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Sıçan Dalak Dokusunda Akrilamidin İndüklediği Oksidatif Stres, İnflamasyona ve Apoptoza Karşı Morinin Koruyucu Etkileri: Biyokimyasal ve Histopatolojik Bir Yaklaşım

Akaras, Nurhan; Kandemir, Fatih Mehmet; Şimşek, Hasan; Küçükler, Sefa; Oğuz Kabayel, Rabia (Mustafa İSSİ, 2023)

Akrilamid (AKR), yaygın endüstri kullanımının yanı sıra yüksek karbonhidrat içerikli gıda maddelerinin ısı kaynaklı işlemleri (kavurma, fırınlama ve kızartma) sırasında oluşan sitotoksik ve kanserojen etkilere sahip kimyasal ...

Carvacrol Reduces Mercuric Chloride-Induced Testicular Toxicity by Regulating Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histopathological Changes

Şimşek, Hasan; Gür, Cihan; Küçükler, Sefa; İleritürk, Mustafa; Akaras, Nurhan; Öz, Mehmet; Kandemir, Fatih Mehmet (Springer, 2023)

Mercuric chloride (HgCl2) is a heavy metal that is toxic to the human body. Carvacrol (CAR) is a flavonoid found naturally in plants and has many biological and pharmacological activities including anti-inflammatory, ...

Effects of Bromelain on Oxidative Stress and Lung Tissue Histopathology in an Experimental Rat Sepsis Model

Akaras, Nurhan; Toktay, Erdem; Şimsek, Hasan; Celep Aydemir, Nevra; Yüce, Neslihan (Afyon Kocatepe University, 2023)

Sepsis is an inflammatory syndrome that targets the lung tissue. Bromelain (BRO) is an enzyme complex known for its anti-inflammatory properties. In this study, the protective effect of BRO on lung injury due to sepsis ...

Effects of Quercetin on Cypermethrin-Induced Stomach Injury: The Role of Oxidative Stress, Inflammation, and Apoptosis

Akaras, Nurhan; Gür, Cihan; Şimşek, Hasan; Tuncer, Sibel Çiğdem (Gümüşhane Üniversitesi, 2023)

This study was conducted to investigate the effects of quercetin (QUE) on cypermethrin (CYP) induced gastrotoxicity in rats. 35 Sprague-Dawley rats were randomly divided into five groups, 7 in each group. In the study, 25 ...