Relationship between the Spatial QRS-T angle and Syntax and Gensini Scores in patients with non-ST-elevation Acute Coronary Syndrome

dc.authorid0000-0002-8170-5912
dc.authorid0000-0002-8517-2033
dc.contributor.authorSökmen, Erdoğan
dc.contributor.authorYıldırım, Alp
dc.date.accessioned2025-10-01T11:58:21Z
dc.date.available2025-10-01T11:58:21Z
dc.date.issued2025
dc.departmentTıp Fakültesi
dc.description.abstractBackground: Frontal and spatial QRS-T angles reflect ventricular repolarization heterogeneity and may be associated with coronary artery disease severity. This study aimed to evaluate their relationship with SYNTAX and Gensini scores in non-ST elevation myocardial infarction (NSTMI) patients. Methods: A total of 1188 patients with NSTMI were retrospectively analyzed. Frontal and spatial QRS-T angles were calculated from 12-lead digital ECGs using the Rautaharju method. Correlation, univariate and multivariate linear regression, ROC, and logistic regression analyses were performed to assess their associations with SYNTAX and Gensini scores. Results: The spatial QRS-T angle was independently associated with SYNTAX and Gensini scores in multivariate linear regression, whereas the frontal QRS-T angle showed no significant association. Patients with SYNTAX score >32 had significantly higher spatial QRS-T angles. ROC analysis demonstrated that spatial QRS-T angle >105.2° predicted high SYNTAX scores with an AUC of 0.80. Logistic regression confirmed the spatial angle as an independent predictor of high SYNTAX score (OR: 1.04, 95% CI: 1.02–1.06; p<0.001). Conclusion: The spatial QRS-T angle, but not the frontal angle, is a significant independent predictor of severe coronary artery disease in NSTMI patients. It may serve as a simple, non-invasive ECG marker for identifying patients with high atherosclerotic burden.
dc.identifier.endpage113
dc.identifier.issnSN: 2757-6655 / 2757-6655
dc.identifier.issue3
dc.identifier.startpage103
dc.identifier.urihttps://hdl.handle.net/20.500.12451/14583
dc.identifier.volume5
dc.language.isoen
dc.publisherAksaray Üniversitesi
dc.relation.ispartofAksaray Üniversitesi Tıp Bilimleri Dergisi
dc.relation.publicationcategoryMakale - Uluslararası Hakemli Dergi - Başka Kurum Yazarı
dc.rightsinfo:eu-repo/semantics/openAccess
dc.subjectNon-ST Elevation Myocardial Infarction
dc.subjectSpatial QRS-T angle
dc.subjectFrontal QRS-T Angle
dc.subjectSYNTAX Score
dc.subjectGensini Score
dc.titleRelationship between the Spatial QRS-T angle and Syntax and Gensini Scores in patients with non-ST-elevation Acute Coronary Syndrome
dc.typeArticle

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