Effect of fasting on choroidal thickness and Its diurnal variation

dc.authorid0000-0003-2544-3580
dc.authorid0000-0002-8249-2621
dc.authorid0000-0003-4468-3985
dc.contributor.authorUyar, Enes
dc.contributor.authorDoğan, Ümit
dc.contributor.authorUlaş, Fatih
dc.contributor.authorÇelebi, Serdal
dc.date.accessioned2022-05-20T05:12:16Z
dc.date.available2022-05-20T05:12:16Z
dc.date.issued2019
dc.departmentTıp Fakültesi
dc.description.abstractThe aim of this study was to assess the effect of Ramadan fasting on choroidal thickness (CT) and its associated diurnal variations using spectral domain optic coherence tomography. Materials and Methods: Ocular measurements were performed on a single eye of 87 healthy individuals. Eyes were evaluated twice a day around 8.00 a.m. and 4.00 p.m. during Ramadan. Evaluations were repeated at the same time of the day, 1 month following Ramadan on the same subjects. Measurements of choroidal and retinal thickness were performed at central, temporal and nasal segments. Results: The comparison of measurements revealed that temporal CT at 8.00 a.m. and foveal, temporal and nasal CTs at 4.00 p.m. were significantly reduced during fasting (p values were 0.005, <0.001, 0.001 and 0.046, respectively). Mean changes of CTs during fasting were 14.76 ± 16.01, 9.90 ± 19.57 and 8.10 ± 16.81 µm at the fovea, temporal and nasal segments, respectively. However, CTs at non-fasting conditions were measured as 6.13 ± 12.93, 3.78 ± 15.23 and 5.05 ± 13.60 µm, respectively. In comparison, diurnal variations of foveal and temporal CTs during fasting were significantly higher than the controls (p values were <0.001 and 0.004, respectively). Additionally, retinal thicknesses during fasting were significantly reduced compared to the controls in all segments measured at 4.00 p.m. (p for all values <0.05) Conclusions: The results of the present study revealed that fasting and dehydration caused a reduction of the choroidal and retinal thicknesses. Likewise, they are also responsible for the increased diurnal variation of CTs. Therefore, early hours of the day may be preferred to evaluate retinal and choroidal thicknesses during Ramadan to avoid the effects of dehydration on the measurement results.
dc.identifier.doi10.1080/02713683.2019.1584677
dc.identifier.endpage700en_US
dc.identifier.issn0271-3683
dc.identifier.issue7en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage695en_US
dc.identifier.urihttps:/dx.doi.org/10.1080/02713683.2019.1584677
dc.identifier.urihttps://hdl.handle.net/20.500.12451/9404
dc.identifier.volume44en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherTaylor and Francis Ltd
dc.relation.ispartofCurrent Eye Research
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/embargoedAccess
dc.subjectChoroidal Thickness
dc.subjectDiurnal Variation
dc.subjectFasting
dc.subjectOptic Coherence Tomography
dc.subjectRetinal Thickness
dc.titleEffect of fasting on choroidal thickness and Its diurnal variation
dc.typeArticle

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