Aksaray Üniversitesi Kurumsal Akademik Arşivi
DSpace@Aksaray, Aksaray Üniversitesi tarafından doğrudan ve dolaylı olarak yayınlanan; kitap, makale, tez, bildiri, rapor, araştırma verisi gibi tüm akademik kaynakları uluslararası standartlarda dijital ortamda depolar, Üniversitenin akademik performansını izlemeye aracılık eder, kaynakları uzun süreli saklar ve telif haklarına uygun olarak Açık Erişime sunar.
Güncel Gönderiler
Fractional integral inequalities for s-convex functions in the first sense
(Taylor and Francis Ltd., 2025) Tınaztepe, Gültekin; Yeşilce Işık, İlknur
Certain fractional integral inequalities via general fractional integral operator are presented for s-convex functions in the first sense. Also, they are restated in terms of the Riemann-Liouville and Hadamard fractional integrals and illustrated.
C-reactive protein-to-albumin ratio and systemic immune-inflammatory index as potential markers in distinguishing acute cerebellar infarction from benign paroxysmal positional vertigo
(Riyadh Armed Forces Hospital, 2025) Şahin, Oruç; Güneş, Muzaffer; Dönmez, Recep
To investigate the potential utility of the C-reactive protein-to-albumin ratio (CAR) and the systemic immune-inflammatory index (SII) as a biomarker in distinguishing between BPPV and acute cerebellar infarction (ACI) due to posterior inferior cerebellar artery (PICA) involvement. METHODS: The data of 2545 patients registered in our hospital database between 2017 and 2024 with a diagnosis of vertigo were retrospectively analyzed and 102 patients with benign paroxysmal positional vertigo (BPPV) and 100 patients with ACI were included in the study. Mann-Whitney U test, Chi-square test, or Fisher's exact test were used to compare variables between the two groups. Receiver operating characteristic (ROC) curve analysis was performed to investigate the predictive value of the data. RESULTS: The CAR and SII values were significantly higher in the ACI group compared to the BPPV group (p<0.001, p<0.001, respectively). The areas under the ROC curve (AUC) were as follows: CAR=0.768 (95% CI, 0.705-0.832), white blood cell count (WBC)=0.735 (95% CI, 0.667-0.802), monocytes=0.622 (95% CI, 0.544-0.699), red cell distribution width-standard deviation (RDW-SD)=0.600 (95% CI, 0.522-0.678), SII=0.674 (95% CI, 0.599-0.748), and neutrophil-to-lymphocyte ratio (NLR)=0.687 (95% CI, 0.613-0.761). CONCLUSION: CAR and SII could be useful biomarkers to differentiate between ACI and BPPV in vertigo patients, but further validation is needed in larger studies.
Efficiency Assessment of Healthcare Resources: An In-Depth Exploration Using SFA, DEA, and Capacity Utilization Indicators
(John Wiley and Sons Inc, 2025) Yetim, Birol; İlgün, Gülnur; Konca, Murat; Şahin, Bayram
The demand for health care has increased. This demand causes an increase in the resources allocated and pressures on health managers and policymakers. Thus, it is important to evaluate the efficiency. It aimed to investigate the efficiency of the hospitals operating in Turkey. Stochastic Frontier Analysis (SFA), Data Envelopment Analysis (Charnes, Cooper and Rhodes Model [CCR] and Banker, Charnes and Cooper Model [BCC]), and capacity utilization indicators (bed occupancy ratio [BOR], bed turnover rate [BTR], and average length of stay [LoS]) were used. Thirty-nine of the 96 hospitals were found to be efficient according to BCC. It found that there was a strong correlation between the CCR model and SFA. It was moderate between BCC and SFA. Also, it was seen that there were significant differences between the SFA and BTR averages of the hospitals that were found to be efficient and inefficient. However, there were no significant differences between the averages of BOR and LoS. It is thought that the results obtained from different methods will help decision makers to better understand and monitor the performance of hospitals.
Effectiveness of Wharton's jelly mesenchymal stem cell medium on burn wound healing: Focus on apoptosis, necrosis, and autophagy
(Universidad del Zulia, Facultad de Ciencias Veterinarias, 2025) Çelik Kenar, Zeynep; Tuzcu, Mehmet; Akçakavak, Gökhan; Majidov, Nijat; Öner, Muhammed; Tural Çifçi, Ayşenur; Şahin, Rabia
The aim of this study is to evaluate the treatment efficacy of Platelet–Rich Plasma (PRP), silver sulfadiazine, and Wharton Jelly Mesenchymal Stem Cell–Derived Conditioned Medium (WJ–MSC– CM) on burn wounds using a rat model. The study included four groups, each with 16 rats, and the groups were further divided into two subgroups (n=8) for the 7th and 14th days of the treatment process. Group 1 received no treatment after the burn. Group 2 received PRP (Platelet–Rich Plasma) treatment on the first day after the burn. Group 3 was treated with silver sulfadiazine on the first day after the burn. Group 4 received WJ–MSC–CM on the first day after the burn. In the current study, the expression of Caspase–3, Bcl–2, TNF–α, p21, and Beclin–1 genes among the groups was evaluated by Real–time PCR. The silver sulfadiazine and WJ–MSC–CM treatment groups exhibited lower Bcl–2 expression and higher Caspase–3 and Beclin–1 expression compared to the other groups. TNF–α and p21 expression was high in the burn control group and showed lower expression in the treated groups. The current findings demonstrate that WJ–MSC–CM exhibits healing efficacy on burn wounds comparable to the reference drug (silver sulfadiazine) by inducing apoptosis and autophagy and reducing necroptosis and DNA damage. Additionally, PRP provided some positive benefits compared to the control group but was less effective than the other treatments.
Enhancing Beef Meat Emulsion: The Role of Banana Peel Albedo Powder
(Polish Academy Sciences. Institute of Animal Reproduction and Food Research, 2025) Ünal, Kübra; Dilek, Nazik M.; Alp, Halime; Erdem, Nuran; Babaoğlu, Ali S.
This study aimed to evaluate the effects of banana peel albedo powder (BPAP) on the physicochemical and microstructural properties of beef meat emulsions. The emulsions were formulated with BPAP added at levels of 0% (control), 0.5%, 1.0%, and 1.5% of the weight of the raw beef used. Due to the formulation process, the final BPAP contents in the emulsions were 0%, 0.013%, 0.025%, and 0.038% (w/v), respectively. BPAP, 100 g, was found to contain 25.19 g insoluble and 6.20 g soluble dietary fiber. Among the minerals analyzed, calcium and zinc showed the highest content in BPAP. Incorporation of BPAP at a level of 1.5% of raw beef (w/w) to the emulsion resulted in the higher water holding capacity and the lowest cooking loss compared to control. Furthermore, the addition of BPAP up to a 1.0% of raw beef (w/w) level enhanced the emulsion capacity, emulsion stability, and apparent viscosity of the samples. Confocal laser scanning microscopy micrographs revealed that the emulsions containing BPAP at 0.5% and 1% of raw beef (w/w) exhibited a more stable and homogeneous microstructure. These findings suggest that BPAP, particularly at 1.0% of raw beef (w/w) level (0.025% in emulsion, w/v), can be effectively utilized as a natural functional ingredient to improve the quality of meat emulsions in food formulations.
