Modification of quartz crystal microbalance surfaces via electrospun nanofibers intended for biosensor applications

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dc.authoridMutlu, Mehmet -- 0000-0001-7146-1937
dc.contributor.authorRodoplu, Didem
dc.contributor.authorŞen, Yasin
dc.contributor.authorMutlu, Mehmet
dc.date.accessioned13.07.201910:50:10
dc.date.accessioned2019-07-29T19:29:03Z
dc.date.available13.07.201910:50:10
dc.date.available2019-07-29T19:29:03Z
dc.date.issued2013
dc.departmentGüzelyurt Meslek Yüksekokulu
dc.description.abstractThe major aim of this study is to increase the performance of mass sensitive biosensor surfaces by making modifications on quartz crystal microbalance (QCM) surfaces via electrospinning and plasma polymerization techniques. Polyvinyl alcohol (PVA) nanofibers with a diameter of approximately 150 nm were collected on the QCM surfaces by electrospinning technique. Allylamine monomer was used to create specific groups on these nanofiber coated surfaces by plasma polymerization technique. Modified surfaces were characterized by contact angle measurements, scanning electron microscopy, atomic force microscopy, fourier transform infrared spectroscopy and QCM frequency measurements in order to determine the physical and chemical characteristics of the surfaces after each experimental stage. N-H, C-N, C-H and C=O group bands were determined in the IR spectra of the materials. Decrease in the contact angle values of the modified materials indicated the increase in hydrophilicity. Those results showed that amine containing films on the surfaces were successfully deposited using plasma. The performance of modified QCM surfaces was tested via resonance frequency shifts measurements after bovine serum albumin immobilization. In this group of tests, "dip and dry" method and "flow-cell method" were performed and 548 +/- 4 Hz and 50 +/- 5 Hz frequency shifts were obtained respectively. Results of this study revealed that plasma treated electrospun PVA nanofiber modified surfaces can be used for further biosensor applications.
dc.identifier.doi10.1166/nnl.2013.1558
dc.identifier.endpage451en_US
dc.identifier.issn1941-4900
dc.identifier.issn1941-4919
dc.identifier.issue4en_US
dc.identifier.scopusqualityN/A
dc.identifier.startpage444en_US
dc.identifier.urihttps://doi.org/10.1166/nnl.2013.1558
dc.identifier.urihttps://hdl.handle.net/20.500.12451/6120
dc.identifier.volume5en_US
dc.identifier.wosWOS:000317537500004
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.indekslendigikaynakScopus
dc.language.isoen
dc.publisherAmer Scientific Publishers
dc.relation.ispartofNANOSCIENCE AND NANOTECHNOLOGY LETTERS
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/closedAccess
dc.subjectElectrospun Nanofibers
dc.subjectPlasma Surface Modification
dc.subjectQuartz Crystal Microbalance
dc.subjectBiosensors
dc.titleModification of quartz crystal microbalance surfaces via electrospun nanofibers intended for biosensor applications
dc.typeArticle

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