A combined fracture and mortality risk index useful fortreatment stratification in hip fragility fractures

Basit Öğe Kaydı
dc.authorid0000-0001-6841-7978
dc.authorid0000-0003-1009-5042
dc.authorid0000-0002-9759-3062
dc.authorid0000-0002-8625-8648
dc.authorid0000-0001-8767-892X
dc.authorid0000-0003-0246-4418
dc.authorid0000-0002-9690-8907
dc.authorid0000-0002-0783-5591
dc.authorid0000-0002-5204-1029
dc.contributor.authorSezgin, Erdem Aras
dc.contributor.authorTor, Ahmet Toygun
dc.contributor.authorMarkeviciute, Vetra
dc.contributor.authorSirka, Aurimas
dc.contributor.authorTarasevičius, Šarūnas
dc.contributor.authorRaina, Deepak Bushan
dc.contributor.authorLiu, Yang
dc.contributor.authorIsaksson, Hanna
dc.contributor.authorTägil, Magnus
dc.contributor.authorLidgren, Lars
dc.date.accessioned2025-09-08T12:50:40Z
dc.date.available2025-09-08T12:50:40Z
dc.date.issued2021
dc.departmentTıp Fakültesi
dc.description.abstractIn this study, we aimed to assess the stratification abilityof the Fracture and Mortality Risk Evaluation (FAME) index forreoperation, new fragility fracture, and mortality during one-yearfollow-up. Patients and methods: Between November 2018 and July 2019,a total of 94 consecutive hip fragility fracture patients fromtwo centers (20 males, 74 females; mean age: 79.3±8.9 years;range, 57 to 100 years) were retrospectively analyzed. The patientswere classified into high, intermediate, and low fracture andmortality risk groups according to the Fracture Risk AssessmentTool (FRAX) score and Sernbo score, respectively, as well asnine combined categories according to the FAME index. Hospitalrecords were reviewed to identify re-fractures (reoperations,implant failure, new fragility fractures on any site) and mortality atone year following the FAME index classification. Results: Overall re-fracture and mortality rates were 20.2% and33%, respectively. High fracture risk category (FRAX-H) wassignificantly associated with higher re-fracture (odds ratio [OR]:2.9, 95% confidence interval [CI]: 1-8.2, p=0.037) and mortalityrates compared to others (OR: 3.7, 95% CI: 1.5-9.3, p=0.003).The patients classified within the FRAX-H category (n=35) haddifferent mortality rates according to their Sernbo classification;i.e., patients classified as low mortality risk (Sernbo-L) (n=17) hadlower mortality rates compared to others in this group (n=18) (35.3%and 66.7%, respectively), indicating a low statistical significance(OR: 0.3, 95% CI: 0.1-1.1, p=0.063). Similarly, within patientsclassified in Sernbo-L category (n=64), those classified as highfracture risk (FRAX-H) (n=17) had significantly higher re-fracturerates compared to others in this group (n=47) (35.3% and 8.5%,respectively), (OR: 5.9; 95% CI: 1.4-24.5), (p=0.017). Multivariatelogistic regression analyses adjusting for covariates (age, sex, lengthof hospital stay and BMI) yielded similar results. Conclusion: The FAME index appears to be a useful stratificationtool for allocating patients in a randomized-controlled trial foraugmentation of hip fragility fractures.
dc.identifier.doi10.52312/jdrs.2021.382
dc.identifier.endpage589
dc.identifier.issn2687-4784 / 2687-4792
dc.identifier.issue3
dc.identifier.startpage583
dc.identifier.urihttps://doi.org/10.52312/jdrs.2021.382
dc.identifier.urihttps://hdl.handle.net/20.500.12451/14183
dc.identifier.volume32
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorSezgin, Erdem Aras
dc.institutionauthorid0000-0001-5869-6571
dc.language.isoen
dc.publisherBayçınar Tıbbi Yayıncılık
dc.relation.ispartofJoint Diseases and Related Surgery
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAugmentation
dc.subjectHip Fracture
dc.subjectOsteoporosis
dc.subjectRisk Factors
dc.subjectStratification
dc.titleA combined fracture and mortality risk index useful fortreatment stratification in hip fragility fractures
dc.typeOther

Dosyalar

Orijinal paket
Listeleniyor 1 - 1 / 1
Küçük Resim
İsim:
sezgin-erdem aras-2021.pdf
Boyut:
389.07 KB
Biçim:
Adobe Portable Document Format
İndir
Lisans paketi
Listeleniyor 1 - 1 / 1
[ X ]
İsim:
license.txt
Boyut:
1.17 KB
Biçim:
Item-specific license agreed upon to submission
Açıklama:
İndir

Koleksiyon

Makale Koleksiyonu
TR-Dizin İndeksli Yayınlar Koleksiyonu