Biomaterials a nd their carriers for managing bone disorders
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Tarih
2024
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
CRC Press
Erişim Hakkı
info:eu-repo/semantics/closedAccess
Özet
Bone is often regarded as a prototype for tissue engineering practices with its profound regenerative ability. Developing biological substitutes mimicking the natural composition of the bone and discovering ways to alter the biological pathways of bone regeneration are amongst the most prominent topics in regenerative medicine research. Despite the multitude of in vitro and in vivo research with great potential to improve the management of bone-related disorders, clinical trials on the topic are lagging, partly due to expenses and regulations. Therefore, routine clinical application of promising research may still take years, if not decades. All is not lost however, as there are numerous clinical trials and applications in the field of orthopedics and maxillofacial surgery. This chapter briefly presents an overview of the biomaterials and biomaterial carriers used to reconstruct bone defects as alternatives to natural grafts, utilize mesenchymal progenitor cells with osteogenic potential or platelet-rich plasma, augment the anchorage of inert or bioabsorbable implants, and deliver particular antibiotics to treat osteomyelitis or periprosthetic joint infections as well as anticancer drugs to the bone.
Açıklama
Anahtar Kelimeler
Biomaterials, Carriers for Managing
Kaynak
Emerging Materials and Technologies for Bone Repair and Regeneration
WoS Q Değeri
Scopus Q Değeri
N/A
