Serum IgG threshold values associated with increased risk of diseases in preweaned lambs

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dc.authorid0000-0003-2674-1010
dc.authorid0000-0003-1183-6076
dc.authorid0000-0001-7958-7251
dc.authorid0000-0002-6660-2149
dc.contributor.authorGokçe, Erhan
dc.contributor.authorAtakişi, Onur
dc.contributor.authorCihan, Pınar
dc.contributor.authorKırmızıgül, Ali Haydar
dc.contributor.authorErdoğan, Hidayet Metin
dc.date.accessioned2025-09-15T06:12:39Z
dc.date.available2025-09-15T06:12:39Z
dc.date.issued2025
dc.departmentVeteriner Fakültesi
dc.description.abstractSerum IgG cut-off points associated with increased risk of septicemia, fatigue anorexi syndrome (FAS), diar- rhea and pneumonia in preweaned lambs was investigated in this study. The study involved 347 Akkaraman crossbred lambs born on two farms in Kars, Turkey. Blood samples were collected 24±1 h after birth and serum IgG concentrati- on was measured by ELISA assay and cut-off values for each disease were determined. Neonatal lambs with diarrhea, FAS and septicaemia had statistically significantly lower IgG concentrations compared to healthy lambs (P<0.05). Cri- tical SIgGC-24 cut-off values for increased risk of diarrhea, FAS and septicaemia in neonatal lambs were <800, <1000 and <200 mg/dl. In post-neonatal period, SIgGC-24 (mg/dL) was lower in only lambs with pneumonia compared to he- althy lambs (P<0.05). The risk of developing septicaemia (IgG<200 mg/dL vs IgG>200 mg/dL), diarrhoe (IgG<800 mg/ dL vs IgG>800 mg/dL), FAS (IgG<1000 mg/dL vs IgG>1000 mg/dL) and pneumonia ((IgG<1000 mg/dL vs IgG>1000 mg/dL) was 203, 6, 18 and 12 times higher, respectively. A threshold vaule of IgG<998 mg/dL and IgG<193 mg/ dL were determined for neonatal morbidity and mortality, respectively. An appropriate colostrum management may help to maintain the health of pre-weaning lambs, thereby improving the productivity and profitability of sheep farms..
dc.identifier.endpage25
dc.identifier.issn2548-1150
dc.identifier.issue1
dc.identifier.startpage17
dc.identifier.urihttps://hdl.handle.net/20.500.12451/14380
dc.identifier.volume10
dc.indekslendigikaynakTR-Dizin
dc.institutionauthorErdoğan, Hidayet Metin
dc.institutionauthorid0000-0003-1261-4352
dc.language.isoen
dc.publisherİlker ÇAMKERTEN
dc.relation.ispartofJournal of Advances in VetBio Science and Techniques
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectColostrum
dc.subjectIgG cut-offs
dc.subjectLamb Health
dc.subjectPassive Immunity
dc.titleSerum IgG threshold values associated with increased risk of diseases in preweaned lambs
dc.typeArticle

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