Aksaray Üniversitesi Kurumsal Akademik Arşivi
DSpace@Aksaray, Aksaray Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Wastewater treatment: synthesis of effective photocatalysts through novel approaches
(Wiley, 2020) Qureshi, Tahira; Bakhshpour, Monireh; Çetin, Kemal; Topçu, Aykut Arif; Denizli, Adil
Treatment of wastewater and reusability of water systems are crucial aspects. Scientists are focusing on performing water treatment with environmentally friendly and cost-effective methodologies. Previously, sewage has been treated with various physical, chemical, and biological processes. Environmental scientists in this field have been applied to a new class of process called advanced oxidation processes predominantly by using heterogenous photo catalysis, which converts photon energy into chemical energy, for wastewater remediation (industrial, agricultural, and domestic runoff). The process of photocatalysis is getting attention as an effective wastewater treatment methodology due to its efficient degradation of diverse pollutants. Certainly, photocatalysis is an eco-friendly and competent process for wastewater remediation to resolve water pollution problems. In this chapter, we discuss novel approaches for preparing various forms of photocatalyst materials. Besides, the insight of the photocatalytic material properties and modifications on synthesis have been explained.
Theoretical approach to the problem of macro-micro relationships in secondary chemistry teaching: a proposal based on observation and inference
(CEUR-WS, 2020) Sarıtaş, Davut; Özcan, Hasan; Adúriz-Bravo, Agustín
The aim of the present study, of elucidative and argumentative nature, is to propose a first draft for a theoretical approach towards establishing well-founded explanatory relationships between the micro and macro levels of chemical knowledge. The establishment of such an aim is done taking into account that “levels” in chemistry are usually regarded as the cause of many misconceptions among secondary students. We first examine the recent literature of chemistry education addressing the “macro-micro problem”. We then redefine that problem, using the aid of the philosophy of science and the specific philosophy of chemistry, in terms of observations and inferences. We draw attention to the theoretical-empirical, explanatory-descriptive, abstract-concrete, general-factual nature of chemical concepts in science education. Finally, we derive some instructional guidelines that intend to be coherent with currently established knowledge in chemistry education research. We indicate some clues for the design of instructional sequences, laboratory practices, and technology-mediated teaching activities that follow the spirit of our theoretical approach.
(1 → 3)-β-d-glucan enhances the toxicity induced by Bortezomib in rat testis
(Blackwell Publishing Ltd, 2020) Akaras, Nurhan; Abuc, Özlem Özgül; Koç, Kübra; Bal, Tuğba; Geyikoğlu, Fatime; Atilay, Hilal; Erol, Hüseyin Serkan; Yiğit, Serdar; Gül, Murat
We aimed to determine the possible effects of the antioxidant agent (1 → 3)-β-D-glucan on bortezomib-induced rat testis damage. We used five groups of rats; control, (1 → 3)-β-D-glucan (75 mg/kg), bortezomib group, bortezomib + (1 → 3)-β-D-glucan groups (injection of (1 → 3)-β-D-glucan after bortezomib and sacrificed at 48th or 72nd h). The effects of these substances were assessed by measuring the levels of the antioxidant enzymes and LPO, and by performing immunohistochemical analysis with NF-κB. The histology of testis was evaluated using aniline blue staining. (1 → 3)-β-D-glucan leads to significant reductions in the levels of antioxidant enzymes and increased levels of LPO in testes. Moreover, it increased the NF-κB immunopositivity significantly in testis, especially in Bortezomib + (1 → 3)-β-D-glucan group at 48th h. The histological changes were observed in the bortezomib and/or (1 → 3)-β-D-glucan groups. Our results demonstrated that testis damage caused by the treatment with bortezomib was not eliminated by (1 → 3)-β-D-glucan and shockingly it increased the damage. Practical applications: The testis damage caused by the treatment with bortezomib was not eliminated by (1 → 3)-β-D-glucan and as a result, β-1,3-(D)-glucan enhanced the toxicity by leading a decrease in the levels of GSH, SOD, and CAT, thus caused an elevation in the immunoreactivity of NF-κB and altered the histopathological changes by enhancing the toxic effects of bortezomib. The findings of the previous studies about the antioxidative activity of (1 → 3)-β-D-glucan are controversial. So, it is necessary to consider the cytotoxicity of (1 → 3)-β-D-glucan in testis tissue. Thus, more studies on testis tissue are necessary to confirm that (1 → 3)-β-D-glucan is safe as an antioxidant.
Biomedical applications of layer-by-layer self assembly
(Nova Science Publishers, Inc., 2020) Bozdoğan, Betül; Daban, Gizem; Denkbaş, Emir Baki
Layer-by-layer (LbL) self-assembly is the most widely used strategy for the production of functional surfaces with tailored structures and properties such as chemical, biological, optical and electrical. This strategy involves alternately coating the planar or colloidal surfaces with complementary compounds such as oppositely charged polyelectrolytes, inorganic molecules, metal oxides, silica colloids, dyes, clays, nanostructures or biologically active species like enzymes, DNA, viruses, or proteins. The assembly process is driven by noncovalent interactions under mild conditions. LbL is independent of the substrate shape, size or type; environmentally-friendly; high loading capacity of different types of biomolecules into films; allows room temperature processing and low-cost manufacturing. These outstanding advantages of LbL self-assembly make it especially attractive in the biomedical applications. LbL approaches open new horizon for design biocompatible, antimicrobial, hydrophobic, hydrophilic, electrically conductive, chemically stable, hydrolyzable, adhesive, non-adhesive, anti-thrombotic, semipermeable, stimuli-sensitive surfaces and for loading bioactive molecules to design tissue scaffolds, cardiovascular devices, implants, wound healing dressing, bone grafts, biosensors, drug delivery, and release systems.
The concept of involvement and the high involvement model
(Peter Lang AG, 2020) Baritci, Zühal Fidan
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