Neutrophil-to-lymphocyte ratio predicts coronary artery lesion complexity and mortality after non-ST-segment elevation acute coronary syndrome

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dc.contributor.authorSoylu, Korhan
dc.contributor.authorGedikli, Ömer
dc.contributor.authorDağaşan, Göksel
dc.contributor.authorAydin, Ertan
dc.contributor.authorAksan, Gökhan
dc.contributor.authorNar, Gökay
dc.contributor.authorİnci, Sinan
dc.contributor.authorYılmaz, Özcan
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-16T08:22:05Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-16T08:22:05Z
dc.date.issued2015
dc.departmentTıp Fakültesi
dc.descriptionPubMed ID: 26164277
dc.description.abstractObjective Inflammatory mechanisms are known to play an important role in coronary artery disease. The present study aimed to investigate the importance of the neutrophil-to-lymphocyte ratio (NLR) in terms of in-hospital mortality and its association with currently used risk scores in patients with non-ST-elevation acute coronary syndrome (NSTE-ACS). Methods Three hundred and seventeen patients with NSTE-ACS were included. The patients were divided into tertiles according to their NLR values (NLR <2.6, NLR=2.6-4.5, and NLR >4.5). Clinical and angiographic risk was evaluated by the SYNTAX and GRACE risk scores. Results The GRACE risk score was significantly higher in the group with high NLR values compared to those with moderate or low NLR (161.5±40.3, 130.5±32.3, and 123.9±34.3, respectively, p<0.001). Similarly, the SYNTAX score was significantly higher in the group with high NLR values (20.4±10.1, 15.5±10.5, and 13.4±7.8, respectively, p=0.003). Moreover, both GRACE (r=0.457, p<0.001) and SYNTAX scores (r=0.253, p=0.001) showed a significant positive correlation with NLR. Conclusion NLR has been found to be correlated with clinical and angiographic risk scores. Low NLR might be a good predictor for low in-hospital mortality and simple coronary anatomy in NSTE-ACS patients. © 2014 Sociedade Portuguesa de Cardiologia.
dc.identifier.doi10.1016/j.repc.2015.01.013
dc.identifier.endpage471en_US
dc.identifier.issn0870-2551
dc.identifier.issue07.Augen_US
dc.identifier.scopusqualityQ3
dc.identifier.startpage465en_US
dc.identifier.urihttps://dx.doi.org/10.1016/j.repc.2015.01.013
dc.identifier.urihttps://hdl.handle.net/20.500.12451/2460
dc.identifier.volume34en_US
dc.indekslendigikaynakScopus
dc.indekslendigikaynakPubMed
dc.language.isoen
dc.publisherSociedade Portuguesa de Cardiologia
dc.relation.ispartofRevista Portuguesa de Cardiologia
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectGRACE score
dc.subjectNeutrophil-to-lymphocyte Ratio
dc.subjectNon-ST-segment Acute Coronary Syndrome
dc.subjectSYNTAX score
dc.titleNeutrophil-to-lymphocyte ratio predicts coronary artery lesion complexity and mortality after non-ST-segment elevation acute coronary syndrome
dc.typeArticle

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