Tükürük bezi patolojilerinde ince iğne aspirasyon biyopsinin histopatolojik korelasyonu
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Tarih
2020
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
KBB-Forum
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Tükürük bezi kitlelerinde ameliyat öncesi tedavi planlamasında sık kullanılan bir yöntem olan ince iğne aspirasyon biyopsisi (İİAB) işleminin güvenilirliğini araştırmak ve tanısal değerini değerlendirmektir. Yöntem: 2015-2020 yılları arasında kliniğimizde tükürük bezi kitlesi nedeniyle opere edilmiş olan 88 hastanın dosyası retrospektif olarak incelendi. Vakaların ameliyat öncesi ultrason (USG) eşliğinde yapılmış olan İİAB sonuçları ile ameliyat sonrası histopatolojik sonuçları karşılaştırılarak analiz edildi. Bu analiz sonucunda İİAB işlemin sensitivitesi, spesifitesi, pozitif prediktif değeri, negatif prediktif değeri ve doğruluk oranı saptandı. Bulgular: Hastaların ortalama yaşı 53,8 yıl idi ve 43 kadın ve 45 erkek hastanın tükürük bezi kitlesi nedeniyle opere edildiği saptandı. Kitlelerin 51'i parotis bezinde, 32'si submandibuler bezde ve 5'i ise minör tükürük bezlerinde idi. İİAB sonuçları incelendiğinde malign olarak en sık skuamöz hücreli karsinom görülürken ve benign olarak ise en sık pleomorfik adenom saptandı. Tükürük bezi kitlelerinde İİAB'nin sensitivitesi %80, spesifitesi %93,2, pozitif prediktif değeri %81,8, negatif prediktif değeri %96,3 ve doğruluk oranı %89,8 idi. İİAB sonucu şüpheli olarak bildirilen vakaların %40'ının histopatolojik olarak malignite ile ilişkili olduğu görüldü. Sonuç: Tükürük bezi kitlelerinde İİAB yüksek sensitivite ve spesifiteye sahip, güvenilir bir yöntemdir. İİAB sonucu şüpheli olarak raporlanan kitlelerin malign olma olasılığı yüksek olup bu vakalarda klinisyenlerin tedavi planlamasında daha dikkatli olmalarıgerekmektedir.
Objective: The aim of this study is to investigate the reliability and diagnostic value of fine needle aspiration biopsy (FNAB), which is a common method in preoperative treatment planning in salivary gland masses. Material and Methods: Medical records of 88 patients who were operated for salivary gland masses in our clinic between 2015-2020 were retrospectively examined. The cases were analyzed by comparing the results of the preoperative ultrasound (USG) guided FNAB and the histopathological results after the surgery. As a result of this analysis, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy rate of the FNAB procedure were determined. Results: The mean age of the patients was 53.8 years and 43 female and 45 male patients were operated due to salivary gland masses. 51 of the masses were in the parotid gland, 32 in the submandibular gland and 5 in the minor salivary glands. When the results of FNAB were examined, squamous cell carcinoma was most common as malignant and pleomorphic adenoma was most common as benign. In salivary gland masses, the sensitivity of FNAB was 80%, specificity 93.2%, positive predictive value 81.8%, negative predictive value 96.3% and accuracy rate 89.8%. It was observed that 40% of the cases whose FNAB results were reported as suspicious were histopathologically associated with malignancy. Conclusion: In salivary gland masses, FNAB is a reliable method with high sensitivity and specificity. Masses reported as suspicious as a result of FNAB are highly likely to be malignant, and in these cases, clinicians need to be more careful in treatment planning.
Objective: The aim of this study is to investigate the reliability and diagnostic value of fine needle aspiration biopsy (FNAB), which is a common method in preoperative treatment planning in salivary gland masses. Material and Methods: Medical records of 88 patients who were operated for salivary gland masses in our clinic between 2015-2020 were retrospectively examined. The cases were analyzed by comparing the results of the preoperative ultrasound (USG) guided FNAB and the histopathological results after the surgery. As a result of this analysis, the sensitivity, specificity, positive predictive value, negative predictive value and accuracy rate of the FNAB procedure were determined. Results: The mean age of the patients was 53.8 years and 43 female and 45 male patients were operated due to salivary gland masses. 51 of the masses were in the parotid gland, 32 in the submandibular gland and 5 in the minor salivary glands. When the results of FNAB were examined, squamous cell carcinoma was most common as malignant and pleomorphic adenoma was most common as benign. In salivary gland masses, the sensitivity of FNAB was 80%, specificity 93.2%, positive predictive value 81.8%, negative predictive value 96.3% and accuracy rate 89.8%. It was observed that 40% of the cases whose FNAB results were reported as suspicious were histopathologically associated with malignancy. Conclusion: In salivary gland masses, FNAB is a reliable method with high sensitivity and specificity. Masses reported as suspicious as a result of FNAB are highly likely to be malignant, and in these cases, clinicians need to be more careful in treatment planning.
Açıklama
Anahtar Kelimeler
Tükürük Bezi Kitleleri, İnce İğne Aspirasyon Biyopsisi, Tümör, Sensitivite, Spesifite
Kaynak
KBB-Forum
WoS Q Değeri
Scopus Q Değeri
Cilt
19
Sayı
4
