Comparison of first admission hemogram parameters and chest computed tomography findings of pediatric COVID-19 patients

dc.contributor.authorSarı, Eyüp
dc.contributor.authorYazıcı, Ramiz
dc.contributor.authorBulut, Bensu
dc.contributor.authorÇoban, Gülnur
dc.contributor.authorAtik, Dilek
dc.contributor.authorKılıçaslan, Cengizhan
dc.date.accessioned2022-10-04T05:41:01Z
dc.date.available2022-10-04T05:41:01Z
dc.date.issued2022
dc.departmentTıp Fakültesi
dc.description.abstractAim : We use computed tomography, which is one of the frequently used imaging tests, both as a disease diagnosis method and to follow the clinical course in COVID-19 patients. This also means radiation exposure. Radiation exposure, especially in pediatric patients, can cause life-threatening diseases. Is there a blood parameter that will reduce this undesirable event and allow estimation of computed tomography findings? Are hemogram analysis, one of the most commonly used blood tests, and tomography findings of the disease related? We designed this study based on the questions. Material and Methods: Among the patients under the age of 18 who applied to the emergency department, those with a positive reverse transcription-polymerase chain reaction (RT-PCR) and chest CT and hemogram were included in the study. Chest CT findings were classified according to the CO-RADS classification. We compared the CO-RADS classification with hemogram parameters and the ratios of these parameters. Results: Platelet-to-lymphocyte ratio (PLR) rates were found to be significantly lower as imaging findings became more severe (<0.05). The ratio of MedianPlatelet Volume and Platelet (MPV/Plt) was found to be significantly higher as the imaging findings worsened (p<0.05). When the relationship between laboratory parameters according to imaging groups in our study was evaluated, there was a moderate negative correlation between lymphocyte and platelet levels and imaging findings (p<0.05). A moderate positive correlation with the monocyte level was found (p<0.05). Discussion: For the CO-RADS classification, it can be said that the patient was established to classify possible COVID-19 patients only according to chest CT. There is no study in the literature on the classification of pediatric patients with RT-PCR positive definite COVID-19 according to chest CT scans and the comparison of laboratory findings of patients with this classification. The combination of laboratory parameters and CO-RADS classification will guide clinicians in pediatric COVID-19 patient management.
dc.identifier.doi10.4328/ACAM.21106
dc.identifier.endpage745en_US
dc.identifier.issn2667-663X
dc.identifier.issue7en_US
dc.identifier.startpage741en_US
dc.identifier.urihttps:/dx.doi.org/10.4328/ACAM.21106
dc.identifier.urihttps://hdl.handle.net/20.500.12451/9720
dc.identifier.volume13en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherBayrakol MP
dc.relation.ispartofAnnals of Clinical and Analytical Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectPediatric COVID-19
dc.subjectCO-RADS
dc.subjectEmergency Department
dc.subjectHemogram Parameters
dc.titleComparison of first admission hemogram parameters and chest computed tomography findings of pediatric COVID-19 patients
dc.typeArticle

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