The prognostic value of C-reactive protein/albumin ratio in acute mesenteric Ischemia

dc.authorid0000-0002-9653-7958
dc.contributor.authorKaçer, İlker
dc.contributor.authorÇağlar, Ahmet
dc.contributor.authorAkıllı, Nazire Belgin
dc.date.accessioned2022-02-25T06:02:07Z
dc.date.available2022-02-25T06:02:07Z
dc.date.issued2023
dc.departmentTıp Fakültesi
dc.description.abstractDiagnosis of acute mesenteric ischemia (AMI) in its early stages is important for reversing ischemic damage. The CRP to albumin (CRP/Alb) ratio has been defined as an inflammatory indicator and is associated with the severity of inflammation and mortality rates. However, the prognostic value of CRP/Alb has not been evaluated in patients with AMI. Here, we aimed to examine the prognostic significance of CRP/Alb and compare it with other inflammatory markers. Materials and Methods: In this retrospective, case-control study, we included patients diagnosed with AMI at the emergency department between January 1, 2016, and December 31, 2020. In addition to demographic characteristics, lactate, D-dimer, white blood cell (WBC), CRP/Alb, and neutrophil/lymphocyte ratio (NLR) were recorded. Testing characteristics of CRP/Alb in predicting in-hospital mortality were studied. Results: The mean age of 132 patients was 66.48 ± 15.95 years and 71 (53.8%) of them were male. The cut-off value obtained using the receiver operating characteristic (ROC) curve for in-hospital mortality was a CRP/Alb ratio of >1.32 (sensitivity, 93.65%; specificity, 69.57%; +LR, 3.08; ?LR,.091; AUC,.782; 95% CI,.70-.85; P <.0001). The comparison of ROC curves between CRP/Alb and WBC, NLR, and lactate revealed a statistically significant difference (P <.05), whereas there was not any statistically significant difference between the ROC curves of CRP/Alb and D-dimer (P =.47). Conclusion: C-reactive protein/albumin ratio is a powerful predictor of in-hospital mortality for AMI patients. It was superior to WBC, NLR, and lactate. It could be used to determine low-risk patients and help clinicians with treatment options.
dc.identifier.doi10.1177/00031348221074220
dc.identifier.endpage-en_US
dc.identifier.issn0003-1348
dc.identifier.issue-en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage-en_US
dc.identifier.urihttps:/dx.doi.org/10.1177/00031348221074220
dc.identifier.urihttps://hdl.handle.net/20.500.12451/9229
dc.identifier.volume-en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSAGE Publications Inc.
dc.relation.ispartofAmerican Surgeon
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAcute Mesenteric Ischemia
dc.subjectAlbumin
dc.subjectC-reactive Protein
dc.subjectD-dimer
dc.subjectNeutrophil/lymphocyte Ratio
dc.subjectIn-hospital Mortality
dc.titleThe prognostic value of C-reactive protein/albumin ratio in acute mesenteric Ischemia
dc.typeArticle

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