Aksaray Üniversitesi Kurumsal Akademik Arşivi
DSpace@Aksaray, Aksaray Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Demographic, clinical, and Angiographic characteristics of atrial fibrillation patients suffering from de Novo acute myocardial infarction: A subgroup analysis of the MINOCA-TR study population
(CardioFront LLC, 2021) Coner, Ali; Ekmekçi, Cenk; Aydın, Gökhan; Kılavuz Doğan, Yasemin; Arıcan Özlük, Özlem; Kılıç, Salih; Çelik, Yunus; İnci, Sinan
Background: Atrial fibrillation (AF) prevalence in patients with acute myocardial infarction (MI) ranges from 3% to 25%. However demographic, clinical, and angiographic characteristics of AF patients who admitted with de novo MI are unclear. The aim of this study was to investigate the prevalence of patients presenting with de novo MI with AF. Methods: The study was performed as a sub-study of the MINOCA-TR (Myocardial Infarction with Non-obstructive Coronary Arteries in Turkish Population) Registry, a multicenter, cross-sectional, observational, all-comer registry. MI patients without a known history of stable coronary artery disease and/or prior coronary revascularization were enrolled in the study. Patients were divided into AF and Non-AF groups according to presenting cardiac rhythm. Results: A total of 1793 patients were screened and 1626 were included in the study. The mean age was 61.5 (12.5) years. 70.7% of patients were men. The prevalence of AF was 3.1% (51 patients). AF patients were older [73.4 (9.4) vs. 61.0 (12.4) years, p<0.001] than non- AF patients. The proportion of women to men in the AF group was also higher than in the non-AF group (43.1% vs. 28.7%, p=0.027). Only 1 out of every 5 AF patients (10 patients, 19.6%) was using oral anticoagulants (OAC). Conclusions: AF prevalence in patients presenting with de novo MI was lower than previous studies that issued on AF prevalence in MI cohorts. The majority of AF patients did not have any knowledge of their arrhythmia and were not undergoing OAC therapy at admission, emphasizing the vital role of successful diagnostic strategies, patient education, and implementations for guideline adaptation.
Vitamin D intoxication due to misuse: 5-year experience
(Elsevier Masson s.r.l., 2021) Çağlar, A.; Tuğçe Çağlar, H.
Introduction: Vitamin D intoxication (VDI) is a well-known cause of hypercalcemia in children and leads to serious kidney, heart, and neurological problems. In the treatment of VDI, the goal is to correct hypercalcemia. Our aim was to evaluate the clinical features of patients with VDI, identify the causes of VDI in our region, and help guide precautions and treatment of VDI. Materials and methods: The medical records of patients with VDI presenting between January 2015 and December 2019 were retrospectively analyzed. Results: In total, 38 patients aged 0.3–4 years including 20 males (52.6%) were included in the study. Vomiting (65.8%), loss of appetite (47.4%), and constipation (31.6%) were the most common symptoms. The cause of intoxication was prescribed D3 vials in 23 patients, non-prescribed D3 vials in nine patients, and incorrectly produced fish oil supplement in six patients. Admission serum calcium and 25 (OH) D levels were 3.75 ± 0.5 mmol/L and 396 ± 110 ng/mL, respectively. A statistically significant correlation was found between the serum calcium levels at the time of diagnosis and the dose of vitamin D received, serum 25 (OH) D, phosphorus, and parathyroid (PTH) levels. Nephrocalcinosis was present in 15 (39.5%) patients. The mean time to achieve normocalcemia was 6.18 ± 2 days. The mean time to achieve normocalcemia in patients treated with pamidronate was 5.94 ± 0.7 days. Conclusion: Stoss therapy should not be administered for children of families with problems of adherence to treatment. It should be noted that VDI may develop as a result of improperly produced nutritional supplements. General practitioners and pediatricians must be aware of VDI risks and explain them to parents. Pamidronate is effective for treating VDI in children.
Risk of hypercalcemia in elderly patients with hypervitaminosis D and intoxication
(Acta Endocrinologica Foundation, 2021) Batman, Adnan; Altuntaş, Y.
Objective. We aimed to determine the risk of hypercalcemia in a geriatric population with very high dose levels of 25-hydroxy-vitamin D (25(OH)D). Patients and Method. This study was designed as a retrospective, cross-sectional two-center study for examining the elderly patients with very high 25(OH)D levels (>88ng/mL) between January 2014 and December 2019. After recruitment, subgroup analyses of the patients were performed based on their calcium and vitamin D levels. Results. A total of 81.101 elderly patients, who had been evaluated for their vitamin D levels, were screened. Of the 458 (0.6%) elderly patients with 25(OH)D>88 ng/ mL according to our criteria, 217 patients with complete data were accepted into our study. The median 25(OH)D level was 103.7ng/mL (min-max:88.2-275.9). Most of the elderly patients (86.6%) with very high 25(OH)D levels were normocalcemic. When patients with hypercalcemia were compared with normocalcemic group, no difference was observed in the levels of 25(OH)D, intact parathormone (iPTH), phosphorus, alkaline phosphatase (ALP), and their age. However, the PTH suppression rate was significantly higher in hypercalcemic group (p=0.005). Conclusion. The elderly patients with very high 25(OH)D levels would appear to be mostly normocalcemic whereas life-threatening hypercalcemia would also occur. Treatment and follow-up planning should be done according to the clinical guideline recommendations.
The others of Babel in the context of orientalism
(IGI Global, 2021) Sarı, Gülşah; Gültekin, Gökhan
Cinema is a branch of art that uses images. In this context, cinema can take Orientalism to a different dimension with images by using its own narrative language. In this study, the 2006 film Babel by Mexican director Alejandro G. Iñárritu is analyzed in order to show how the orientalist elements were constructed in the West's (Occident) otherization of the East (Orient). As a result of the analysis, it is seen that Babel put forward everything that is related to the East since its first scene, mostly with an orientalist point of view, in a way that alienates the East. The film is based on the fact that the language of the marginalized can never be understood, and therefore, there is always a difference between the West and the East.
Halophytes as medicinal herbs
(Springer International Publishing, 2021) Demir, Aynur; Tıpırdamaz, Rukiye
Halophytes are durable to stress conditions and can adapt to saline areas, thanks to their genetic structure, morphological, and anatomic differentiation. As significant ecologically as well as economically, these plants are used extensively in medicine. Primary and secondary metabolites in their various sections such as roots, stems, leaves, flowers, and seeds are applied directly or indirectly in treatments for various illnesses related to digestion and respiration systems, skin, rheumatism, and urinary system. This study evaluates and classifies halophytes in terms of the areas in traditional medicine where they are used, their sections being used, and the methods which they are used. Additionally, Halophytes are analyzed with regard to their potential uses in modern medicine as antioxidant, antitumor, anticancer, and antibacterial drugs.
