Prevalence of symptomatic acute cerebral infarction among patients with COVID-19 and D-dimer as a predictor of cerebral infarction
| dc.contributor.author | Dönmez, Recep | |
| dc.contributor.author | Güneş, Muzaffer | |
| dc.contributor.author | Şahin, Oruç | |
| dc.date.accessioned | 2024-07-18T11:56:02Z | |
| dc.date.available | 2024-07-18T11:56:02Z | |
| dc.date.issued | 2024 | |
| dc.department | Tıp Fakültesi | |
| dc.description.abstract | : This study sought to investigate the frequency of symptomatic acute cerebral infarction (sACI) among patients with novel coronavirus (COVID-19) disease and the predictive value of laboratory parameters such as D-dimer and neutrophil-to-lymphocyte ratio (NLR) in sACI. Methods: This retrospective case-control study analyzed the data of 2,378 patients with COVID-19 registered in our database between April 1, 2020 and November 30, 2020. Of these patients, a total of 119 subjects were included in the study, including 31 COVID-19 patients with sACI (patient group) and 88 randomly selected COVID-19 patients without sACI (control group). Categorical variables were compared using Chi-square test and predictive value of the variables was analyzed using receiver operating characteristics (ROC) curve analysis. Results: Thirty one (1.30%) of 2,378 COVID-19 patients had sACI. Mann-Whitney U test showed that median D-dimer, neutrophil and NLR values were significantly higher in the sACI group compared to the control group (p = 0.004, p < 0.048 and p = 0.007, respectively). ROC analysis yielded the following areas under the ROC curve: D-dimer = 0.674 (95% CI, 0.569-0.779), NLR = 0.663 (95% CI, 0.559-0.767) and neutrophils = 0.620 (95% CI, 0.509-0.73). Conclusion: The results of the present study showed that elevated D-dimer levels can be used as a predictor of sACI in COVID-19 patients. | |
| dc.identifier.doi | 10.54029/2024MCE | |
| dc.identifier.endpage | 31 | en_US |
| dc.identifier.issn | 1823-6138 | |
| dc.identifier.issue | 1 | en_US |
| dc.identifier.scopusquality | Q4 | |
| dc.identifier.startpage | 27 | en_US |
| dc.identifier.uri | https:/dx.doi.org/10.54029/2024MCE | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/12159 | |
| dc.identifier.volume | 29 | en_US |
| dc.indekslendigikaynak | Scopus | |
| dc.language.iso | en | |
| dc.publisher | ASEAN Neurological Association | |
| dc.relation.ispartof | Neurology Asia | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Acute Cerebral Infarction | |
| dc.subject | COVID-19 Disease | |
| dc.subject | D-dimer | |
| dc.subject | Frequency | |
| dc.subject | Neutrophil/ lymphocyte Ratio | |
| dc.subject | Symptomatic | |
| dc.title | Prevalence of symptomatic acute cerebral infarction among patients with COVID-19 and D-dimer as a predictor of cerebral infarction | |
| dc.type | Article |
