Search
Now showing items 1-10 of 10
Zingerone reduces sodium arsenite-induced nephrotoxicity by regulating oxidative stress, inflammation, apoptosis and histopathological changes
(Elsevier, 2023)
Arsenic is widely available in the environment and arsenic toxicity is a public health problem of serious concern worldwide. Zingerone is a promising phytochemical with various pharmacological effects. In this study, the ...
Effect of syringic acid on oxidative stress, autophagy, apoptosis, inflammation pathways against testicular damage induced by lead acetate.
(Elsevier GmbH, 2023)
Heavy metals are one of the environmental pollutants. Lead (Pb) is one of the most common of these heavy metals. In this study, it was aimed at investigating the effects of syringic acid (SA) against testicular toxicity ...
Beneficial effects of Chrysin on Cadmium-induced nephrotoxicity in rats: Modulating the levels of Nrf2/HO-1, RAGE/NLRP3, and Caspase-3/Bax/Bcl-2 signaling pathways
(Elsevier B.V., 2023)
Cadmium (Cd) is a toxic heavy metal that targets the kidney directly in the body. Chrysin (CHR) is a natural flavonoid with many properties such as antioxidant, anti-inflammatory and anti-apoptotic. The current study ...
Protective effects of sinapic acid against lead acetate-induced nephrotoxicity: a multi-biomarker approach
(Springer Science and Business Media Deutschland GmbH, 2023)
Lead acetate (PbAc) is one of the top five most dangerous toxic heavy metals, particularly leading to kidney damage and posing serious health risks in both humans and animals. Sinapic acid (SNP) is a naturally occurring ...
Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum stress
(Elsevier Inc., 2023)
Paclitaxel (PTX) is widely used to treat a number of malignancies, although it has toxic side effects. Hesperidin (HES) has a wide range of biological and pharmacological properties, including anti-inflammatory and antioxidant ...
Anti-oxidant, Anti-inflammatory, and Anti-apoptotic Effects of Rutin in Spleen Toxicity Induced by Sodium Valproate in Rats
(Bingöl Üniversitesi Fen Bilimleri Enstitüsü, 2023)
Long-term exposure to sodium valproate, an anti-epileptic drug, causes toxic effects in tissues, especially by increasing oxidative stress and inflammation. Rutin is a flavanoid with anti- oxidant, anti-inflammatory and ...
Sıçanlarda sodyum valproat kaynaklı mide hasarı üzerine rutin’in oksidatif stres, inflamasyon ve apoptoz üzerindeki koruyucu etkilerinin araştırılması
(Süleyman Demirel Üniversitesi, 2023)
Sodyum valproat, antiepileptik ilaçlardan en yaygın kullanılanlardan birisi olup uzun süreli maruziyet so- nucunda toksik etkilidir. Uzun süreli sodyum valproat maruziyeti dokularda özellikle oksidatif stres ve infla- ...
Sıçanlarda İfosfamid ile Oluşturulmuş Mide Hasarında Morinin Etkilerinin Histopatolojik ve Biyokimyasal Olarak İncelenmesi
(Mustafa İSSİ, 2023)
Bu çalışmada, sıçanlarda deneysel ifosfamid (IFO) uygulamasının neden olduğu mide toksisitesi üzerine morinin (MOR) etkilerinin belirlenmesi amaçlandı. Bu amaçla deney hayvanları beş gruba (n=7) ayrıldı. Gruplar kontrol, ...
Sıçan Dalak Dokusunda Akrilamidin İndüklediği Oksidatif Stres, İnflamasyona ve Apoptoza Karşı Morinin Koruyucu Etkileri: Biyokimyasal ve Histopatolojik Bir Yaklaşım
(Mustafa İSSİ, 2023)
Akrilamid (AKR), yaygın endüstri kullanımının yanı sıra yüksek karbonhidrat içerikli gıda maddelerinin ısı kaynaklı işlemleri (kavurma, fırınlama ve kızartma) sırasında oluşan sitotoksik ve kanserojen etkilere sahip kimyasal ...
Carvacrol Reduces Mercuric Chloride-Induced Testicular Toxicity by Regulating Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histopathological Changes
(Springer, 2023)
Mercuric chloride (HgCl2) is a heavy metal that is toxic to the human body. Carvacrol (CAR) is a flavonoid found naturally in plants and has many biological and pharmacological activities including anti-inflammatory, ...
