The effect of medication and lifestyle factors on global burden of disease and mortality in chronic diseases in OECD countries: the case of type 2 diabetes mellitus

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Date

2024

Journal Title

Journal ISSN

Volume Title

Publisher

Refik Saydam National Public Health Agency (RSNPHA)

Access Rights

info:eu-repo/semantics/openAccess

Abstract

Chronic diseases refer to long-lasting health problems that are generally difficult to treat. The most common chronic diseases include diabetes, heart disease, hypertension, chronic respiratory diseases, and cancer. These diseases are typically associated with lifestyle factors such as genetic predisposition, poor nutrition, insufficient physical activity, excessive smoking, and alcohol consumption. In addition to physical discomfort, chronic diseases also have psychological and social impacts on individuals. The treatment process usually requires long-term management and patient adherence. Therefore, regular medical checkups, healthy lifestyle habits, and proper medication dosage are crucial. The prevalence of chronic diseases is increasing in OECD (Organisation for Economic CoOperation and Development- Ekonomik İşbirliği ve Kalkınma Örgütü) countries, and the impact of drug use and lifestyle factors on the global burden of disease and mortality is becoming increasingly important. Type 2 diabetes is an important example in this context. This study aims to examine the impact of medication use and lifestyle factors in the management of type 2 diabetes mellitus on the global burden of disease and mortality. Methods: The study population includes all OECD countries. Medications used in type 2 diabetes mellitus, alcohol consumption, tobacco consumption, obesity, physical inactivity were used as independent variables; type 2 diabetes-related mortality, type 2 diabetes DALYs (Disability-adjusted life years) were used as dependent variables. Results: Regression analysis showed that lifestyle factors (lnAlc, lnTob, lnObes, lnPInact) and medication use (lnDrug) effected both lnDALY and lnDMort (p<0.05). Conclusion: The effective use of medication and lifestyle changes in the management of type 2 diabetes is an important step in controlling the disease. Therefore, in addition to the use of medication, healthy lifestyle habits should be promoted to prevent and control chronic diseases. These measures can contribute both to improving the health of individuals and to the sustainability of health systems.

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Keywords

Diabetes-related Mortality, Diyabete Bağlı Ölümler, Global Burden of Disease, Küresel Hastalık Yükü, Medication, Sağlıklı Yaşam Tarzı, Tip 2 Diyabet, Type 2 Diabetes, Healthy Lifestyle, İlaç Tedavisi

Journal or Series

Turk Hijyen ve Deneysel Biyoloji Dergisi

WoS Q Value

Scopus Q Value

Volume

81

Issue

4

Citation