Browsing by Author "Eröz, Recep"
Now showing items 1-20 of 21
-
Ailesel Akdeniz Ateşi Hastalarının MEFV Gen Mutasyon Tiplerinin Sıklığı ve Hastalarda Gen Mutasyonu ile Klinik Bulgular Arasındaki ilişkilerin Değerlendirilmesi
Barış, Savaş; Yavaş, Cüneyd; Atan Uzun, Çiğdem; Kaya Akça, Ümmüşen; Doğan, Mustafa; Eröz, Recep (Cahfer GÜLOĞLU, 2023)Ailevi Akdeniz Ateşi (AAA) tekrarlayan ateş, peritonit, plörit, artrit veya erizipel benzeri cilt semptomları ile karakterize otozomal resesif olarak kalıtılan otoinflamatuar bir hastalıktır. Kliniğimize yukarıda bahsedilen ... -
Apoptosis-associated speck-like protein containing a CARD (ASC), TNF Like Factor 1a(TL-1a) and B Cell Chemoattractant Chemokine Ligand 13(CXCL-13) expression profiles in familial Mediterranean fever (FMF) patients
Kurt, Fatih; Eröz, Recep; Kocabay, Kenan (Düzce Üniversitesi, 2023)This study was carried out to compare the expression levels of ASC(Apoptosis Associated Speck Like Protein Containing a CARD), TL-1a(TNF Like Factor 1a) and CXCL 13(B Cell Chemoattractant Chemokine Ligand 13) genes in FMF ... -
Argyrophilic nucleolar organizer regions as a promising biomarker for the detection of brain hypoxia levels caused by different doses of carbon monoxide poisoning
Yeşildağ, Kerim; Kokulu, Kamil; Mutlu, Hüseyin; Eröz, Recep; Taha Sert, Ekrem; Sarıtaş, Ayhan (Academia Nacional de Medicina de México, 2021)The purpose of the study is to investigate whether there is any relationship between mean argyrophilic nucleolar organizing regions (AgNOR) number and total AgNOR area/total nuclear area (TAA/TNA) ratio and the levels of ... -
Argyrophilic nucleolar organizer regions as new biomarkers in ST-Elevation myocardial infarction
Damar, İbrahim Halil; Eröz, Recep (MDPI, 2022)(1) Background: ST-elevation myocardial infarction (STEMI) is an inflammatory disease in which neutrophils, macrophages, and lymphocytes accumulate in the ischemic myocardium and have important functions. Nucleolar-organizing ... -
Batı Ege Bölgesinde α-Talasemi Genotipleri ve α-Talasemi Genotip Frekansı
Barış, Savaş; Yavaş, Cüneyd; Balasar, Özgür; Gördü, Zülfükar; Doğan, Mustafa; Eröz, Recep (Düzce Üniversitesi, 2023)Yaygın görülen bir tek gen hastalığı olan Alfa talasemi, α-globin zincirinin kusurlu sentezi ile ortaya çıkar. Globin genlerindeki bozukluklara bağlı olarak çok geniş bir klinik spektruma yayılan bu hastalıkta çok sayıda ... -
Clinical and molecular findings in a turkish family who had a (c.869- 1G>A) splicing variant in PSEN1 gene with a rare condition: the variant alzheimer's disease with spastic paraparesis
Doğan, Mustafa; Eröz, Recep; Tecellioğlu, Mehmet; Gezdirici, Alper; Çevik, Betül; Barış, İbrahim (Bentham Science Publishers Ltd., 2022)Early-onset Alzheimer's disease (EOAD) is commonly diagnosed with an onset age of earlier than 65 years and accounts for 5-10% of all Alzheimer's disease (AD) cases. To date, although only 10-15% of familial EOAD cases ... -
Discovery of a novel homozygous SOD1 truncating variant bolsters infantile SOD1 deficiency syndrome
Doğan, Mustafa; Teralı, Kerem; Eröz, Recep; Kılıç, Hüseyin; Gezdirici, Alper; Gönüllü, Burçin (Springer Science and Business Media B.V., 2024)Superoxide dismutase 1 (SOD1) is an important antioxidant enzyme whose main function is to neutralise superoxide free radicals in the cytoplasm. Heterozygous variants in SOD1 are responsible for a substantial percentage ... -
Evaluation of both expression and serum protein levels of caspase-8 and mitogen-activated protein kinase 1 genes in patients with different severities of COVID-19 infection
Acat, Murat; Yıldız Gülhan, Pınar; Eröz, Recep; Ertınmaz Özkan, Ayşegül; Koca, Oğuzhan; Çınar, Caner (Springer Science and Business Media B.V., 2023)Aim: The current study aimed to evaluate the effects of caspase-8 (CASP8) and mitogen-activated protein kinase 1 (MAPK1) gene expression levels and their products on preventing severe acute respiratory syndrome coronavirus ... -
Evaluation of HLA-B51 frequency and its relationship with clinical findings in patients with Behcet's disease: 4-year analysis in a single center
Erdem Sultanoğlu, Tuba; Eröz, Recep; Ataoğlu, Safinaz (Springer Nature, 2023)The clinical findings of Behcet's disease (BD) differ according to the country and race investigated. The most important genetic factor known in the pathogenesis of BD is HLA-B51, and this positivity is high in countries ... -
The Evaluation of the Genetic Variation Types of the Uridine Diphosphate Glucuronosyl Transferase 1A1 Gene by Next-Generation Sequencing and Their Effects on Bilirubin Levels in Obese Children
Aslantaş, Merve; Kılıçaslan, Önder; Eröz, Recep; Kocabay, Kenan (Mary Ann Liebert Inc., 2024)Obesity is a major nutritional problem with an increasing prevalence among children and adolescents. The uridine-diphosphate-glucuronosyl-transferase1A1 (UGT1A1) gene encodes the UDP-glucuronosyl transferase enzyme, ... -
Evaluation of the protective and therapeutic effects of extra virgin olive oil rich in phenol in experimental model of neonatal necrotizing enterocolitis by clinical disease score, ınflammation, apoptosis, and oxidative stress markers
Bölükbaş, Ferhan; Eröz, Recep; Bölükbaş, Ferhan; Özkan, Erkan; Erdal, Hüseyin (Springer Science and Business Media Deutschland GmbH, 2024)Necrotizing Enterocolitis (NEC) is an inflammation-associated ischemic necrosis of the intestine. To investigate the effects of extra virgin olive oil (EVOO) on inflammation, oxidative stress, apoptosis, and histological ... -
Evaluation of the protective effects of morin against acrylamide-induced lung toxicity by biomarkers of oxidative stress, inflammation, apoptosis, and autophagy
Yeşildağ, Kerim; Eröz, Recep; Genç, Aydın; Doğan, Tuba; Satıcı, Emine (John Wiley and Sons Inc, 2022)Acrylamide (ACR) has genotoxic, neurotoxic, and carcinogenic effects. From past to present, various plants or their products have been used for therapeutic purposes such as morin. It was aimed to detect possible protective ... -
Evaluation of Y Chromosome Microdeletion and Chromosome Analysis Results in Infertile Male Patients
Yavaş, Cüneyd; Doğan, Mustafa; Eröz, Recep; Canat, Lütfü (Düzce Üniversitesi, 2023)Genetic testing for male infertility is rarely performed in our country. Male infertility is caused by chromosome number or structural problems, Y chromosome deletions and gene alterations. Infertility is a problem seen ... -
Investigation of the forkhead box protein P2 gene by the next-generation sequence analysis method in children diagnosed with specific learning disorder
Yazıcı, Merve; Yektaş, Çiğdem; Eröz, Recep; Kaplan Karakaya; Elif Sümeyra; Sarıgedik, Enes (Wolters Kluwer, 2023)Objective: It was aimed to investigate the role of the forkhead box protein P2 (FOXP2) gene in the cause of specific learning disorder (SLD) with the next-generation sequencing method. Material and methods: The study ... -
The known about familial mediterranean fever: literature review
Erdal, Hüseyin; Eröz, Recep (Aksaray Üniversitesi, 2022)The most common hereditary autoinflammatory disease is Familial Mediterranean Fever (FMF). Generally, FMF consists of acquiring function mutations of the MEFV gene, which is an auxiliary protein in immune regulation. In ... -
May argyrophilic nucleolar organizer regions be the new marker of a hypoxic response in non ST elevation myocardial infarction
Damar, İbrahim Halil; Eröz, Recep (Konuralp Tıp Dergisi, 2022)Non-ST elevation myocardial infarction (NSTEMI) is a type of acute coronary syndrome and its’ incidence is similarly high to ST-elevation myocardial infarction. Nucleolar organizing regions (NORs) are located of the secondary ... -
May argyrophilic nucleolar organizer regions be used as a biomarker for the detection of the degree of ischemic damage instead of tunel in testicular torsion?
Kabaklıoğlu, Murat; Eröz, Recep; Kaya, Murat (MDPI, 2022)Background and Objectives: It is of great importance to obtain information about the severity of ischemic damage and duration of testicular torsion for an effective treatment strategy. Nucleolar-organizing regions (NORs) ... -
A rare TNNT1 gene variant causing creatine kinase elevation in nemaline myopathy: c.271_273del (p.Lys91del)
Yavaş, Cüneyd; Doğan, Mustafa; Eröz, Recep; Türegün, Kübra (Genetics Society of Korea, 2024)Nemaline Myopathy (NM) is a rare genetic disorder that affects muscle function and is characterized by the presence of nemaline rods in muscle fibers. These rods are abnormal structures that interfere with muscle contraction ... -
Study of ten causal genes in Turkish patients with clinically suspected maturity-onset diabetes of the young (MODY) using a targeted next-generation sequencing panel
Doğan, Mustafa; Eröz, Recep; Bolu, Semih; Yüce, Hüseyin; Gezdirici, Alper; Arslanoğlu, İlknur; Taralı, Kerem (Springer, 2022)Background: Maturity-onset diabetes of the young (MODY), which is the most common cause of monogenic diabetes, has an autosomal dominant pattern of inheritance and exhibits marked clinical and genetic heterogeneity. The ... -
Tekrarlayan gebelik kayıpları nedeniyle çalışılan 306 çiftin kromozom analizi ve trombofili parametrelerinin değerlendirilmesi: tek merkez deneyimi
Doğan, Mustafa; Gezdirici, Alper; Yavaş, Cüneyd; Eröz, Recep (Düzce Üniversitesi, 2022)Bu çalışmanın amacı, hastanemize tekrarlayan gebelik kaybı nedeniyle başvuran çiftlere uygun genetik danışmanlık verebilmek için hem majör kromozom anomalilerinin hem de trombofili parametrelerinin etiyolojideki rolünü ...
