Can pan-immune inflammation value and systemic inflammatory response index be used clinically to predict inflammation in patients with cataract

dc.contributor.authorAkbulut Yağcı, Betül
dc.contributor.authorErdal, Hüseyin
dc.date.accessioned2024-05-03T06:28:01Z
dc.date.available2024-05-03T06:28:01Z
dc.date.issued2023
dc.departmentTıp Fakültesi
dc.description.abstractAim: It is known that inflammatory processes increase the risk of cataract formation. There are no studies examining inflammatory indices in patients with cataract. Therefore, this is the first study that simultaneously investigates the systemic inflammatory response index (SIRI) and pan-immune-inflammation value (PIV) in patients with cataract. Material and Methods: Ninety-five patients and 80 healthy controls who were examined at the Ophthalmology clinics of Aksaray University Education and Research Hospital between January 2022 and January 2023 were included in this retrospective study. The neutrophil-to-lymphocyte ratio (NLR), platelet-tolymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), systemic immune-inflammation index (SII), SIRI and PIV values were calculated as indicators of the inflammatory process. Results: The mean age of the patients was 68.3 +/- 12.1 years and 54.7% of cataract patients were females. In the control group, the mean age was 66.5 +/- 5.4 years, and 32.5% of the participants were females. There was no significant difference between the patient and control groups in terms of laboratory parameters (p>0.05). In addition, inflammatory indices were calculated for the patient and control groups. No statistically significant difference was found between NLR, PLR, LMR, SII, SIRI, and PIV between the groups (p>0.05). Discussion: This study indicates that SIRI and PIV can be used in the evaluation of cataract patients. Therefore, Hemogram parameters and inflammatory indexes created with their combination may contribute to monitoring the progression of cataracts.
dc.identifier.endpage1067en_US
dc.identifier.issn2667-663X
dc.identifier.issue12en_US
dc.identifier.startpage1064en_US
dc.identifier.urihttps://hdl.handle.net/20.500.12451/11757
dc.identifier.volume14en_US
dc.identifier.wosqualityN/A
dc.indekslendigikaynakWeb of Science
dc.language.isoen
dc.publisherBayrakol Medical Publishing
dc.relation.ispartofAnnals of Clinical and Analytical Medicine
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCataracts
dc.subjectInflammation
dc.subjectSystemic Inflammatory Response Index
dc.subjectPan-Immune-Inflammation Value
dc.titleCan pan-immune inflammation value and systemic inflammatory response index be used clinically to predict inflammation in patients with cataract
dc.typeArticle

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