The impact of treatment with continuous positive airway pressure on acute carbon monoxide poisoning

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dc.contributor.authorÇağlar, Bahadır
dc.contributor.authorSerin, Süha
dc.contributor.authorYılmaz, Gökhan
dc.contributor.authorTorun, Alper
dc.contributor.authorParlak, İsmet
dc.date.accessioned2019-11-08T11:17:50Z
dc.date.available2019-11-08T11:17:50Z
dc.date.issued2019
dc.departmentTıp Fakültesi
dc.description*Parlak, İsmet ( Aksaray, Yazar )
dc.description.abstractIntroduction:Approximately 50,000 patients per year present at emergency departments (EDs) because of carbon monoxide (CO) intoxication. The hypothesis of this study was that the half-life of CO and the regression period of complaints could be reduced more rapidly by applying oxygen with the Continuous Positive Airway Pressure (CPAP) modality using a non-invasive mechanical ventilator.Methods:The patients were divided into Group 1 and Group 2 in terms of the treatment method applied. Patients in Group 1 received FiO2 1.0 15 l/minute oxygen at room temperature for at least 30 minutes with a non-rebreather mask. Patients in Group 2 received FiO2 1.0 oxygen at 12 cmH2O pressure with non-invasive mechanical ventilation for at least 30 minutes with an oronasal mask in the CPAP modality.Results:The median values (interquartile range) of carboxyhemoglobin (COHb) levels at zero and 30 minutes of patients were 19% (8) and 14% (6) in Group 1 and 22% (8) and nine percent (3) in Group 2; a median difference of six percent (2) was detected in Group 1 and of 13% (4) in Group 2 in the first 30 minutes (P <.001). When the symptoms of the patients were examined, the median values of Group 1 and Group 2 at zero minutes were both eight units and at 30 minutes were five and three units, respectively. A decrease of five units was determined in the median of Group 2 in the first 30 minutes, and a decrease of two units in the median of Group 1 (P <.001).Conclusion:The use of CPAP was determined to more rapidly reduce COHb level as opposed to high-flow oxygen therapy. It is also thought that it may enable earlier discharge by reducing the duration of the emergency follow-up since it provides a faster improvement in the symptoms of the patients.
dc.description.abstract...
dc.identifier.doi10.1017/S1049023X19005028
dc.identifier.endpage-en_US
dc.identifier.issn1049-023X
dc.identifier.issue-en_US
dc.identifier.scopusqualityQ1
dc.identifier.startpage-en_US
dc.identifier.urihttps://dx.doi.org/10.1017/S1049023X19005028
dc.identifier.urihttps://hdl.handle.net/20.500.12451/6983
dc.identifier.volume-en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherCambridge University Press
dc.relation.ispartofPrehospital and Disaster Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectCarbon Monoxide Poisoning
dc.subjectNon-invasive Ventilation
dc.subjectToxicology
dc.titleThe impact of treatment with continuous positive airway pressure on acute carbon monoxide poisoning
dc.typeArticle

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