Diğer Yayınlar Koleksiyonu
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Item Things to know and latest trends in the design and application of nanoplatforms in cancer treatment(Springer, 2024) Yıldırım, Metin; Acet, Burcu Önal; Dikici, Emrah; Odabaşı, Mehmet; Acet, ÖmürNanotechnology has a crucial potential in cancer treatment. Nowadays, the trend of materials science has also contributed to the development of new nanoscale carrier systems, especially for use in the therapy of cancer patients. Many nanocarriers have been developed and continue to be developed for cancer therapy. Nanocarrier-based systems are widely used in cancer imaging, diagnostics, and therapeutics due to its promising properties and potential to increase therapeutic efficacy. The design and use of nano-based delivery systems for cancer therapy are very promising for the future of cancer therapy. This review article has been presented to the literature in order to display the prominent trends in cancer treatment in recent years. For this purpose, key points in designing an ideal nanoplatforms, the latest important nanocarriers such as liposomes, dendrimers, DNA origami, metallic nanoparticles, responsive, smart, biodegradable and biocompatible nanocarriers, together with recent studies, future perspectives are presented. Graphical Abstract: (Figure presented.).Item Solubility and decomposition of organic compounds in subcritical water(MDPI, 2023) Yabalak, Erdal; Akay, Sema; Kayan, Berkant; Gizir, A. Murat; Yang, YuIn this article, studies on organic solubility and stability in subcritical water reported during the past 25 years have been reviewed. Data on the solubility and decomposition of organic compounds in subcritical water, a green solvent, are needed in environmental remediation, chemistry, chemical engineering, medicine, polymer, food, agriculture, and many other fields. For solubility studies, the experimental systems used to measure solubility, mathematical equations derived and applied for the modeling of the experimentally determined solubility data, and the correlation between the predicated and experimental data have been summarized and discussed. This paper also reviewed organic decomposition under subcritical water conditions. In general, the solubility of organics is significantly enhanced with increasing water temperature. Likewise, the percentage of organic decomposition also increases with higher temperature.Item Dipeptide nanostructures: Synthesis, interactions, advantages and biomedical applications(Elsevier, 2023) Ömür, Acet; Shcharbin, Dzmitry; Zhogla, Victoriya; Kirsanov, Pavel; Halets-Bui, Inessa; Önal Acet, Burcu; Gök, Tuba; Bryszewska, Maria; Odabaşı, MehmetShort peptides are important in the design of self-assembled materials due to their versatility and flexibility. Self-assembled dipeptides, a group of peptide nanostructures, have highly attractive uses in the field of biomedicine. Recently these materials have proved to be important nanostructures because of their biocompatibility, low-cost and simplicity of synthesis, functionality/easy tunability and nano dimensions. Although there are different studies on peptide and protein-based nanostructures, more information about self-assembled nanostructures for dipeptides is still required to discover the advantages, challenges, importance, synthesis, interactions, and applications. This review describes and discusses the self-assembled dipeptide nanostructures especially for biomedical applications.Item Recent developments in polymer-supported ruthenium nanoparticles/complexes for oxidation reactions(Elsevier, 2021) Nasrollahzadeh, Mahmoud; Soleimani, Fahimeh; Bidgoli, Nayyereh Sadat Soheili; Nezafat, Zahra; Orooji, Yasin; Baran, TalatPolymers are extensively used as supports for the fabrication of catalysts. They have many advantages such as high thermal stability, ease of modification, high mechanical strength and large surface area. In recent years, the methods for the preparation of metal nanoparticles and complex based catalysts have been developed to a great extent. The presence of supports in the construction of catalysts prevents the accumulation of metal nanoparticles. In this review, polymer-supported ruthenium (Ru) catalysts (in two complex and nano forms) have been covered as significant catalysts for the oxidation of compounds such as types of alcohols, D-glucose, 5-hydroxymethylfurfural, etc. Oxidation of alcohols is of outstanding importance both in industrial and academic research. The solvent, oxygen pressure and temperature are the significant reaction parameters in the process. The advantages and differences related to the reported polymer-supported Ru catalyst systems have been reviewed, while new progresses, for example, a catalyst system for optimal oxidations, have also been outlined.Item Recent advances in polymer supported palladium complexes as (nano)catalysts for Sonogashira coupling reaction(Elsevier, 2020) Nasrollahzadeh, Mahmoud; Motahharifar, Narjes; Ghorbannezhad, Fatemeh; Soheili Bidgoli, Nayyereh Sadat; Baran, Talat; Varma, Rajender S.Palladium (Pd) complexes supported on the polymers have been widely used in various organic syntheses endeavors because of their thermal stability, high catalytic activities and recyclability. This article provides contemporary advancements in the deployment of polymer-supported Pd complexes (PSP complexes) in Sonogashira coupling reactions (SCR) of halobenzenes with alkynes. Although most of the reports on SCR are focused on aryl iodides, newer methodologies with supported Pd enable the activation of other aryl halides, especially chlorides, which are discussed in this review.
