Aksaray Üniversitesi Kurumsal Akademik Arşivi
DSpace@Aksaray, Aksaray Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Use of metallic nanoparticles in plants: recent advances and future challenges
(Elsevier, 2024) Tan, Gamze; Turhan, Ece
The increase in food demand due to population growth necessitates the more efficient use of water and soil resources; however, unconscious use of chemical inputs, excessive irrigation, and environmental pollution has adversely affected growing conditions, health, and eventually crop yield. Unlike conventional delivery, thanks to the controlled release mechanism, nanobased systems hold promise for enhancing the therapeutic efficacy of drugs and alleviating their side effect profiles. Nanotechnology has not only come to the fore in the field of biomedicine but also in agriculture, especially in the prevention, diagnosis, monitoring, and treatment of plant diseases, reducing stress levels in plants, reducing the use of chemicals, managing water and nutrients, struggling with pests and insects, and so on. However, nanomaterials to be used in therapeutic systems are expected to be stable, causing relatively low toxic effects, easy to synthesize, cost-effective, biocompatible, and tunable functionality with therapeutic molecules. Metallic nanoparticles stand out in targeting and controlled release applications due to their colloidal stability and tunable characteristics of size, shape, and surface functionality. This section introduces classifications of nanomaterials, metallic nanoparticles and their synthesis routes, and characterization techniques. In addition, it puts a particular emphasis on the contributions of metallic nanoparticles to plant growth and development, crop yield, the diagnosis, treatment, and monitoring of herbal diseases, as well as their protective roles under harsh conditions, and future demands and challenges.
Relationship between coronavirus anxiety, resilience, and attitudes toward complementary and alternative treatment among patients admitted to the COVID-19 Outpatient Clinic
(National Scientific Medical Center, 2024) Karakoyun, Ahmet; Bahadır YIlmaz, Emel; Yüksel, Arzu
Aim: During the COVID-19 pandemic, the studies showed an increase in complementary and alternative therapy use. This study aimed to determine the relationship between coronavirus anxiety, resilience, and attitudes toward complementary and alternative treatment among patients admitted to the COVID-19 outpatient clinic. Material and methods: This is a descriptive and relational study. The sample consisted of 364 patients who applied to the pandemic outpatient clinic of a training and research hospital in Turkey. Data were collected using the Coronavirus Anxiety Scale, Brief Resilience Scale, and Scale for Attitudes toward Complementary and Alternative Medicine. The Mann–Whitney U test, the Kruskal–Wallis test, and the Spearman correlation test were used in data analysis. Results: There was a moderate and negative correlation (r = −0.332) between attitudes toward complementary and alternative medicine and coronavirus anxiety, and a moderate and positive correlation (r = 0.348) between attitudes toward complementary and alternative medicine and resilience (p < 0.01). Additionally, there was a moderate and negative correlation between coronavirus anxiety and resilience (r = −0.667; p < 0.01). Conclusion: In the COVID-19 pandemic process, it is essential to follow up on patients' complementary and alternative medicine use, inform them, and determine their causes.
Rethinking the risk: evalution of the malignant potential of Non-16 and 18 HPV Types VIA colposcopic results
(Yuzuncu Yil Universitesi Tip Fakultesi, 2024) Genç, Şerife Özlem; Kurt, Begüm; Koç, Tülay; Erdal, Hüseyin
The malignancy risks of high-risk HPV types like 16 and 18 are well-known. The oncogenic potential of other HPV types, however, remains unclear. This study reevaluates malignancy risks across HPV types, stressing comprehensive colposcopic evalu ations in cervical cancer screening. Materials and Methods: Conducted at a tertiary care center (January 2021-July 2023), this retrospective study included 138 women divided into two groups: those infected with HPV 16/18 and those with other HPV types. We analyzed and compared colposcopic a nd histopathological outcomes, correlating colposcopic results with biopsy outcomes to assess cervical neoplasia. Statistical analysis was performed using GraphPad Prism 10 (GraphPad Software Inc.; San Diego, CA, USA). Descriptive statisti cs, including means and standard deviations for continuous variables and frequencies and percentages for categorical variables, were calculated. The chi-square test was used to compare categorical variables between the two groups, and an independent t-test was employed to compare continuous variables. A p-value of less than 0.05 was considered statistically significant. Results: Significant differences were noted between groups. While HPV 16 and 18 are linked to higher cervical neoplasia incidences, non-16/18 HPV types were also frequently associated with smear abnormalities. The average age of first sexual intercourse was 20.49 ± 4.2 years. Forty-nine percent of the women were smokers, 8% had only primary school education, and 78% were homemakers. High rates of known risk factors like low educational and socioeconomic status, and smoking were also significant. Conclusion: Our findings suggest that non-16/18 HPV types might have a higher malignancy potential than HPV 16-18, highlighting their importance in cervical cancer screenings and colposcopic evaluations. The study's small sample size limits its conclusions, pointing to the need for larger studies to refine cervical cancer screening strategies globally.
Isotopic dependence of (n,α) reaction cross sections for Fe and Sn nuclei
(Elsevier B.V., 2024) Küçüksucu, S.; Yiğit, Mustafa
The (n,α) reactions play an important role for the energy generation and the synthesis of chemical elements in the stars, as well as for nuclear engineering and medical applications. The aim of this study is to explore the evolution of (n,α) reactions in Fe and Sn isotope chains in order to assess the cross section properties with the increase of neutron number in target nucleus, and to make a comparison with other relevant neutron induced reactions. The cross section calculations are based on the statistical Hauser-Feshbach and exciton models in TALYS nuclear reaction code, using global optical model potential that is additionally adjusted by the (n,α) cross section data for 54Fe and 118Sn. The calculations of (n,α) reactions in Fe and Sn isotopes provide the insight into their isotopic dependence and properties over the complete relevant range of neutron energies. The cross sections result in pronounced maxima at lower-mass isotopes, and rather strong decrease for neutron-rich nuclei consistent with the reduction of the reaction Q-value and increased contributions from other exit channels from compound nucleus. The analysis of the Maxwellian averaged cross sections at temperatures in stellar environment shows that the (n,α) reactions have significant contributions for low-mass Fe isotopes, that is opposite than for Sn isotopes. For both neutron rich isotopes γ and neutron emissions dominate, with their interplay depending on the temperature involved.
Involvement of microbial species for plant growth promotion and disease suppression
(Elsevier, 2024) Şam, Mesut; Sağlam, Semran; Altındağ, Serap; Sağlam, Necdet
Our need for agricultural production is progressively increasing as a result of the growing global population. It has become more important than ever to eliminate the conditions that affect plant ecosystem adversely, such as pathogenic microorganisms and insects that affect plant health. This has led to a steady rise in our reliance on agrochemicals, which are used to eliminate these unfavorable conditions and are now the most crucial tool for plant protection. These agrochemicals, which can adversely affect both agricultural products and the ecosystem, are not the eventual solution to our problems, and may lose their effectiveness over time since the target organisms develop resistance. Furthermore, the toxic effects of chemical residues in food have significantly changed the communities' consensus on chemicals, leading to studies for alternative solutions.
