Aksaray Üniversitesi Kurumsal Akademik Arşivi
DSpace@Aksaray, Aksaray Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Acute toxicity and therapeutic application of Zizyphus lotus and Ruta chalepensis phenolic extracts in treatment of gastroenteritis induced by Salmonella enterica subsp. arizonae
(University of Szeged, 2022) Bekkar, Nour El Houda; Bouabsa, Foufa; Meddah, Boumediene; Keskin, Bahadır; Çakmak, Yavuz Selim; Tou, Abdenacer
This study aimed to evaluate the antigastroenteritis effect against Salmonella enterica subsp. arizonae after therapeutic application of hydromethanolic extracts (MeOH.E) and aqueous extracts (Aq.E) of Zizyphus lotus (ZL) and Ruta chalepensis (RC). Acute oral toxicity was elucidated using in vivo methods and antigastroenteritis effect were evaluated using S. enterica subsp. arizonae-induced diarrheal model. Furthermore, test groups were treated with 400 mg/kg of the MeOH.E and Aq.E of each plant, while the control group was given neomycin (200 mg/kg) as standard antibiotic treatment, positive and negative controls were given the infectious germ (4 × 106 cells/mL) and 0.9% saline solution NaCl (10 ml/kg), respectively. Both plants extracts showed no toxicity for all the animals, so the LD50 was found to be greater than 5000 mg/kg. Moreover, an important bactericidal effect, using both plants extracts was determined against S. enterica subsp. arizonae cells in the intestine. In parallel, a decrease in alkaline phosphatase, amino alanine transferase and aspartate aminotransferase levels was observed with reduction in blood erythrocyte sedimentation rate in all treated animals. Thus, these results could be exploited in the medical field for the formulation of potent antibacterial drugs that cure severe gastrointestinal infections.
Marginalized women and work in 20thand 21st-century british and american literature and media
(Bloomsbury Publishing Plc., 2022) Özkan, Hediye
Marginalized Women and Work in 20th-and 21st-Century British and American Literature and Media examines the intricate relationship between marginalized women and work through critical essays about representations of women’s work in non-canonical literary writings, mass media, and popular culture. Covering a broad range of texts including Paule Marshall’s fiction, Natasha Trethewey’s poetry, and the Netflix series Self Made: Inspired by the Life of Madam C.J. Walker, among others, this collection takes an intersectional approach in order to shed light on the definition and meaning of marginalized women’s work and the value of their labor in the capitalistic economic systems of the twentieth and twenty-first centuries.
Can removing zeros from the stock market index be used to ensure financial stability and sustainability
(Bloomsbury Publishing Plc., 2022) Hamurcu, Çağrı
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Diagnosing a hematopoietic malignancy during shoulder arthroplasty
(Inst. Sci. inf., Univ. Defence in Belgrade, 2022) Orhan, Özlem; Sezgin, Erdem Aras; Tokgöz, Mehmet Ali; Çakmak, Pınar; Kanatlı, Ulunay
Introduction. Determining the cause of shoulder pain is usually a challenge as many problems, such as rheumatoid arthritis, osteoarthritis, osteonecrosis, rotator cuff arthropathy, traumatic arthritis, fractures, conditions of cervical vertebra, and neoplasms, can produce similar symptoms. The diagnosis is usually regarded as incidental, however, chronic lymphocytic leukemia (CLL) diagnosis by the histopathological evaluation performed on lymph nodes excised during a shoulder procedure has not been reported in the literature, to the best of our knowledge. We present a CLL-small lymphocytic lymphoma (SLL) case diagnosed incidentally during reverse shoulder arthroplasty. Case report. A 69-year-old female with a history of left proximal humerus fracture a year prior was presented to our outpatient clinic with left shoulder pain. A proximal humerus non-union was revealed radiographically. The patient underwent reverse shoulder arthroplasty. During surgery, a 2.5 × 1.5 × 1 cm sized lymph node was observed near the left cephalic vein. The lymph node biopsy result was reported to be CLL-SLL. The patient had no early postoperative complications and was discharged two days after. At her final evaluation, she was free of orthopedic complaints and was consulted with the hematology department to receive CLL-SLL treatment. Conclusion. Elderly patients presenting with non-union should be questioned for vague symptoms; lymph nodes surrounding the non-union site should be examined thoroughly. Any suspicious lymphadenopathy encountered during orthopedic surgery should be excised and sent for pathological evaluation.
