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  • Küçük Resim
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    Increased epicardial adipose tissue thickness is associated with angiographic thrombus burden in the patients with non-ST-segment elevation myocardial infarction
    (SAGE Publications Inc., 2015) Bakırcı, Eftal Murat; De?irmenci, Hüsnü; Duman, Hakan; İnci, Sinan; Hamur, Hikmet; Büyüklü, Mutlu; Ceyhun, Gökhan; Topal, Ergün
    We aimed to evaluate the relation among epicardial adipose tissue (EAT) thickness, angiographic presence of thrombus, and the no-reflow in the patients with non-ST-segment elevation myocardial infarction undergoing primary percutaneous coronary intervention. The study population consisted of 229 patients. The EAT thickness and neutrophil to lymphocyte ratio (NLR) were significantly higher in the patients with coronary thrombus than in those without coronary thrombus (6.1 ± 1.1 vs 5.1 ± 1.3 mm, P <.001 and 3.4 ± 0.9 vs 2.5 ± 0.7, P <.001, respectively) and in the patients with no-reflow compared to patients with reflow. The EAT thickness was found to be correlated positively with the degree of the thrombus burden, NLR, and waist circumference and negatively with high-density lipoprotein cholesterol. Multivariate logistic regression analysis demonstrated that EAT thickness and NLR independently predicted coronary thrombus formation and no-reflow. We have suggested that EAT can play an important role in the pathophysiology of coronary thrombus formation and the no-reflow. © SAGE Publications.
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    The effects of successful percutaneous mitral balloon valvuloplasty on acute and intermediate term aortic stiffness
    (Blackwell Publishing, 2015) İnci, Sinan; Nar, Gökay; Erol, Mustafa Kemal; Demirelli, Selami; Duman, Hakan; Serdar, Serkan; Erol, Fatih
    Aim The aim of this study was to evaluate the effects of percutaneous mitral balloon valvuloplasty (PMBV) on short- and intermediate-term aortic stiffness in patients with mitral stenosis. Materials and Methods This prospective study included 56 patients with critical mitral stenosis in normal sinus rhythm (68% female; mean age: 42 ± 11 years) and 37 healthy controls. Aortic stiffness was measured using transthoracic echocardiography before PMBV, and 24-48 hours and 1 year post procedure. Results Aortic strain and distensibility were significantly higher in the patients with mitral stenosis, both after PMBV and 1 year post procedure, whereas the aortic stiffness index (ASI) was significantly lower. There was also a significant decrease in mitral mean gradient (MMG) and systolic pulmonary artery pressure (sPAP) after PMBV, based on echocardiography and catheterization. Mitral valve area (MVA) significantly increased after PMBV. There was a significant correlation between change in ?MVA and ?MMG and aortic elastic properties. There was a significantly negative correlation between the ?MVA and ?? aortic stiffness (r = -0.62, P < 0.001), and a significantly positive correlation between ?MMG and ?ASI (r = 0.60, P < 0.001). Conclusion Mitral valve stenosis was associated with impaired aortic stiffness and following PMBV, aortic stiffness decreased during both the acute period and the intermediate period. © 2014, Wiley Periodicals, Inc.