Comparison of the effects of Autologous Cytokine-rich Serum (ACRS) and Platelet-Rich Plasma (PRP) on skin wound healing

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dc.authorid0000-0001-8140-3108
dc.authorid0000-0001-6050-6765
dc.authorid0000-0003-2267-1238
dc.authorid0000-0001-5949-4752
dc.authorid0000-0001-8970-7763
dc.authorid0000-0002-2778-8059
dc.contributor.authorErol, Hanifi
dc.contributor.authorKarakaş, Erol
dc.contributor.authorErmiş, Mustafa
dc.contributor.authorAkçakavak, Gökhan
dc.contributor.authorAslan, Nevzat Emre
dc.contributor.authorKarataş, Özhan
dc.date.accessioned2025-07-10T08:31:53Z
dc.date.available2025-07-10T08:31:53Z
dc.date.issued2025
dc.departmentVeteriner Fakültesi
dc.description.abstractWound healing is one of the most complex biological events, involving physiological processes such as tissue restoration and intricate cellular and molecular activities. The aim of this study was to investigate the effects of Autologous Cytokine Rich Serum (ACRS) and Platelet-rich plasma (PRP) on wound healing and to compare their impact on tissue repair using histopathological and immunohistochemical methods. A total of 42 healthy Wistar-Albino rats were used as material. The histopathological and immunohistochemical evaluations showed that ACRS is more effective than PRP on wound healing. The superior efficacy of ACRS is attributed to its stimulation of anti-inflammatory cytokines and provision of essential nutrients such as amino acids, vitamins, and lipids. Further detailed studies are recommended to explore these findings.
dc.identifier.doi10.2478/acve-2025-0013
dc.identifier.endpage165
dc.identifier.issn05678315
dc.identifier.issue2
dc.identifier.scopus105009106331
dc.identifier.startpage151
dc.identifier.urihttps://dx.doi.org/10.2478/acve-2025-0013
dc.identifier.urihttps://hdl.handle.net/20.500.12451/13234
dc.identifier.volume75
dc.identifier.wosWOS:001512847900003
dc.identifier.wosqualityQ3
dc.indekslendigikaynakScopus
dc.indekslendigikaynakWeb of Science
dc.institutionauthorAkçakavak, Gökhan
dc.institutionauthorid0000-0001-5949-4752
dc.language.isoen
dc.publisherSciendo
dc.relation.ispartofActa Veterinaria
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectACRS
dc.subjectPRP
dc.subjectRat
dc.subjectWound
dc.titleComparison of the effects of Autologous Cytokine-rich Serum (ACRS) and Platelet-Rich Plasma (PRP) on skin wound healing
dc.typeArticle

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