Effects of calcium silicate cements on neuronal conductivity
| dc.authorid | 0000-0002-3630-7982 | |
| dc.authorid | 0000-0002-0797-8322 | |
| dc.authorid | 0000-0002-2755-1756 | |
| dc.authorid | 0000-0001-9494-267X | |
| dc.authorid | 0000-0002-9418-2057 | |
| dc.contributor.author | Sungur, Derya Deniz | |
| dc.contributor.author | Onur, Mehmet Ali | |
| dc.contributor.author | Akbay, Esin | |
| dc.contributor.author | Tan, Gamze | |
| dc.contributor.author | Dağlı Cömert, Fügen | |
| dc.contributor.author | Sayın, Taner Cem | |
| dc.date.accessioned | 2022-06-28T07:11:14Z | |
| dc.date.available | 2022-06-28T07:11:14Z | |
| dc.date.issued | 2022 | |
| dc.department | Sabire Yazıcı Fen Edebiyat Fakültesi | |
| dc.description.abstract | Objectives: This study evaluated alterations in neuronal conductivity related to calcium silicate cements (CSCs) by investigating compound action potentials (cAPs) in rat sciatic nerves. Materials and methods: Sciatic nerves were placed in a Tyrode bath and cAPs were recorded before, during, and after the application of test materials for 60-minute control, application, and recovery measurements, respectively. Freshly prepared ProRoot MTA, MTA Angelus, Biodentine, Endosequence RRM-Putty, BioAggregate, and RetroMTA were directly applied onto the nerves. Biopac LabPro version 3.7 was used to record and analyze cAPs. The data were statistically analyzed. Results: None of the CSCs totally blocked cAPs. RetroMTA, Biodentine, and MTA Angelus caused no significant alteration in cAPs (p > 0.05). Significantly lower cAPs were observed in recovery measurements for BioAggregate than in the control condition (p < 0.05). ProRoot MTA significantly but transiently reduced cAPs in the application period compared to the control period (p < 0.05). Endosequence RRM-Putty significantly reduced cAPs. Conclusions: Various CSCs may alter cAPs to some extent, but none of the CSCs irreversibly blocked them. The usage of fast-setting CSCs during apexification or regeneration of immature teeth seems safer than slow-setting CSCs due to their more favorable neuronal effects. | |
| dc.identifier.doi | 10.5395/rde.2022.47.e18 | |
| dc.identifier.endpage | - | en_US |
| dc.identifier.issue | 2 | en_US |
| dc.identifier.startpage | - | en_US |
| dc.identifier.uri | https:/dx.doi.org/10.5395/rde.2022.47.e18. | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/9496 | |
| dc.identifier.volume | 47 | en_US |
| dc.indekslendigikaynak | PubMed | |
| dc.language.iso | en | |
| dc.publisher | PMC | |
| dc.relation.ispartof | Restor Dent Endod | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/openAccess | |
| dc.subject | Apical Extrusion | |
| dc.subject | Bioceramics | |
| dc.subject | Calcium Silicate Cements | |
| dc.subject | Neuronal Conductivity | |
| dc.subject | Neurotoxicity | |
| dc.title | Effects of calcium silicate cements on neuronal conductivity | |
| dc.type | Article |
