Clinical success of clarithromycin, amoxicillin-clavulanic acid, enrofloxacin and doxycycline in dogs with infectious tracheobronchitis

dc.authorid0000-0002-8473-0072
dc.authorid0000-0003-2789-035X
dc.authorid0000-0002-4805-0993
dc.contributor.authorHaydardedeoğlu, Ali Evren
dc.contributor.authorÇolakoğlu, Ekrem Çağatay
dc.contributor.authorKaya, Ufuk
dc.date.accessioned2024-03-18T08:37:52Z
dc.date.available2024-03-18T08:37:52Z
dc.date.issued2023
dc.departmentVeteriner Fakültesi
dc.description.abstractCanine infectious tracheobronchitis (ITB) is a highly contagious disease of dogs expressed with remarkable respiratory signs. Therapy with antibiotics in canine ITB still remains questionable. The purpose of this study was to compare the clinical success of clarithromycin, amoxicillin-clavulanic acid, enrofloxacin and doxycycline in the treatment of canine ITB. Client-owned dogs with canine ITB signs (n=60) were enrolled in this prospective, controlled, and randomized blinded clinical trial. A computer-generated list randomization was employed to assign the dogs equally into the Group CLA: clarithromycin (25 mg/kg, PO), the Group AMX: amoxicillin and clavulanic acid (25 mg/kg, PO), the Group ENR: enrofloxacin (2.5 mg/kg, PO), and the Group DOX: doxycycline (5 mg/kg, PO). The administration of CLA alleviated the cough sign earlier than DOX. The recovery time of oculonasal discharge in group CLA were also earlier compared to the other groups. The tracheal sensitivity also disappeared earlier in the Groups CLA and AMX. In conclusion although there is no always statistically significance between groups, clarithromycin appears to be superior to other antibiotics suggesting that it can be the first antibiotic choice to alleviate the ITB signs in dogs.
dc.identifier.doi10.31797/vetbio.1336336
dc.identifier.endpage215en_US
dc.identifier.isbn2548-1150
dc.identifier.issue3en_US
dc.identifier.startpage210en_US
dc.identifier.urihttps:/dx.doi.org 10.31797/vetbio.1336336
dc.identifier.urihttps://hdl.handle.net/20.500.12451/11473
dc.identifier.volume8en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherİlker ÇAMKERTEN
dc.relation.ispartofJournal of Advances in VetBio Science and Techniques
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectAntibiotics
dc.subjectDog
dc.subjectInfection
dc.subjecttracheobronchitis
dc.titleClinical success of clarithromycin, amoxicillin-clavulanic acid, enrofloxacin and doxycycline in dogs with infectious tracheobronchitis
dc.typeArticle

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