Phenolic compounds, antioxidant properties and enzyme inhibition ability of adiantum capillus veneris L. linked to alzheimer's disease, diabetes mellitus and skin disorders

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dc.authoridZengin, Gokhan -- 0000-0001-6548-7823
dc.contributor.authorAbdulqadir, Ako
dc.contributor.authorÇakmak, Yavuz Selim
dc.contributor.authorZengin, Gökhan
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-16T09:17:15Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-16T09:17:15Z
dc.date.issued2018
dc.departmentSabire Yazıcı Fen Edebiyat Fakültesi
dc.description.abstractAdiantum capillus-veneris L. is one of the best ferns that are used in traditional medicine for breaking kidney stones. This study aimed to evaluate antioxidant activity of the different extracts of A. capillus-veneris using the phosphomolybdenum assay, free radical scavenging activity (DPPH), ferric reducing antioxidant power (FRAP), and cupric ion reducing power activity test (CUPRAC). Besides, the enzyme inhibition activities were determined against acetylcholinesterase, tyrosinase, alpha-glucosidase and alpha-amylase. Total and individual phenolic compounds were also determined by spectrophotometric and HPLC methods, respectively. Total phenolic and flavonoid contents were found to change between 354-441 mg GAE/g and 23-123 mg QE/g, respectively. The major phenolic compounds were benzoic acid, epicatechin, syringic acid and catechin. Methanol and ethyl acetate extracts exhibited stronger antioxidant abilities compared to water extract. A. capillus-veneris extracts showed high enzyme inhibition activities except for butrylcholinesterase. The results indicated that the different extracts of A. capillus-veneris L. can be used as natural sources of antioxidants and enzyme inhibitors.
dc.identifier.doi10.2174/1385272822666180711145256
dc.identifier.endpage1703en_US
dc.identifier.issn1385-2728
dc.identifier.issn1875-5348
dc.identifier.issue17en_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage1697en_US
dc.identifier.urihttps://doi.org/10.2174/1385272822666180711145256
dc.identifier.urihttps://hdl.handle.net/20.500.12451/4722
dc.identifier.volume22en_US
dc.identifier.wosWOS:000447281500005
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherBentham Science Publishers B.V.
dc.relation.ispartofCurrent Organic Chemistry
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectAdiantum Capillus-Veneris L.
dc.subjectBiological Activities
dc.subjectDiabetes
dc.subjectAlzheimer
dc.subjectSkin Disorders
dc.subjectDiabetes Mellitus
dc.titlePhenolic compounds, antioxidant properties and enzyme inhibition ability of adiantum capillus veneris L. linked to alzheimer's disease, diabetes mellitus and skin disorders
dc.typeArticle

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