Browsing by Author "Öz, Mehmet"
Now showing items 1-8 of 8
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The antinociceptive effect of Adalimumab, a TNF-Alpha Inhibitor, in a Mice model of inflammatory pain
Öz, Mehmet; Şimşek, Hasan (2022)The aim of this study, evaluate the nociceptive effect of adalimumab, a TNF-alpha inhibitor, on formalin-induced inflammatory pain in mice. The antinociceptive activity of adalimumab was determined on adult male BALB-C ... -
Carvacrol Reduces Mercuric Chloride-Induced Testicular Toxicity by Regulating Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histopathological Changes
Şimşek, Hasan; Gür, Cihan; Küçükler, Sefa; İleritürk, Mustafa; Akaras, Nurhan; Öz, Mehmet; Kandemir, Fatih Mehmet (Springer, 2024)Mercuric chloride (HgCl2) is a heavy metal that is toxic to the human body. Carvacrol (CAR) is a flavonoid found naturally in plants and has many biological and pharmacological activities including anti-inflammatory, ... -
The Effect of High Salt Diet on Anxiety-Depression-Like Behaviors and Cognitive Function in Female and Male Mice
Şimşek, Hasan; Öz, Mehmet (Wiley, 2023)The Effect of High Salt Diet on Anxiety-Depression-Like Behaviors and Cognitive Function in Female and Male Mice... -
Effects of Spirulina on Some Oxidative Stress Parameters and Endurance Capacity in Regular and Strenuous Exercises
Öz, Mehmet; Gökbel, Hakkı (Hashemite University, 2023)We examined the effects of spirulina supplementation on oxidative status in plasma, liver and muscle tissue and endurance capacity in moderate and exhaustive swimming exercise in rats. Method: Animals were divided into six ... -
Interaction of Nitrergic and Cholinergic Systems on Anxiety and Depression-Like Behaviors in Diabetic Rats with Streptozotocin
Öz, Mehmet; Aslanlar, Durmuş Ali; Nurullahoğlu Atalık, Kısmet Esra (Wiley, 2023)Interaction of Nitrergic and Cholinergic Systems on Anxiety and Depression-Like Behaviors in Diabetic Rats with Streptozotocin... -
N-acetylcysteine ameliorates chemotherapy-induced impaired anxiety and depression-like behaviors by regulating inflammation, oxidative and cholinergic status, and BDNF release
Aslanlar, Durmuş Ali; Vişneci, Emin Fatih; Öz, Mehmet; Atalık, K. Esra Nurullahoğlu (Elsevier, 2024)Mood disorders caused by chemotherapy have become more important as the survival of cancer patients increases, and new studies in this field will contribute to the prevention of this disorder. For this purpose, we used ... -
The protective effects of chrysin on cadmium-induced pulmonary toxicity; a multi-biomarker approach
Akaras, Nurhan; İleritürk, Mustafa; Gür, Cihan; Küçükler, Sefa; Öz, Mehmet; Kandemir, Fatih Mehmet (Springer Science and Business Media Deutschland GmbH, 2023)This study aimed to determine the potential protective effects of chrysin (CHR) on experimental cadmium (Cd)-induced lung toxicity in rats. To this end, rats were divided into five groups; Control, CHR, Cd, Cd + CHR25, Cd ... -
A TNF-α inhibitor abolishes sepsis-induced cognitive impairment in mice by modulating acetylcholine and nitric oxide homeostasis, BDNF release, and neuroinflammation
Öz, Mehmet; Erdal, Hüseyin (Elsevier B.V., 2024)Neurodegenerative disorders have a pathophysiology that heavily involves neuroinflammation. In this study, we used lipopolysaccharide (LPS) to create a model of cognitive impairment by inducing systemic and neuroinflammation ...