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A retrospective clinical trial on nasal bone fractures admitted to a level three emergency room
(Annals of Medical Research, 2020) Çayır, Serkan; Mutlu, Hüseyin; Sert, Ekrem Taha
Aim: The anatomical location and protruding structure of the nasal bone can easily lead to fracture as a result of trauma. The high incidence rates have emphasized that the causes, treatments, and complications of these fractures should be investigated. The purpose of this study is to investigate our treatment modalities and complications by reviewing the current information about such fractures. Material and Methods: A total of 582 patients presented with nasal bone fractures between January 2014 and December 2019 were retrospectively analyzed. Examination findings, patient records, and radiological examinations of fractures were analyzed in detail. Results: The age of the patients was between 2 and 83 years (mean age: 33.9 ± 6.11 years). The study included 451 (77.5%) males and 131 (22.5%) females. The most common etiologic factor was assault (35.7%). The most common postoperative complications included deformity (53 patients; 9.1%), nasal congestion (41 patients; 7.1%), and smell disorders (5 patients; 0.9%), with the complications increased with the severity of fracture. Conclusion: Reduction procedures are successfully performed within the first 2 weeks following nasal fractures, and if there is a suspicion of causing deformity in patients under observation, necessary surgical interventions should be performed.
Acil servisimize başvuran hastaların 5 yıllık analizi
(Muğla Sıtkı Koçman Üniversitesi, 2021) Sert, Ekrem Taha; Mutlu, Hüseyin; Yeşildağ, Kerim; Kokulu, Kamil; Sarıtaş, Ayhan
Acil servise başvuran kritik hastalıkların özelliklerinin bilinmesi, en kısa sürede tanı alması ve doğru tedavilerinin başlamasında hayati öneme sahiptir Çalışmamızda acil servise başvuran hastaların demografik ve klinik özelliklerini incelemeyi amaçladık. Ocak 2015 ile Aralık 2019 tarihleri arasında hastanemiz üçüncü basamak acil servisine başvuran tüm erişkin ve çocuk hastalar retrospektif olarak değerlendirildi. Hastaların demografik özellikleri, hastalık tanıları ve yıllara göre başvuru oranları değerlendirildi. Acile servise beş yıl içerisinde başvuran hasta sayısı 2.254.302 olarak tespit edildi. Hastaların %50.9’u erkek ve %49.1’i kadındı ve yaş gruplarına göre başvuru sıklığı değerlendirildiğinden yoğun grubun %26.73 ile 10 yaş ve altı olduğu görüldü. En çok başvuru %51 ile 16:00-24:00 saatleri arasında idi. Hastaların en sık solunum sistemi problemleri(%24,71) ile acile başvurduğu tespit edildi. Acil servise başvuran hastaların %2.24’ü ilgili bölümlere, %0.77’sinin ise yoğun bakım ünitesine yatırıldığı tespit edildi. Acil servislere başvuru oranının yüksek olması beraberinde aşırı hasta yoğunluğuna neden olmaktadır. Acil servise başvuran hasta profilinin belirlenmesi, verilecek hizmet sunumu ve hasta bakım kalitenin artırılmasında faydalı olacaktır.
An effective treatment option for pain caused by urolithiasis: A randomised-controlled trial of local active warming with heat-patch
(Blackwell Publishing Ltd, 2021) Mutlu, Hüseyin; Ertaş, Kasım; Kokulu, Kamil; Sert, Ekrem Taha; Diri, Mehmet Akif; Gül, Murat
Background: There is growing interest in physical medicine treatment options for renal colic. In this study, we aimed to determine whether or not heat-patch treatment with no drug was effective in relieving renal colic. Methods: For this purpose, patients who were diagnosed with renal colic in the emergency department were randomised to have either heat-patch or sham treatment. The Visual Analogue Scale (VAS) scores of renal colic, body temperature (Btemp), and sub-patch skin temperature (Stemp) values were measured at 0, 15, 30, 45, and 60 minutes. In addition, the salvage treatment needs of the groups were compared. Results: The average age of the study group was 30.5 ± 8.3 years and that of the sham group was 31.0 ± 8.2 years (P =.75). According to the baseline VAS score of the patients, 15, 30, 45, and 60 minutes VAS scores significantly decreased in the heat-patch group (P <.001). The Btemp values did not differ significantly between the heat-patch and sham groups. In addition, no statistically significant difference was found between the two groups in terms of Stemp values at 0 and 15 minutes (P =.39 and P =.10, respectively). However, there was a significant difference in the heat-patch group in terms of Stemp values at 30, 45, and 60 minutes compared with the sham group (P <.001). The salvage treatment rates for the heat-patch and sham groups were 11.5% and 31.4%, respectively (P =.01). Conclusion: As non-pharmaceutical treatment, the heat-patch has been shown to be a possible candidate for pain relief in patients with urolithiasis. Further research should concentrate on multicentre and large scale randomised studies.
Anxiety level in pre-hospital emergency medical services personnel during coronavirus disease-2019 pandemic
(Emergency Medicine Physicians Association, 2021) Mutlu, Hüseyin; Sert, Ekrem Taha; Kokulu, Kamil; Sarıtaş, Ayhan
Aim: This study aimed to determine the anxiety level in pre-hospital emergency medical services personnel (PHEMSPs) and investigate the factors that potentially affect the anxiety level during the pandemic. Materials and Methods: This cross-sectional survey was conducted with PHEMSPs during the Coronavirus Disease-2019 (COVID-19) pandemic. A 60-item survey, including socio-demographic characteristics, anxiety-related demographic factors, and State-Trait Anxiety Inventory (STAI) scale scores was used. Results: Among 586 PHEMSPs participating in the study, 50.5% were female, with median age of 30 years. The mean STAI-S value was 42.2, and the median STAI-T value was 48. The anxiety levels of female PHEMSPs (STAI-S=51 and STAI-T=44.14) were higher than male (STAI-S=44 and, STAI-T=40.26). The anxiety level of patients with chronic diseases (STAI-S=56 and, STAI-T=45.77) was significantly higher than those without chronic diseases. State anxiety scores in married individuals (STAI-S=49) were higher than those unmarried individuals. Conclusion: Clearly, people who provide this service should be psychologically healthy to efficiently provide healthcare for the benefit of the people. All types of media assume a great responsibility in reducing the unrest or anxiety that may occur in humans, especially because of their potential to reach many parts of the society.
Artificial intelligence application for identifying toxic plant species: A case of poisoning with Datura stramonium
(Elsevier Ltd, 2024) Kokulu, Kamil; Sert, Ekrem Taha
The management of plant poisonings in the emergency department (ED) presents various challenges. Foremost among these is the identification of the specific botanical species responsible for the toxic effect. In cases of plant poisoning, it is crucial to accurately identify the plant in order to promptly evaluate if it has cardiotoxic, neurotoxic, hepatotoxic, or anticholinergic properties. Furthermore, it is typically not possible to determine the identity of these plants through blood tests conducted in the ED. Case report: An otherwise healthy 23-year-old male patient presented to the ED with symptoms of restlessness, altered mental state, and hallucinations that occurred 2 h after consuming herbal tea. On physical examination, he was tachypneic, tachycardic, and disoriented. The pupils were bilaterally mydriatic. The patient's symptoms were consistent with both sympathomimetic and anticholinergic (antimuscarinic) toxidromes. We were unable to promptly reach a botanist to identify the plant to which the patient had been exposed. Therefore, we employed Google Gemini, an artificial intelligence software, to ascertain the plant's identity. Google Gemini identified the plant we photographed as Datura stramonium, commonly known as jimson weed, which is known to cause anticholinergic toxicity. The botanist we contacted later confirmed that the plant was D. stramonium. The patient's symptoms were alleviated with the use of intravenous diazepam and physostigmine. Conclusion: We propose that the utilization of artificial intelligence applications with visual recognition capabilities could be beneficial for physicians, patients, and foragers of edible wild plants to accurately identify plants and distinguish toxic species.
Carbon monoxide poisoning from Charcoal-Heated Hookah vs Electrically Heated Hookah
(W.B. Saunders, 2024) Kokulu, Kamil; Sert, Ekrem Taha
We have read with great interest the article titled “Waterpipe vs non-Waterpipe carbon monoxide poisoning: Comparison of patient characteristics, clinical presentation, and outcomes” by Abdul-Nabi et al. [1]. There is a limited number of studies in the literature that specifically address this topic [2,3], and we express our gratitude to the authors for their insightful contribution. We would like to highlight several key points related to carbon monoxide (CO) poisoning associated with hookah use.
Characteristic profile of the patients consulted from emergency department to otolaryngology clinic
(Kula Burun Boğaz ve Baş Boyun Cerrahisi Derneği, 2020) Mutlu, Hüseyin Nizam; Sert, Ekrem Taha; Çayır, Serkan; Kokulu, Kamil
Objective: Currently, consultation requests are frequently made from emergency departments to other clinics. The aim of this study is to perform a detailed analysis of the consultation requests from the emergency department to the otolaryngology clinic and to evaluate the case results and the need for consultation. Material and Methods: The files of 743 cases consulted from the emergency room to the otolaryngology clinic between January 2016 and December 2019 were reviewed retrospectively. Reasons for requesting consultation, symptoms and diagnoses of the cases, and procedures performed as a result of the consultation were analyzed in detail. Results: The ages of the patients ranged between 1 and 93 years (mean: 49.7 ± 9.38 years), and there were 354 (47.6%) female and 389 (52.4%) male patients. The most common reason for consultation request was epistaxis (24.5%). As a result of the consultation, 1.6% of all cases underwent emergency surgical operation and 4.9% underwent various surgical procedures under local anesthesia, and 4.2% were hospitalized for medical treatment. Outpatient clinic follow-up was recommended for 381 cases (51.3%), while elective operation was recommended for 125 cases (16.8%). As a result of 119 consultations (16.1%), no otolaryngologic pathology was found and these consultations were considered unnecessary. Conclusion: By having a sufficient number of specialist physicians in emergency departments, evaluating the problems associated with consultations with regular meetings between clinics, and organizing training programs in institutions that train specialist doctors, unnecessary requests for consultations can be reduced.
ChatGPT's ECG interpretations: Sensitivity or specificity? Which matters more in the emergency department
(W.B. Saunders, 2025) Sert, Ekrem Taha; Akay, Muhammed
We read with great interest the article by Zaboli et al. [1], titled “Exploring ChatGPT's potential in ECG interpretation and outcome prediction in the emergency department.” This study provides valuable insights into a critical issue in emergency medicine, where both high patient volumes and the potential consequences of misdiagnoses demand precise and efficient decision-making. By exploring the potential role of ChatGPT, the study contributes significantly to the ongoing dialogue on leveraging artificial intelligence (AI) to enhance diagnostic accuracy and streamline workflows in emergency settings.
Clinical predictors of delayed neurological sequelae in charcoal-burning carbon monoxide poisoning
(W.B. Saunders, 2021) Sert, Ekrem Taha; Kokulu, Kamil; Mutlu, Hüseyin
Background: The main objective of the treatment of acute carbon monoxide (CO) poisoning is to prevent delayed neurological sequelae (DNS). However, today there is still no objective screening tool to identify patients at high risk of developing DNS. The aim of this study was to identify clinical factors that could predict DNS after acute charcoal-burning CO poisoning. Methods: This prospective observational study was conducted from September 1, 2019 to August 31, 2020 in a single academic medical center. Patients older than 18 years of age suffering from charcoal-burning CO poisoning were included in the study. After acute recovery, patients were followed up for six weeks to investigate for DNS development. The clinical predictors of DNS were determined using a multivariate logistic regression model. Results: Of the 217 patients—113 males (52.1%), median age 37.0 (27.5–51.5) years—included, 49 (22.6%) developed DNS. The multivariate logistic regression analysis revealed the independent predictors of DNS as a lower initial Glasgow Coma Scale (GCS) score (adjusted odds ratio (AOR): 0.73, 95% confidence interval (CI): 0.62–0.87), a longer duration of CO exposure (AOR: 2.18, 95% CI: 1.65–2.88), and the presence of acute brain lesions with high signal intensity on diffusion-weighted imaging (AOR: 5.22, 95% CI: 1.50–18.08). The created multivariate regression model predicted DNS development with high accuracy (area under the curve: 0.93, 95% CI: 0.89–0.97). Conclusion: A low initial GCS score, longer exposure to CO and abnormal findings on diffusion-weighted magnetic resonance imaging can assist in the early identification of patients at high risk of DNS development.
Comparison of the effect of two different intravenous methylprednisolone doses on the occurrence time of biphasic reaction
(İnönü Üniversitesi, 2021) Sert, Ekrem Taha; Kokulu, Kamil; Mutlu, Hüseyin; Parlak, İsmail
The aim of this study is to determine the effect of two different doses of methylprednisolone administered in our emergency department (ED) on the elapsed time in biphasic or recurrent anaphylaxis cases. Materials and Methods: The patients with anaphylaxis admitted to the ED were retrospectively analyzed. A total of 82 patients who received methylprednisolone in combination with epinephrine in the ED due to anaphylaxis and who developed biphasic reaction within 48 h after discharge were included in the study. The patients were classified into two groups according to the dose of methylprednisolone administered: 80 mg (Group 1, low-dose) and 120 mg (Group 2, high-dose). The effect of different doses of methylprednisolone on the development time of biphasic reaction was evaluated. Results: Two different doses of IV methylprednisolone administered in the ED did not affect the development time of biphasic reaction (p = 0.24). The biphasic reaction development times were 335 (IQR, 212–950) min in the low-dose group and 520 (IQR, 265– 1150) min in the high-dose group. The earliest development time of biphasic reaction was 125 min (low-dose group) and the latest development time was 2270 min (high-dose group). The relationship between dose and biphasic reaction development times was evaluated using Kaplan–Meier curve. No significant difference was observed between the two groups (p = 0.28). Upon comparing the symptoms in patients’ second admission to the ED due to biphasic reaction, no statistically significant difference was observed in patient symptoms with respect to the dose administered (p > 0.05). Conclusions: Corticosteroids are often used in ED, although there is no definitive evidence that they prevent biphasic reactions. The administration of two different doses of methylprednisolone has no effect on biphasic reaction development time.
Diagnostic value of lateral ankle radiography in achilles tendon rupture
(SAGE Publications Ltd, 2023) Kokulu, Kamil; Altunok, İbrahim; Sert, Ekrem Taha; Özdemir, Serdar; Mutlu, Hüseyin; Akça, Hatice Şeyma
Achilles tendon rupture (ATR) is a common sports injury, but approximately 20% of acute ATR cases are misdiagnosed as ankle sprains at first presentation. This study aimed to investigate the diagnostic value of lateral ankle radiography in the diagnosis of acute ATR. Methods: This was a retrospective case-control study in which the lateral ankle radiographs of patients who presented to the emergency department between January 1, 2015 and December 31, 2019 were examined. The study included a total of 154 patients with acute ATR, who underwent lateral ankle radiography at the presentation and were surgically or magnetic resonance imaging (MRI) confirmed to have ATR in our hospital. The lateral ankle radiographs of the patients were examined by 2 clinicians blinded to clinical data for the following 3 findings: Kager’s fat pad sign, tibio-first metatarsal angle, and tibiocalcaneal angle. The same procedure was repeated for 308 controls who underwent lateral ankle radiography and were diagnosed with ankle sprain.
Effectiveness of clinical risk factors in the detection of central pathology in patients with isolated vertigo
(Elsevier Inc., 2021) Sert, Ekrem Taha; Çayır, Serkan; Mutlu, Hüseyin; Kokulu, Kamil
Background: There is no clinical guidance for the indications of neuroimaging in patients with isolated vertigo. The differential diagnosis of isolated vertigo can be challenging for emergency physicians. Objective: The aim of this study was to identify the risk factors that increase the likelihood of detecting a central pathology in patients who present with isolated vertigo and in whom peripheral vertigo is considered. Methods: Patients imaged using neuroimaging, including diffusion-weighted magnetic resonance imaging (DW-MRI) with head computed tomography (CT), for isolated vertigo over a 3-year period were identified retrospectively. The patients were divided into two groups—a positive neuroimaging group and a negative neuroimaging group—according to the abnormal lesions in the head CT and DW-MRI results. We reviewed the medical records to identify presenting symptoms and signs, vascular risk factors, history of vertigo, medical comorbidities, and diagnostic imaging results (i.e., head CT and DW-MRI). Results: Two hundred and seventy-nine patients were included: 231 in the negative neuroimaging group (82.8%) and 48 in the positive neuroimaging group (17.2%). Univariate and multivariate logistic regression analyses were performed. It was found in the regression analysis that being 65 years or older (odds ratio [OR] 2.53; 95% confidence interval [CI] 1.29–4.96; p = 0.006), having two or more vascular risk factors (OR 2.45; 95% CI 1.10–5.46; p = 0.028), and not responding to the treatment (OR 2.57; 95% CI 1.08–6.14; p = 0.033) increased the likelihood of detecting a pathology in neuroimaging. Conclusions: We suggest that patients unresponsive to ED treatment, 65 years or older, and with two or more vascular risk factors, should alert physicians for central causes and increase the yield of neuroimaging.
Effects of Clinical Frailty Scale Score on Adverse Outcomes and Length of Emergency Department Stay Before Intensive Care Unit Admission
(Elsevier, 2024) Sert, Ekrem Taha; Kokulu, Kamil; Mutlu, Hüseyin; Yortanlı, Betül Çiğdem
Background: Older adults living with frailty who require treatment in hospitals are increasingly seen in emergency departments (EDs). Objective: This study investigated the effects of frailty severity according to the Clinical Frailty Scale (CFS) on adverse outcomes and length of stay in the ED before intensive care unit (ICU) admission. Methods: We conducted this prospective observational study with patients 65 years or older and admitted to the ICU from March 1, 2021 to December 31, 2022. We divided the patients into four groups according to their CFS scores. We determined the effects of frailty severity on length of ED stay and clinical outcomes using logistic regression analysis. Results: Of the 920 patients included in the study, 25.4% were nonfrail, 26.2% had mild frailty, 25.9% had moderate frailty, and 22.5% had severe frailty. In the regression analysis, compared with those who were nonfrail, the length of ED stay was significantly longer for those with moderate frailty (odds ratio [OR] 2.13; 95% confidence interval [CI] 1.63-2.90) or severe frailty (OR 3.32; 95% CI 1.92-3.87), but the result was not significant for those with mild frailty (OR 1.65; 95% CI 1.21-2.45). ICU mortality was significantly higher among patients with mild, moderate, or severe frailty than among those who were nonfrail. Conclusions: We found CFS score to be a predictor of length of ED stay and adverse outcomes. Accordingly, CFS evaluation can provide an idea of the length of ED stay and the likelihood of adverse outcomes.
Etiological characteristics and management of patients with epistaxis in Aksaray
(Annals of Medical Research (Ann Med Res), 2020) Çayır, Serkan; Mutlu, Hüseyin; Sert, Ekrem Taha
Aim: Epistaxis is a common condition in humans, particularly in patients with hypertension, and is one of the most common presenting symptoms in ear, nose, and throat emergency consultation. The present study aimed to examine the treatment and hospitalization characteristics of the patients who presented with epistaxis in Aksaray city and to propose an optimized and updated protocol. Material and Methods: The present study retrospectively evaluated 758 patients who presented with epistaxis to the Training and Research Hospital in Aksaray between January 2016 and February 2020. The patients were analyzed in terms of age, sex, seasonal characteristics, hospitalization rates, pathogenesis of epistaxis, sites of bleeding, and treatments. Results: The study included 349 females (46.1%) and 409 males (53.9%); mean patient age was 60.9 ± 9.3 years (range: 3–89 years). The most common comorbidity was hypertension (47.3%), and the most common site of bleeding was the anterior region including the Kiesselbach’s plexus (88.2%). Nasal packing (58.5%) and electrocauterization (29.9%) were performed in most cases. The treatment success was defined as no instance of re-visit by the patients to the hospital due to nasal bleeding within 24 h after the procedure; the treatment was successful in 698 patients (92.1%). Conclusion: Most cases of epistaxis are successfully treated using endoscopic electrocauterization on an outpatient basis. Hospitalization is indicated if surgical intervention, posterior packing, or embolization is required and if deterioration of general condition is observed. The present study proposes an updated protocol optimized for the management of epistaxis.
Impact of chronic medical conditions on mortality in geriatric trauma, 10-year analysis of a single centre in Turkey
(Taylor & Francis, 2022) Çağlar, Ahmet; Sert, Ekrem Taha; Mutlu, Hüseyin
Background The healthy and active lifestyle adopted by the elderly as a result of improvements in the standards of living may lead to an increase in the risk of injury. Comorbidities increase the risk of posttraumatic complications and mortality. The aim of this study was to investigate the impact of chronic medical conditions (CMCs) on the risk of mortality in geriatric trauma patients. Methods All geriatric trauma patients admitted to emergency department over a 10-year period were retrospectively analysed. Patients were stratified by baseline characteristics, injury severity score (ISS), presence of CMCs, and in-hospital mortality. Multivariate logistic regression was used to determine variables significantly associated with in-hospital mortality. Results 9455 patients included in the study. The median age was 74 (10) years and 57% of them were female. The presence of >= 1 CMC and >= 2 CMCs increased the risk of mortality 5.64 and 2.38 times respectively in mild traumas and 2.67 and 2.59 times respectively in moderate traumas. Age, ISS and penetrating traumas had a significant impact on the risk of mortality in all ISS groups. In severe traumas, only renal disease had an impact on the risk of mortality (OR = 2.58, 95%CI = 1.03-6.43, p = 0.042). All other CMCs, >= 1 CMC, and >= 2 CMCs had no impact on the risk of mortality. Conclusion The presence of CMCs in elderly patients with mild and moderate injuries increases the risk of mortality. Such patients should be diagnosed and treated more quickly and aggressively during the prehospital process and in the hospital.
Lipocalin-type prostaglandin D synthase levels are associated with the severity of pulmonary embolism
(Springer, 2020) Mutlu, Hüseyin; Kokulu, Kamil; Sert, Ekrem Taha; Çağlar, Ahmet
Pulmonary thromboembolism (PTE) is an acute emergency with high mortality and morbidity rates. This study aimed to investigate the importance of Lipocalin-type prostaglandin D synthase (L-PGDS) in predicting mortality and prognosis in PTE. The study prospectively included 90 patients who were admitted to the emergency department and in whom PTE was confirmed by computed tomographic pulmonary angiography as well as 40 healthy volunteers with no disease. L-PGDS levels in the venous blood were measured and compared. Pulmonary embolism severity index (PESI) prognosis scores of all patients and 1-month mortality rate were calculated. There was a statistically significant difference between the L-PGDS levels of the patient and control groups (P?=?0.024), and 1-month mortality of patients diagnosed with PTE was 20% (n?=?18). Furthermore, the patients were divided into two groups: patients deceased within 1 month following the diagnosis and survivors. L-PGDS levels of the deceased patients were significantly higher than those of the survivors (P?
Predictive Value of Ionized Calcium Level for Sinus Rhythm Conversion in Adenosine Treatment for Paroxysmal Supraventricular Tachycardia
(Elsevier Inc., 2025) Sert, Ekrem Taha; Kokulu, Kamil; Mutlu, Hüseyin; Gönen, Mustafa Önder; Sert, Zekiye Soykan
Background: Paroxysmal supraventricular tachycardia (SVT) is a recurrent tachydysrhythmia that often leads to emergency department (ED) visits and is commonly treated with intravenous adenosine. Objective: The objective of this paper is to evaluate the relationship between the initial ionized calcium (iCa) level and the achievement of normal sinus rhythm following 6 mg adenosine administration in patients with SVT. Methods: This retrospective, single-center study was conducted in the ED from 2019 to 2023 and included consecutive adult patients diagnosed with SVT who received adenosine treatment. The patients were categorized into two groups based on their response to adenosine treatment. The receiver operating characteristic (ROC) curves were constructed to evaluate the effectiveness of iCa levels in predicting conversion to sinus rhythm. Results: A total of 326 patients were analyzed. The mean iCa level in patients who achieved a sinus rhythm after the initial 6-mg dose was 1.13 ± 0.08 mmol/L, as compared to 1.03 ± 0.11 mmol/L in those who did not respond to this dose, indicating a statistically significant difference (mean difference [95% confidence interval (CI)]: −0.101 [−0.12 to −0.07]). The area under the ROC curve was calculated to be 0.803 (95% CI: 0.752–0.854). An iCa cut-off value of 1.14 mmol/L was determined to be significant for the prediction of achieving sinus rhythm, with a sensitivity of 64.75% (95% CI: 55.6–73.2) and a specificity of 87.75% (95% CI: 83.6–92.7). Conclusion: Our study suggests that the iCa level may be a useful parameter for predicting the response to the 6 mg adenosine dose in patients with SVT.
Predictors of adverse perinatal outcomes in women at 40 weeks or more of pregnancy
(Publishing Office of the University of Rzeszow, 2023) Sert, Zekiye Soykan; Evren Dilmaç, Ayşegül; Alkan, Ender; Sert, Ekrem Taha
Introduction and aim. To evaluate the clinical features of women at ?40 weeks of pregnancy and the utility of obstetric Doppler indices in predicting adverse perinatal outcomes in these pregnancies. Material and methods. This prospective study was conducted at a single academic medical center between 2020 and 2022. Women aged 18 years and older with no risk factors who were at ?40 weeks of pregnancy and delivered their babies in our hospital were included in the study. The fetal biometry, placental maturity grading, and doppler velocytometry indices of the pregnant women were evaluated. The cases were divided into two groups according to the development of adverse perinatal outcomes. The relationship between clinical features and adverse perinatal outcomes was evaluated. Results. Adverse perinatal outcomes developed in 19.6% (42) of the 214 cases. The multiple logistic regression analysis was performed to identify factors affecting perinatal outcomes. Accordingly, a maternal age of ?35 years (odds ratio [OR]: 1.74, 95% confidence interval [CI]: 1.29-3.96, p=0.038), nulliparity (OR: 1.42, 95% CI: 1.13-4.63, p=0.040), and grade 3 placental calcification (OR: 1.98, 95% CI: 1.11-4.53, p=0.029) were independent predictors of adverse perinatal outcomes. Conclusion. Care should be taken in terms of adverse perinatal outcomes in the presence of nulliparity, a maternal age of ?35 years, and grade 3 placental calcification in ?40 week pregnancies.
Predictors of hospitalization in patients presenting to emergency department with an acute exacerbation of COPD ? a single-center study in Turkey
(Publishing Office of the University of Rzeszow, 2023) Sanalp Menekşe, Tuğba; Sert, Ekrem Taha
Introduction and aim. In this study, we evaluated parameters that might be associated with hospitalization in patients admitted to the emergency department (ED) with an acute exacerbation of chronic obstructive pulmonary disease (AECOPD). Material and methods. Patients with COPD who presented to ED due to AECOPD between January 1, 2020 and December 31, 2021 were included in the study. Patient data were obtained from the hospital database. Univariable and multivariable logistic regression methods were used to identify the relationship between hospitalization and clinical parameters. Results. The study included 237 patients divided into two groups: inpatients (n=124) and outpatients (n=113). We found significant differences between the two groups in terms of temperature, oxygen saturation, respiratory rate, C-reactive protein, white blood cell count, procalcitonin, albumin, arterial blood pH, pCO2, and non-invasive mechanical ventilation (NIMV) requirement. Multivariable logistic regression analysis showed that body temperature [odds ratio (OR):1.62;95% confidence interval (CI):1.21–4.91; p<0.001], oxygen saturation (OR:0.73, 95% CI:0.39-0.94, p<0.001), respiratory rate (OR:1.96; 95% CI: 1.07–6.14; p<0.001), albumin (OR:0.71; 95% CI:0.41–0.93; p=0.042), procalcitonin (OR:2.93; 95% CI:1.22–4.84; p<0.001), arterial blood pH (OR:0.78; 95% CI:0.29-0.91; p=0.038), pCO2 (OR:2.45; 95% CI:1.24–4.65; p<0.001), and NIMV requirement (OR:2.31; 95% CI:1.41-5.13; p<0.001) were the independent predictors of hospitalization. Conclusion. Our findings may help identify patients who will require hospitalization at an early stage.
Predictors of obstetric complications following traumatic injuries in pregnancy
(W.B. Saunders, 2021) Soykan Sert, Zekiye; Sert, Ekrem Taha; Kokulu, Kamil
Background: After a traumatic injury, the provision of appropriate, timely care to pregnant women jury is crucial for the health of both the mother and fetus. The aim of this study was to identify risk factors predicting post-traumatic obstetric complications in pregnant women who presented to the emergency department (ED) with traumatic injuries. Methods: We conducted a retrospective cohort study of pregnant women aged 18 y and older who were admitted to the trauma unit of our ED between 2017 and 2020. The data collected included maternal demographics, trauma mechanism, and pregnancy outcome. The patients were divided into two subgroups according to the presence or absence of trauma-related complications, and clinical features were compared between the two groups. Results: In total, 241 pregnant trauma patients were included in the study. The mean maternal age was 26.1 ± 4.4 y, and the mean gestational age the time of the trauma was 28.4 ± 6.8 wk. In the study, 17.8% (43/241) of patients experienced obstetric-related complications within the first 24 h post-trauma. The risk factors associated with obstetric complications were aged older than 35 y (odds ratio [OR] = 5.31,95% confidence interval [CI]: 1.77–15.96, p = 0.003), third trimester trauma (OR = 2.41,95% CI:1.14–5.12, p = 0.021), and abnormal obstetric ultrasonography (OR = 6.25,95% CI:2.03–19.22, p = 0.001). Conclusion: Among pregnant patients who present to the ED after a traumatic injury, advanced maternal age, trauma in the third trimester, and abnormal obstetric ultrasonography findings should alert physicians to the possibility of post-traumatic complications (within the first 24 h after trauma) and the need for close monitoring.

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