The effects of propofol on Doppler echocardiographic values of the aorta, main pulmonary artery, and mitral E wave in New Zealand white rabbits
| dc.contributor.author | Çetinkaya, Mehmet Alper | |
| dc.contributor.author | Kaya, Mahir | |
| dc.date.accessioned | 2025-10-15T07:41:59Z | |
| dc.date.available | 2025-10-15T07:41:59Z | |
| dc.date.issued | 2024 | |
| dc.department | Veteriner Fakültesi | |
| dc.description.abstract | The aim of this study was to determine the effects of propofol on acceleration time (AT), ejection time (ET), AT / ET ratio obtained from the aorta (Ao) and main pulmonary artery (MPA) and Doppler echocardiographic values of mitral E wave (E) in New Zealand white rabbits. Echocardiographic evaluation was performed in 40 conscious rabbits and repeated after propofol administration. The baseline mean values were 0.028±0.006 second (s) for Ao-AT, 0.116±0.017 s for Ao-ET, 0.24±0.036 for Ao-AT / ET, 0.05±0.01 s for MPA-AT, 0.137±0.018 s for MPA-ET, 0.38±0.037 s for MPA-AT/ET, 84.13±18.26 cm/s for E peak velocity, 3.06±1.38 mmHg for E peak pressure, 0.069±0.018 s for E duration, 0.046±0.015 s for E deceleration time (Edec)._After propofol administration, the decrease in velocity (P = 0.044, 90.76±14.39 vs. 83.04±12.24) and peak pressure gradient (P = 0.036, 3.47±1.01 vs. 2.98±0.77) of Ao wave, as well as left ventricular ejection fraction (EF) and fractional shortening (FS) was statistically significant (P < 0.001, 70.1±4.47 vs. 63.2±3.79, 37.85±3.74 vs. 32.15±2.43, respectively); AT was longer (P < 0.05) and AT/ET was increased (P < 0.001) in both Ao and MPA. Among Doppler echocardiographic parameters of the E wave, there was only a statistically significant difference for Edec (P = 0.008). In the presented study, while the effect of propofol is minimal on Edec, its effects on aortic and pulmonic AT/ET values, as well as EF and FS values, should be taken into consideration. | |
| dc.identifier.doi | 10.56808/2985-1130.3710 | |
| dc.identifier.issn | 01256491 | |
| dc.identifier.issue | 4 | |
| dc.identifier.scopus | 2-s2.0-85219685848 | |
| dc.identifier.scopusquality | Q4 | |
| dc.identifier.uri | https://doi.org/10.56808/2985-1130.3710 | |
| dc.identifier.uri | https://hdl.handle.net/20.500.12451/14798 | |
| dc.identifier.volume | 54 | |
| dc.indekslendigikaynak | Scopus | |
| dc.institutionauthor | Kaya, Mahir | |
| dc.language.iso | en | |
| dc.publisher | Chulalongkorn University Printing House | |
| dc.relation.ispartof | Thai Journal of Veterinary Medicine | |
| dc.relation.publicationcategory | Makale - Uluslararası Hakemli Dergi - Kurum Öğretim Elemanı | |
| dc.rights | info:eu-repo/semantics/closedAccess | |
| dc.subject | Acceleration and Ejection Time | |
| dc.subject | Aorta | |
| dc.subject | Echocardiography | |
| dc.subject | Main Pulmonary Artery | |
| dc.subject | Propofol | |
| dc.subject | Rabbit | |
| dc.title | The effects of propofol on Doppler echocardiographic values of the aorta, main pulmonary artery, and mitral E wave in New Zealand white rabbits | |
| dc.type | Article |
