Perkütan koroner girişim ile tedavi edilen safen ven greft hastalarında nötrofil-lenfosit oranı ile majör advers kardiyak olaylar arasındaki ilişki
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Dosyalar
Tarih
2018
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Medikal Yayıncılık
Erişim Hakkı
info:eu-repo/semantics/openAccess
Özet
Amaç: Safen ven greft hastalığında perkütan koroner girişim ile revaskülarizasyon sağlanan hastalarda işlem öncesi nötrofil lenfosit oranı ile uzun dönem kardiyovasküler sonuçlar arasındaki ilişkiyi değerlendirmeyi araştırdık. Gereç ve Yöntem: Safen ven grefte perkütan girişim yapılan hastalar retrospektif olarak taranarak toplamda 98 hasta; majör olumsuz kardiyak olayların varlığına (42 hasta) veya yokluğuna (56 hasta) göre iki gruba ayrıldı. Grupların işlem öncesi nötrofil lenfosit oranları karşılaştırıldı. Bulgular: Majör olumsuz kardiyak olayların olduğu grupta nötrofil lenfosit oranı, total beyaz kan hücre sayısı ve C-reaktif protein seviyesi majör olumsuz kardiyak olayların olmadığı gruba kıyasla anlamlı olarak yüksek bulunmuştur. Sonuç: Safen ven greft hastalığında perkütan koroner girişim öncesi nötrofil lenfosit oranları gelişebilecek kardiyovasküler olayları tahmin etmede kullanılabilen ucuz ve kolay ulaşılabilir bir belirteçtir.
Objectives: In this study, we aimed to investigate relationship between neutrophil/lymphocyte ratio and the long term cardiovascular outcomes in saphenous vein graft disease who were revascularizated with percutaneous coronary intervention. Material and Method: We retrospectively analyzed 98 patients (mean age 64.4±9.3 and 76% men) with significant saphenous vein graft disease whom treated with percutaneous coronary intervention. Of all the participants, 42 patients experienced one or more major adverse cardiac events and 56 of them were free of major adverse cardiac events. Results: The median follow-up period of the study was 47.3 months. Patients with major adverse cardiac events have significantly higher neutrophil to lymphocyte ratio when compared to patients without major adverse cardiac events (3.4±1.4 vs. 2.3±0.8, p <0.001). Higher white blood cell counts, neutrophil counts, CRP levels and lower lymphocyte counts were significantly associated with major adverse cardiac events. Conclusion: Higher neutrophil /lymphocyte ratio values were associated with major adverse cardiac events in patients with saphenous vein graft disease revascularized by percutaneous coronary intervention. It can be used in this era, because it is an inexpensive and readily available marker that provides an additional level of risk scores in predicting in hospital and long-term outcomes in patients with saphenous vein graft disease.
Objectives: In this study, we aimed to investigate relationship between neutrophil/lymphocyte ratio and the long term cardiovascular outcomes in saphenous vein graft disease who were revascularizated with percutaneous coronary intervention. Material and Method: We retrospectively analyzed 98 patients (mean age 64.4±9.3 and 76% men) with significant saphenous vein graft disease whom treated with percutaneous coronary intervention. Of all the participants, 42 patients experienced one or more major adverse cardiac events and 56 of them were free of major adverse cardiac events. Results: The median follow-up period of the study was 47.3 months. Patients with major adverse cardiac events have significantly higher neutrophil to lymphocyte ratio when compared to patients without major adverse cardiac events (3.4±1.4 vs. 2.3±0.8, p <0.001). Higher white blood cell counts, neutrophil counts, CRP levels and lower lymphocyte counts were significantly associated with major adverse cardiac events. Conclusion: Higher neutrophil /lymphocyte ratio values were associated with major adverse cardiac events in patients with saphenous vein graft disease revascularized by percutaneous coronary intervention. It can be used in this era, because it is an inexpensive and readily available marker that provides an additional level of risk scores in predicting in hospital and long-term outcomes in patients with saphenous vein graft disease.
Açıklama
Anahtar Kelimeler
Nötrofil-Lenfosit Oranı, Safen Ven Greft Hastalığı, Ateroskleroz, Neutrophil to Lymphocyte Ratio, Saphenous Vein Graft Disease, Atherosclerosis
Kaynak
MN Kardiyoloji
WoS Q Değeri
Scopus Q Değeri
Cilt
25
Sayı
2
