In vitro antioxidant and antimicrobial activities of aerial parts of Algerian Jurinea humilis DC (Asteraceae)

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dc.contributor.authorAyad, Radia
dc.contributor.authorÇakmak, Yavuz S.
dc.contributor.authorÖzüsağlam, Meltem A.
dc.contributor.authorMedjroubi, Kamel
dc.contributor.authorAkkal, Salah
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-16T09:17:41Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-16T09:17:41Z
dc.date.issued2017
dc.departmentSabire Yazıcı Fen Edebiyat Fakültesi
dc.description.abstractPurpose: To assess the polyphenolic composition of various solvent extracts of Jurinea humilis DC. as well as their in vitro biological effects. Methods: The crude extracts of the aerial parts of Jurinea humilis were obtained by maceration method with dichloromethane (DCM), methanol (MeOH) and ethyl acetate (EtoAC), separately. Folin-Ciocalteu and aluminum chloride procedures were used to quantify the total phenolic and flavonoid contents, respectively, while antioxidant properties were determined by two methods: phosphomolybdenum and DPPH assays. Antimicrobial activity was also evaluated by disc diffusion method. Results: The ethyl acetate extract exhibited the highest amount of total phenolic content (TPC, 169.14 +/- 7.22 mg gallic acid equivalent/g sample) and total flavoniod contents (TFC, 104.91 +/- 0.22 mg rutin equivalent/g sample). The extract (EtoAC) also showed the strongest antioxidant activity of the three extracts, especially DPPH assay (IC50 = 0.16 +/- 0.00 mg/mL), as well as demonstrated the highest activity against the pathogenic strains tested. Conclusion: The results suggest that J. humilis DC. is rich in phenolic and flavonoid contents which may be responsible for good antioxidant and antimicrobial properties. Thus, J. humilis may be a promising source of new antioxidant agents and pharmaceuticals.
dc.description.sponsorshipMinistry of Higher Education and Scientific Research of Algeria [E0021040099]
dc.description.sponsorshipThis study was supported by Ministry of Higher Education and Scientific Research of Algeria (grant no. CNEPRU No E0021040099).
dc.identifier.doi10.4314/tjpr.v16i12.14
dc.identifier.endpage2909en_US
dc.identifier.issn1596-5996
dc.identifier.issue12en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage2903en_US
dc.identifier.urihttps://doi.org/10.4314/tjpr.v16i12.14
dc.identifier.urihttps://hdl.handle.net/20.500.12451/4782
dc.identifier.volume16en_US
dc.identifier.wosWOS:000426761700013
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherPharmacotherapy Group
dc.relation.ispartofTropical Journal of Pharmaceutical Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectJurinea Humilis
dc.subjectPhenolic
dc.subjectFlavonoid
dc.subjectAntioxidant
dc.subjectAntimicrobial
dc.titleIn vitro antioxidant and antimicrobial activities of aerial parts of Algerian Jurinea humilis DC (Asteraceae)
dc.typeArticle

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