Browsing by Author "Toksoy, Alihan"
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Bor içeren yakın kızılötesi görüntüleme ajanın sentezi ve özellikleri
Toksoy, Alihan (Aksaray Üniversitesi Fen Bilimleri Enstitüsü, 2021)Kanser, hücrelerin DNA molekülünde oluşan mutasyonların birikmesiyle, kontrolsüz veya anormal bölünmesi ve çoğalmasıdır. Kanserin tedavisi için birçok yöntem (ameliyat, kemoterapi, radyoterapi vb.) kullanılmaktadır. Bu ... -
A generic platform for self-illuminating unimolecular systems enabling photodynamic therapy
Toksoy, Alihan; Pekcan, Simge; Susam, Alim; Erkan, Dilek Sadife; Algı, Melek Pamuk; Algı, Fatih (Elsevier Ltd, 2023)This work delineates a generic platform, 1-((1,4-dioxo-1,2,3,4-tetrahydrophthalazin-6-yl)methyl)-1H-1,2,3-triazol-4-yl)methyl 2-(6-hydroxy-3-oxo-3H-xanthen-9-yl)benzoate, (conjugate 1), for self-illuminating unimolecular ... -
N-doped carbon nanomaterials as fluorescent pH and metal ion sensors for imaging
Sonkaya, Ömer; Ocakçı, Şeyma; Toksoy, Alihan; Pamuk Algı, Melek; Algı, Fatih (Elsevier B.V., 2023)Herein we describe the facile synthesis of new N-doped carbon nanoparticles (CNPs) obtained from 1,10-phenanthroline by the solvothermal method. Characterization of CNPs were carried out with transmission electron microscope ... -
Norsquaraine endowed with anticancer and antibacterial activities
Boran Gülen, Rukiye; Sonkaya, Ömer; Erkan, Dilek Sadife; Toksoy, Alihan; Algı, Melek Pamuk; Algı, Fatih (Elsevier B.V., 2022)Photodynamic therapy (PDT) is a method for the treatment of cancer. Furthermore, PDT can also be used for the eradication of bacteria. The photo-sensitizing drug, a.k.a photosensitizer, is critical for the success of PDT. ... -
Transdermal delivery system to release phthalocyanine photosensitizers for the potential treatment of skin cancer with PDT
Çamur Demir, Meryem; Kurşun Baysak, Fatma; Boyar, Caner Yahya; Toksoy, Alihan; Algı, Fatih (TUBITAK, 2024)This research aims to examine the transdermal release of water-soluble indium and zinc metallo phthalocyanine (InPc and ZnPc) compounds from the poly(vinyl alcohol) (PVA) membrane and the cytotoxicity effect of these Pcs ...