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Evaluation of protective effects of quercetin against cypermethrin-induced lung toxicity in rats via oxidative stress, inflammation, apoptosis, autophagy, and endoplasmic reticulum stress pathway
(John Wiley and Sons Inc, 2022)
Cypermethrin (CYP), a type II synthetic pyrethroid, is the most widely used insecticide worldwide. Inhalation of it may cause side effects. This study is aimed to examine potential protection of quercetin (QUE) which is a ...
Effect of syringic acid on oxidative stress, autophagy, apoptosis, inflammation pathways against testicular damage induced by lead acetate.
(Elsevier GmbH, 2023)
Heavy metals are one of the environmental pollutants. Lead (Pb) is one of the most common of these heavy metals. In this study, it was aimed at investigating the effects of syringic acid (SA) against testicular toxicity ...
Protective effects of zingerone against sodium arsenite-induced lung toxicity: A multi-biomarker approach
(Mashhad University of Medical Sciences, 2023)
Sodium arsenite (SA) exposure is toxic to the body. Zingerone (ZNG) is a flavonoid with many biological properties found naturally in honey and plants. This study aimed to determine the effects of ZNG on SA-induced rat ...
Carvacrol protects against λ-Cyhalothrin-induced hepatotoxicity and nephrotoxicity by modulating oxidative stress, inflammation, apoptosis, endoplasmic reticulum stress, and autophagy
(John Wiley and Sons Inc, 2023)
λ-Cyhalothrin, a type II synthetic pyrethroid, has been widely used in households, agriculture, public health, and gardening to control insect pests. Despite its widespread usage, it is known to induce a variety of adverse ...
Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum stress
(Elsevier Inc., 2023)
Paclitaxel (PTX) is widely used to treat a number of malignancies, although it has toxic side effects. Hesperidin (HES) has a wide range of biological and pharmacological properties, including anti-inflammatory and antioxidant ...
Protective Effect of Morin Hydrate in Ischemia/Reperfusion Injury of Rat Skeletal Muscle
(Veteriner Hekimler Derneği, 2023)
Reaktif oksijen türlerinin neden olduğu hücre hasarı iskemi/reperfüzyon (I/R) hasarında temel etiyolojik faktör olarak kabul edilmektedir. Bu nedenle sunulan çalışmada morin’in iskelet kası I/R hasarındaki etkilerinin ...
Sıçanlarda İfosfamid ile Oluşturulmuş Mide Hasarında Morinin Etkilerinin Histopatolojik ve Biyokimyasal Olarak İncelenmesi
(Mustafa İSSİ, 2023)
Bu çalışmada, sıçanlarda deneysel ifosfamid (IFO) uygulamasının neden olduğu mide toksisitesi üzerine morinin (MOR) etkilerinin belirlenmesi amaçlandı. Bu amaçla deney hayvanları beş gruba (n=7) ayrıldı. Gruplar kontrol, ...
Morin provides therapeutic effect by attenuating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and oxidative DNA damage in testicular toxicity caused by ifosfamide in rats
(Mashhad : Mashhad University of Medical Sciences, 2023)
Objectives: In the present study, it was evaluated whether morin has a protective effect on testicular toxicity caused by ifosfamide (IFOS), which is used in the treatment of various malignancies.
Materials and methods: ...
Carvacrol Reduces Mercuric Chloride-Induced Testicular Toxicity by Regulating Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histopathological Changes
(Springer, 2023)
Mercuric chloride (HgCl2) is a heavy metal that is toxic to the human body. Carvacrol (CAR) is a flavonoid found naturally in plants and has many biological and pharmacological activities including anti-inflammatory, ...
Naringin protects against paclitaxel-induced toxicity in rat testicular tissues by regulating genes in pro-inflammatory cytokines, oxidative stress, apoptosis, and JNK/MAPK signaling pathways
(John Wiley and Sons Inc, 2024)
Paclitaxel (PTX), which is actively used in the treatment of many types of cancer, has a toxic effect by causing increased oxidative stress in testicular tissues. Naringin (NRG) is a natural flavonoid found in plants, and ...
