Does the use of cannabinoids affect the ocular surface

dc.authorid0000-0001-7447-2551
dc.authorid0000-0003-0339-4140
dc.authorid0000-0002-0034-5186
dc.authorid0000-0001-9289-837X
dc.contributor.authorMutlu, Kayhan
dc.contributor.authorCumurcu, Tongabay
dc.contributor.authorElbozan Cumurcu, Birgül
dc.contributor.authorŞamdancı, Emine
dc.date.accessioned2022-07-29T05:42:55Z
dc.date.available2022-07-29T05:42:55Z
dc.date.issued2022
dc.departmentTıp Fakültesi
dc.description.abstractTo examine tear functions and ocular surface variables in patients with cannabis addiction. Materials and Methods: This clinical trial was planned as a prospective case-control study. In this study, 51 male patients with cannabis addiction (group 1) and 51 healthy volunteers (group 2) with similar demographic characteristics were included. Visual acuity, spherical equivalent, biomicroscopic examination, Schirmer test, tear break-up time (TBUT), and impression cytology (Nelson scores) results were recorded, and the 2 groups were compared with each other. Results: The mean Schirmer values were 9.68 ± 6.8 mm and 8.39 ± 4.08 mm in group 1 and group 2 (p = 0.97), respectively, whereas the mean TBUT values were 9.96±3.9 and 9.29±4.01s. (p = 0.35) and the mean Nelson scores were 1.49±1 and 1.25±0.97 in group 1 and group 2, respectively (p = 0.26). Conclusion: In this study, the effects of cannabis addiction on the ocular surface were evaluated using Schirmer, TBUT, and impression cytology methods. In the statistical analysis, no significant difference was found compared to the control group. This study showed that tear production, tear film stability, and impression cytology of patients with cannabis addiction were not different from the control group.
dc.identifier.doi10.5455/annalsmedres.2021.07.484
dc.identifier.endpage421en_US
dc.identifier.issn2636-7688
dc.identifier.issn2636-7688
dc.identifier.issue5en_US
dc.identifier.startpage418en_US
dc.identifier.urihttps://dx.doi.org/10.5455/annalsmedres.2021.07.484
dc.identifier.urihttps://hdl.handle.net/20.500.12451/9617
dc.identifier.volume29en_US
dc.indekslendigikaynakTR-Dizin
dc.language.isoen
dc.publisherİnönü Üniversitesi
dc.relation.ispartofAnnals of Medical Research (Ann Med Res)
dc.relation.publicationcategoryMakale - Ulusal Hakemli Dergi - Kurum Öğretim Elemanı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectCannabis Addiction
dc.subjectOcular Surface
dc.subjectImpression Cytology
dc.subjectTear Functions
dc.titleDoes the use of cannabinoids affect the ocular surface
dc.typeArticle

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