Browsing by Author "Tuncer, Sibel Çiğdem"
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Abamektin kaynaklı mide toksisitesinde hesperidinin oksidatif stres, inflamasyon ve apoptoz üzerindeki koruyucu etkisi
Tuncer, Sibel Çiğdem; Gür, Cihan; Şimşek, Hasan; Kandemir, Fatih Mehmet (Ayşe SURUÇ, 2024)Abamektin günümüzde tarım endüstrisinde çok fazla kullanılan bir pestisit türü olup uzun süreli maruziyet sonucunda toksik etkilere sahiptir. Uzun süreli abamektin maruziyeti sonucunda özellikle oksidatif stres ilişkili ... -
Assessment of micronutrient intakes, anxiety states and risk factors affecting disease development in individuals with hypothyroidism
Uçar, Esra; Alim, Nural Erzurum; Tuncer, Sibel Çiğdem; Korkmaz, Özlem Zekiye (Pontificia Universidade Catolica de Campinas, 2024)This study aimed to assessment the risk factors affecting development of hypothyroidism and to examine the selected dietary micronutrient intakes of primary hypothyroidism, subclinical hypothyroidism and euthyroid individuals ... -
C-reactive protein to albumin ratio: Is a new parameter for the disease severity in patients with psoriasis vulgaris?
Kemeriz, Funda; Tuǧrul, Burcu; Tuncer, Sibel Çiğdem (Wolters Kluwer Medknow Publications, 2020)Background: C-reactive protein to albumin ratio (CAR) is an inflammatory marker that is considered to have prognostic value in many inflammatory diseases. Objectives: In this study, we aimed to investigate whether there ... -
Carvacrol reduces abnormal and dead sperm counts by attenuating sodium arsenite-induced oxidative stress, inflammation, apoptosis, and autophagy in the testicular tissues of rats
Gür, Cihan; Akarsu, Serkan Ali; Akaras, Nurhan; Tuncer, Sibel Çiğdem (Wiley, 2023)Arsenic (As) is a highly toxic metalloid. Carvacrol (CAR) is the active ingredient of Lamiaceae plants and has various biological and pharmacological properties. The present study investigated the protective effects of ... -
Comparison of hormone profile and systemic inflammation in patients presenting with sexual dysfunction: Which is important
Demirci, Aykut; Özgür, Berat Cem; Tuncer, Sibel Çiğdem (Ediciones Doyma, S.L., 2021)Introduction: Erectile dysfunction (ED) is the inability to achieve or maintain erection sufficient for satisfactory sexual performance. Although the definition is well known, there are controversial issues about the effects ... -
Doğal Biyoaktif Bileşenlerin iNOS Aktivitesi Üzerine Etkisinin in-Sliko Olarak İncelenmesi
Göktaş, Fadime; Karataş, Mehmet; Tuncer, Sibel Çiğdem; Tekin Karacaer, Neslihan (Aksaray Üniversitesi, 2023)Amaç: Nitrik oksit sentazın indüklenebilir izoformu (iNOS) makrofajlar başta olmak üzere pek çok hücrede sentezlenir ve immün yanıttan sorumludur. iNOS ekspresyonunun ve dolayısıyla NO üretiminin yararlı antiviral, ... -
The effect of COVID-19 pandemic on acute appendicitis and negative laparotomy
Öztürk, Ayşe Betül; Kılıçaslan, Cengiz; Tuncer, Sibel Çiğdem; Ordu, Melike (Selçuk Üniversitesi, 2023)Emergency service referrals frequently depend on non-urgent problems which are easy to solve without emergency services. Emergency services should be used effectively to raise service quality, patient and personnel ... -
Effects of chrysin in cadmium-induced testicular toxicity in the rat; role of multi-pathway regulation
Tuncer, Sibel Çiğdem; Küçükler, Sefa; Gür, Cihan; Aygörmez, Serpil; Kandemir, Fatih Mehmet (Springer Science and Business Media B.V., 2023)Cadmium (Cd) is a strong toxic agent and causes serious damage to testicular tissues. Chrysin (CHR) is a natural flavonoid with many effective properties, especially antioxidant, anti-inflammatory and anti-apoptotic ... -
Effects of Quercetin on Cypermethrin-Induced Stomach Injury: The Role of Oxidative Stress, Inflammation, and Apoptosis
Akaras, Nurhan; Gür, Cihan; Şimşek, Hasan; Tuncer, Sibel Çiğdem (Gümüşhane Üniversitesi, 2023)This study was conducted to investigate the effects of quercetin (QUE) on cypermethrin (CYP) induced gastrotoxicity in rats. 35 Sprague-Dawley rats were randomly divided into five groups, 7 in each group. In the study, 25 ... -
Effects of sinapic acid on lead acetate-induced oxidative stress, apoptosis and inflammation in testicular tissue
Tuncer, Sibel Çiğdem; Akarsu, Serkan Ali; Küçükler, Sefa; Gür, Cihan; Kandemir, Fatih Mehmet (John Wiley and Sons Inc, 2023)In this study, the effect of lead acetate (PbAc) and sinapic acid (SNP) administration on oxidative stress, apoptosis, inflammation, sperm quality and histopathology in testicular tissue of rats was tried to be determined. ... -
Evaluation of 25-hydroxy vitamin D levels and disease severity in patients with acne vulgaris
Kemeriz, Funda; Tuncer, Sibel Çiğdem; Acar, Emine Müge; Tuǧrul, Burcu (Blackwell Publishing Inc., 2020)Acne vulgaris is a multifactorial skin disorder. Many etiological factors are speculated to contribute to the pathogenesis of acne, one of these is vitamin D deficiency. Previous studies reported contradictory results about ... -
Evaluation of dynamic thiol-disulfide homeostasis and ischemia-modified albumin levels in patients with chronic lymphocytic leukemia
Erdal, Hüseyin; Çiftçiler, Rafiye; Tuncer, Sibel Çiğdem; Özcan, Oğuzhan (BMJ Publishing Group, 2023)This is the first study to evaluate both the dynamic thiol-disulfide homeostasis and ischemia-modified albumin (IMA) levels in patients with chronic lymphocytic leukemia (CLL). Twenty-nine patients with CLL and 20 controls ... -
Galectin-3 levels in school aged children with autism spectrum disorder
Artık, Abdülbaki; Kocaman, Orhan; Kara, Halil; Tuncer, Sibel Çiğdem (Taylor and Francis Ltd., 2023)Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders with underlying pathogenesis and etiological factors not fully understood. We assumed that galectin-3, which is also linked with inflammatory ... -
The incidence of biliary sludge in first trimester pregnancies with hyperemesis gravidarum and its effect on the course of hyperemesis gravidarum
Sağlam, Aylin; Derwig, Iris; Sezik, Mekin; Tuncer, Sibel Çiğdem; Özçil, Mustafa D.; Kasap, Burcu; Mısırlıoğlu, Mesut; Alkan, Ender; Özkan, Namık (Taylor & Francis, 2022)Pregnancy is one of the risk factors for biliary sludge (BS) formation. In this cross-sectional study, a total of 959 pregnant women were included. Serum aspartate aminotransferase, alanine aminotransferase, sodium, ... -
Predictive Role of Hematological Markers on Pediatric Appendicitis: Still a Mystery
Öztürk, Ayşe Betül; Kılıçaslan, Cengizhan; Tuncer, Sibel Çiğdem (Düzce Üniversitesi, 2024)Aim: The diagnosis of appendicitis may be challenging in the pediatric population. It can be very difficult to examine a child or to take a medical history. The role of laboratory findings is still unclear. Therefore, we ... -
Serum zonulin levels are higher among children with autism spectrum disorders and correlated with social impairment
Kara, Halil; Açıkel, Sadettin Burak; Çetinkaya, Miray; Tuncer, Sibel Çiğdem (Cukurova University, 2021)Zonulin is a protein that affects the integrity of intercellular connections in the intestines. It has been emphasized that autoimmune diseases as well as neurodevelopmental disorders, for example autism spectrum disorder ... -
Sıçanlarda Sodyum Arsenit ile Oluşturulan Kalp Toksisitesi Üzerine Karvakrol’un Kardiyoprotektif Etkileri
Tuncer, Sibel Çiğdem; Kandemir, Özge; Gür, Cihan (Gümüşhane Üniversitesi, 2023)Sodyum arsenit, toksik bir bileşik olup milyonlarca insanın sağlığını etkilemektedir. Uzun süreli arsenit maruziyeti sonucunda kalp, böbrek ve karaciğer başta olmak üzere vücutta birçok doku etkilenmektedir. Karvakrol ... -
Sıçanlarda sodyum valproat kaynaklı mide hasarı üzerine rutin’in oksidatif stres, inflamasyon ve apoptoz üzerindeki koruyucu etkilerinin araştırılması
Tuncer, Sibel Çiğdem; Gür, Cihan; Akaras, Nurhan; Kandemir, Fatih Mehmet (Süleyman Demirel Üniversitesi, 2023)Sodyum valproat, antiepileptik ilaçlardan en yaygın kullanılanlardan birisi olup uzun süreli maruziyet so- nucunda toksik etkilidir. Uzun süreli sodyum valproat maruziyeti dokularda özellikle oksidatif stres ve infla- ... -
Tip 2 diyabetik hastalarda glisemik kontrolün D vitamini, B12 vitamini ve lipid profili üzerini etkilerinin araştırılması: bir retrospektif çalışma
Tekin Karacaer, Neslihan; Tuncer, Sibel Çiğdem (Aksaray Üniversitesi, 2022)Tip 2 diyabet hızla büyüyen bir halk sağlığı sorunudur. Türkiye'de tip 2 diyabet hastalarında oral antidiyabetik kullanımının D vitamini, B12 vitamini ve lipid profili üzerine etkisi hakkında sınırlı veri bulunmaktadır. ... -
The use of calprotectin and other inflammatory parameters in the investigation of pseudoexfoliation syndrome concomitant glaucoma and systemic diseases
Yaşar, Erdoğan; Erdal, Hüseyin; Tuncer, Sibel Çiğdem; Akbulut Yağcı, Betül (Wolters Kluwer, 2024)Purpose: The present study aimed to investigate the value of calprotectin and other inflammatory parameters in patients with glaucoma and systemic diseases accompanying pseudoexfoliation syndrome (PEX-S). Methods: This ...