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Investigation of the effects of berberine on bortezomib-induced sciatic nerve and spinal cord damage in rats through pathways involved in oxidative stress and neuro-inflammation

Yardım, Ahmet; Gür, Cihan; Çomaklı, Selim; Özdemir, Selçuk; Küçükler, Sefa; Çelik, Hamit; Kandemir, Fatih Mehmet (Elsevier B.V., 2022)

Bortezomib (BTZ), a proteasome inhibitor, causes dose-limiting peripheral neuropathy in humans. Berberine (BBR), which has various biological and pharmacological properties, is known to have neuroprotective properties. The ...

Neuroprotective effects of 18 beta-glycyrrhetinic acid against bisphenol A-induced neurotoxicity in rats: involvement of neuronal apoptosis, endoplasmic reticulum stress and JAK1/STAT1 signaling pathway

Çağlayan, Cüneyt; Kandemir, Fatih Mehmet; Ayna, Adnan; Gür, Cihan; Küçükler, Sefa; Darendelioğlu, Ekrem (Springer, 2022)

The exposure to bisphenol A (BPA) is inevitable owing to its common use in the production of polycarbonate plastics. Studies to reduce side effects are gaining importance since BPA causes severe toxicities in important ...