/dx.doi.org/10.14744/etd.2021.62343
dc.identifier.urihttps://hdl.handle.net/20.500.12451/9726
dc.identifier.volume44en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherKare Yayıncılık, Ali Cangül
dc.relation.ispartofErciyes Medical Journal
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectDry Eye Disease
dc.subjectMeibography
dc.subjectMeibomian Gland Dysfunction
dc.subjectOcular Surface Diseases
dc.subjectRosacea
dc.titleEvaluation of the relationship between rosacea cutaneous subtype and meibography findings
dc.typeArticle

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