Aksaray Üniversitesi Kurumsal Akademik Arşivi
DSpace@Aksaray, Aksaray Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
The investigation of drum height effects on masonry domes
(Techno-Press, 2025) Fırat, Fatih K.; Tanrıverdi, Şükran
In this study, the effects of drum height on masonry dome behavior were examined experimentally and numerically by taking into account the domes with and without windows. Within the scope of the study, a total of eight domes, two of which were references (without drums) and six with different drum heights, were tested. One of the references was produced without windows and the other with windows. With window dome test elements having a drum height of 300 mm and 400 mm and windowless dome test elements with a drum height in the range of 100 mm, 200 mm, 300 mm, and 400 mm were examined. Numerical modeling of experimentally tested dome elements using the LUSAS analysis program was also examined and the experimental results were compared with the numerical results. As a result of the study, it was observed that the height of the drum significantly affected the load carrying capacity and horizontal displacement of the domes. It was determined that the lowest height drum application increased the load-carrying capacity of the dome by about 30% according to the drum-free reference test element. As the drum height increased, the load-carrying capacity and rigidity of the dome increased significantly, and the horizontal displacements decreased.
High nuclear genetic diversity of Birecik semi-wild population of endangered Bald Ibis (Geronticus eremita) from Turkey
(Resilience Alliance, 2025) Çakmak, Emel; Pekşen, Çiğdem Akın; Boran, Beril; Hatipoğlu, Taner; Bilgin, C. CanÇakmak
The Northern Bald Ibis (Geronticus eremita) is an endangered species. The western population is estimated to be approximately 700 individuals, located in the Souss Massa region of Morocco. In contrast, the eastern population, now semi-wild, is approximately 300 birds, situated in Birecik, Turkey. Recent reintroduction attempts in Europe have relied exclusively on captive populations derived from the western population and have been accompanied by research on their genetic structure and diversity. However, to date there has been no comprehensive study of a similar nature on the eastern population. In this study, we used five polymorphic microsatellite markers that are specific to the Bald Ibis to investigate the genetic diversity in 100 individuals of the Birecik population. We further sequenced the mitochondrial ND5 fragment in 46 adult individuals in order to reveal genetic differences between the eastern and western populations. Despite the limited number of founder individuals, the nuclear diversity of the Birecik population exhibited a high level of diversity, as measured by allelic richness and expected heterozygosity. However, mtDNA ND5 sequencing revealed a single haplotype (eastern haplotype 1) in all individuals of the eastern population, which differs from the haplotype (western haplotype 1) found in the western population by a single nucleotide. A specific mutation in mtDNA haplotypes, different migratory behavior, and highly restricted gene flow resulting from a long period of breeding as a semi-wild population, combined with geographical isolation, suggest that the eastern population (now only represented by the Birecik semi-wild population) is distinct from the western population. This unexpectedly high genetic diversity indicates the Birecik semi-wild population could act as the source population for reintroduction elsewhere.
RNA-Seq of Chicken Embryo Liver Reveals Transcriptional Pathways Influenced by Egg Formaldehyde Treatment
(Multidisciplinary Digital Publishing Institute (MDPI), 2025) Özdemir, Mustafa; Sajid, Ghulam Asghar; Büyükkılıç Beyzi, Selma; Kızılaslan, Mehmet; Arzık, Yunus; Yalçın, Servet; White, Stephen N.; Çınar, Mehmet Ulaş
Hatchery fumigation is recognized as a crucial step to control microbial bloom in the environment, and formaldehyde is one of the most widely used disinfectants to ensure successful hatchability and healthy production. While many of the benefits are thought to be derived from disinfectant properties, it is possible that additional host gene and genetic pathway modulation could contribute to these outcomes. The current study aimed to capture the in ovo transcriptional response of liver tissue to formaldehyde treatment. Methods: Chick embryos were subjected to formaldehyde fumigation treatment for 25 min at 24–25 °C and 75% relative humidity, keeping a control group as untreated. On the 18th day of incubation at 37.8 °C and 58–63% humidity, eggs were broken, and liver tissue was obtained for RNA isolation, cDNA library preparation, and RNA sequencing. Results: Bioinformatics analysis revealed 908 significant differentially expressed genes (DEGs), among which 814 were known genes and 94 were novel genes. A total of 672 DEGs were upregulated, whereas 236 genes were downregulated in response to FA treatment. Of the 94 novel genes, 80 were upregulated. Key DEGs, associated QTLs, and transcription factors were involved in immuno-inflammatory responses, oxidative stress, epigenetic modification, and cellular adaptation-related activities. Further research should focus on biological validation of key DEGs to clarify their roles, pathways, and relationships to FA treatment. Conclusions: Overall, these findings (1) provide critical molecular detail as a first step towards genetic selection to improve formaldehyde treatment response and effectiveness, and (2) provide DEG signatures for FA treatment as a reference against which to compare other interventions to achieve hatchability and production benefits.
Estrus synchronization using progesterone+different gonadotropins or flushing+ram effect in the breeding season in sheep
(Biblioteca Universidad de Cordoba, 2025) Kırbaş, Mesut; Köse, Mehmet; Bülbül, Bülent; Dursun, Şükrü; Demirci, Uğur; Erduran, Hakan; Sarı, Deniz
. The effect of different doses of Equine Chorionic Gonadotropin (eCG)or a dose of folliclestimulating hormone (FSH) in a progesterone-based estrus synchronization protocol or flushing+ram effect on fertility in the breeding season were examined on Konya Merino ewes. Materials and methods. Ewes were divided into six groups. Estrus of ewes in eCG-300, eCG-500, eCG-700, and FSH-10 groups was synchronized with an intravaginal sponge containing progesterone (Chronogest, 20 mg flugestone acetate, Intervet, Türkiye 20 mg)-derived for 12 days, and PGF2α injected one day before sponge removal. eCG-300, eCG-500, and eCG-700 groups received 300, 500, or 700 IU of eCG, respectively, at the time of PGF2α injection while FSH-10 group received 10 IU of FSH with sponge removal. In these four groups, estrus was detected for 5 days following sponge removal. Flushing+ram effect (F+RE) group ewes received dietary supplements for 28 days and ram effect for 14 days before the start of the mating period and were monitored for estrus for 4 weeks later. Control ewes monitored for estrus for two months without any treatment. Results. Birth rate was higher in F+RE group than eCG-500 and FSH-10 groups (p<0.05). Litter size was higher in eCG-700 group than F+RE and control groups (p<0.05). Fecundity was higher in eCG-700 group than FSH-10 group (p<0.05). Conclusions. 300 IU eCG at the end of progesterone application was sufficient to induce multiple lambing during the breeding season. Moreover, to increase lamb production should be taken necessary management measures for improve survival to weaning of multiple-born lambs.
Differences in foot pressure distribution of males with and without basketball training in early adolescence
(MRE Press, 2025) Kırıkoğlu, Nagihan; Pekel, Aylin Özge; Ceylan, Tülay; Eliöz, Murat; Yavaşoğlu, Belma; Beykümül, Ayşegül; Kurt, Kemal Arda; Çalışan, Hande Yazıcıoğlu; Baykal, Cihan; Karaman, Merve; Türkoğlu, Hayati; Ceylan, Levent
In this study, the Rsscan V9 (RsScan International, Olen, Belçika) foot scanning system was used to determine the potential foot pressure distribution and foot contact times of individuals in early adolescence who did not receive sports training and those who received regular basketball training. Methods: The study involved 120 adolescent volunteers aged 11–14 years of which 60 did not receive sports training, and the other 60 received basketball training in Ankara for at least two years. The socio-demographic data of the study participants were documented. The foot pressure analyses were carried out in both fixed and moving postures. Results: When pressure values were compared between adolescents with and without basketball training, statistically significant differences were found between Q1 (left forefoot pressure) and Q2 (right forefoot pressure) values. Specifically the mean value (p < 0.05) of Q2 (right forefoot pressure) variable was higher in basketball participants compared to non-athletes. In non-athletes, Q1 (left forefoot pressure) (p < 0.05) was significantly higher than in participants who received basketball training. Similarly, with regard to the left forefoot pressure duration (left ms) variable, participants with basketball training showed significantly higher mean scores than non-athletes (p < 0.001). The findings revealed that there were differences in pressure imbalances and ground contact times between basketball players and non-players. Conclusions: If not controlled regularly, pressure imbalances can lead to serious discomfort in the feet, knees, hips and lower back, and serious injuries can be prevented if detected early. Minor injuries that develop due to repetitive movements and stress on joints from years of training can be treated early, and preventive applications can becarried out by recognising potential injuries. For this reason, it is recommended that basketball players have a regular foot pressure analysis carried out at the start of the season.
