How reliable is the statistical evaluation using the 'mean' in an abnormally distributed dataset
| dc.authorid | 0000-0002-1743-8194 | |
| dc.authorid | 0000-0003-2286-4398 | |
| dc.authorid | 0000-0003-3432-7901 | |
| dc.contributor.author | Ayşe Tandırcoğlu, Ümit | |
| dc.contributor.author | Ateş, Can | |
| dc.contributor.author | Alan, Serdar | |
| dc.date.accessioned | 2024-05-08T06:05:45Z | |
| dc.date.available | 2024-05-08T06:05:45Z | |
| dc.date.issued | 2024 | |
| dc.department | Tıp Fakültesi | |
| dc.description.abstract | We read with great interest the article by Tourneux et al. [1] regarding the predictors of continuous positive airway pressure (CPAP) failure in moderate-to-late preterm infants. CPAP failure, requiring mechanical ventilation or surfactant administration, was detected in 12% of their study group. They reported that the strongest factor associated with CPAP failure was a low cut-off of 23% fraction inspired of oxygen (FiO2) at 3 h of life, which was significantly lower than in previous studies (29%) [1]. There is a major concern about the main outcome of this study, the difference in maximum FiO2 values between CPAP failure and CPAP success groups at 3 h after birth. The lowest value of FiO2 is estimated as 18.6% and 18.5% in the CPAP success and CPAP failure groups, respectively, if the authors gave the mean and standard deviation (mean±SD) of maximum FiO2 values (22.7±4.1 for the CPAP success group and 34.4±15.9 for the CPAP failure group). FiO2 values below 21% cannot be administered in any scientific study performed on human newborns. FiO2 values that are not compatible with reality are a consequence of the abnormal distribution of the data in the study. Besides, the authors have already stated the lowest FiO2 value as 22% in their supplementary data. | |
| dc.identifier.doi | 10.1007/s00431-023-05346-w. | |
| dc.identifier.endpage | 978 | en_US |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.scopusquality | Q1 | |
| dc.identifier.startpage | 977 | en_US |
| dc.identifier.uri | https:/dx.doi.org10.1007/s00431-023-05346-w. | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/11794 | |
| dc.identifier.volume | 183 | en_US |
| dc.indekslendigikaynak | Scopus | |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | SpringerLink | |
| dc.relation.ispartof | European Journal of Pediatrics | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/embargoedAccess | |
| dc.subject | Statistical Evaluation | |
| dc.subject | Distributed Dataset | |
| dc.title | How reliable is the statistical evaluation using the 'mean' in an abnormally distributed dataset | |
| dc.type | Article |
