Browsing by Author "Odabaşı, Mehmet"
Now showing items 1-20 of 71
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Alpha-Amylase immobilized composite cryogels: some studies on kinetic and adsorption factors
Acet, Ömür; İnanan, Tülden; Acet, Burcu Önal; Dikici, Emrah; Odabaşı, Mehmet (Springer, 2021)Stability of enzymes is a significant factor for their industrial feasibility. alpha-Amylase is an important enzyme for some industries, i.e., textile, food, paper, and pharmaceutics. Pumice particles (PPa) are non-toxic, ... -
Anti-cancer activity of naringenin loaded smart polymeric nanoparticles in breast cancer
Yıldırım, Metin; Acet, Ömür; Yetkin, Derya; Acet, Burcu Önal; Karakoç, Veyis; Odabaşı, Mehmet (Editions de Sante, 2022)Breast cancer is the most common form of cancer among women worldwide, and approximately comprise 25% of all female malignancies. Naringenin (Nar) is a promising anticancer agent for breast cancer. However, its use as a ... -
Application of cu2+-attached magnetite nanoparticles embedded supermacroporous monolithic composite cryogels for DNA adsorption
Ceylan, Şeyda; Kalburcu, Tülden; Gedikli, Mehmet; Odabaşı, Mehmet (Hacettepe Üniversitesi, 2011)Kriyojeller ayırma biliminde yeni nesil sabit faz olarak değerlendirilmektedirler. Kriyojeller, altakım işlemlerinde protein, enzim, DNA, hücre organelleri ve virüsler gibi biyomoleküllerin ayrılması ve saflaştırılmasında ... -
Assessment of a new dual effective combo polymer structure for separation of lysozyme from hen egg white
Acet, Ömür; Menteş, Ayfer; Odabaşı, Mehmet (Springer, 2020)Water-soluble O-carboxymethyl chitosan (O-CMCS) Schiff base granules were prepared, and Cu2+ ions were decorated. Then, dual effective combo cryogel structures were prepared by free radical polymerization using Cu2+-O-CMCS ... -
Bakteriyel kökenli ekstraselüler biyopolimerlerin protein adsorpsiyon davranışlarının incelenmesi için imak uygulamaları
Bani, Nurullah (Aksaray Üniversitesi Fen Bilimleri Enstitüsü, 2018)Bu çalışmada, endüstriyel açıdan son derece önemli bir enzim olan α-amilazın efektif bir yöntemle ortamdan saflaştırılması için afinite kromatografisi metotlarından popüler bir yöntem olan immobilize metal afinite ... -
Biopolymeric Composite Columns for Improving Water Quality in a Freshwater Stream Receiving Wastewater Treatment Plant Effluents
Akpınar, Şahin; Gürbüz, Fatma; Özcan, Samet; Odabaşı, Mehmet (Springer, 2024)Inefficiently treated wastewater, which contains a high concentration of pollutants, is hazardous when it is mixed with the clean water of rivers and lakes. Nitrate in particular is a major global problem that leads to ... -
Cholesterol imprinted composite membranes for selective cholesterol recognition from intestinal mimicking solution
Odabaşı, Mehmet; Uzun, Lokman; Baydemir, Gözde; Aksoy, Neşe Hayat; Acet, Ömür; Erdönmez, Demet (Elsevier, 2018)Molecularly imprinted polymers which have been extensively investigated as selective adsorbents were constructed using a template molecule during the polymerization to gain template-specific cavities. In this study, we ... -
Co-evaluation of interaction parameters of genomic and plasmid DNA for a new chromatographic medium
Önal, Burcu; Acet, Ömür; Sanz, Raúl; Sanz-Pérez, Eloy S.; Erdönmez, Demet; Odabaşı, Mehmet (Elsevier B.V., 2019)Preparation of new sorbents specific to DNA has a great significance in many biomedical fields. This study reports a new sorbent with high surface area and porosity to immobilize nucleic acids having both high molecular ... -
Comparative study of ASNase immobilization on tannic acid-modified magnetic Fe3O4/SBA-15 nanoparticles to enhance stability and reusability
Noma, Samir Abbas Ali; Ulu, Ahmet; Acet, Ömür; Sanz, Raúl; Sanz-Pérez, Eloy S.; Odabaşı, Mehmet; Ateş, Burhan (Royal Society of Chemistry, 2020)In this work, l-asparaginase was immobilized on tannic acid-modified magnetic mesoporous particles. In brief, Fe3O4/SBA-15/tannic acid magnetic particles were synthesized, and their structures and morphologies were fully ... -
The creation of selective imprinted cavities on quartz crystal microbalance electrode for the detection of melamine in milk sample
Cömert, Şeyda Ceylan; Özgür, Erdoğan; Uzun, Lokman; Odabaşı, Mehmet (Elsevier, 2022)Molecularly imprinted polymer based nanofilms specific to melamine were synthesized on quartz crystal microbalance (QCM) electrode surface. Contact angle measurements, atomic force microscopy, ellipsometry and scanning ... -
Cu2+ takılı O-karboksimetil kitosan Schiff bazı kompleksleri gömülü kompozit membranların hazırlanması ve protein adsorpsiyon davranışlarının incelenmesi
Acet, Ömür (Aksaray Üniversitesi Fen Bilimleri Enstitüsü, 2015)Bu çalışma kapsamında, lizozimin etkin bir şekilde ayrılması için afinite kromatografisi yöntemleri arasında, son yıllarda yoğun bir uygulama alanı bulan, İmmobilize Metal Afinite Kromatografisi (İMAK) kullanılmıştır. Bu ... -
Cu2+-attached pumice particles embedded composite cryogels for protein purification
Alkan, Hüseyin; Cömert, Şeyda Ceylan; Gürbüz, Fatma; Doğru, Mehmet İlker; Odabaşı, Mehmet (Taylor & Francis Group, 2017)In this study, chromatographic performance of Cu2+-attached pumice particles embedded to monolithic cryogels (Cu2+-APPsEMC) for human serum albumin (HSA) was investigated. Monolithic composite cryogels were prepared by ... -
Design and application of a newly generated bio/synthetic cryogel column for DNA capturing
Önal, Burcu; Odabaşı, Mehmet (Springer Science and Business Media Deutschland GmbH, 2020)The need for high amounts of plasmid (p) and genomic (g) DNA separation is increasing day by day for gene therapy, DNA vaccination, etc. Here, extracellular polymeric substances (EPS) used as a binding agent for Fe3+ ions, ... -
Detection of N-hexanoyl-L-homoserine lactone via MIP-based QCM sensor: preparation and characterization
Acet, Ömür; Odabaşı, Mehmet (Springer Science and Business Media Deutschland GmbH, 2023)While high living organisms use sounds and words to communicate with each other, bacteria provide this function with some communication molecules. These communication molecules are expressed as “Quorum Sensing” (QS) or ... -
Determination of some adsorption and kinetic parameters of alpha-amylase onto Cu+2-PHEMA beads embedded column
Acet, Ömür; Aksoy, Neşe Hayat; Erdönmez, Demet; Odabaşı, Mehmet (Taylor & Francis Ltd, 2018)In order to investigate the biocatalytic properties of alpha-amylase on a composite cryogel matrix with immobilized metal affinity chromatography, Cu+2-attached poly(2-hydroxyethyl methacrylate) (Cu+2-PHEMA) beads, (2 mu ... -
Differences between Cu- and Fe–Cu nanoflowers in their interactions with fluorescent probes ANS and Fura-2 and proteins albumin and thrombin
Halets‑BuiIn, Inessa; Dzmitruk, Volha; Abashkin, Viktar; Loznikova, Svetlana; Acet, Ömür; Önal, Burcu; Özdemir, Nalan; Bryszewska, Maria; Odabaşı, Mehmet; Shcharbin, Dzmitry (Springer Science and Business Media Deutschland GmbH, 2022)Among nanomaterials, we can now distinguish a special class called nanoflowers (NFs). These new nanostructures have aroused the interest of scientists due to the topographic features of nanolayers, the special location ... -
Dipeptide nanostructures: Synthesis, interactions, advantages and biomedical applications
Ömür, Acet; Shcharbin, Dzmitry; Zhogla, Victoriya; Kirsanov, Pavel; Halets-Bui, Inessa; Önal Acet, Burcu; Gök, Tuba; Bryszewska, Maria; Odabaşı, Mehmet (Elsevier, 2023)Short peptides are important in the design of self-assembled materials due to their versatility and flexibility. Self-assembled dipeptides, a group of peptide nanostructures, have highly attractive uses in the field of ... -
DNA saflaştırılmasına yönelik bakteriyel kökenli ekstraselüler biyopolimer kompozit kriyojellerin İMAK uygulamaları
Önal, Burcu (Aksaray Üniversitesi Fen Bilimleri Enstitüsü, 2018)Bu çalışmada, DNA'nın etkili bir yolla ayrılması için kullanılan afinite kromatografisi metotları arasında olan ve son zamanlarda yoğun bir uygulama sahası bulan, immobilize metal afinite kromatografisinden (İMAK) ... -
Efficient adsorption of hemoglobin from aqueous solutions by hybrid monolithic cryogel column
Yılmaz Baran, Nuray; Acet, Ömür; Odabaşı, Mehmet (Elsevier Science Bv, 2017)In this study, a supermacroporous poly(2-hydroxyethyl methacrylate) (PHEMA)-based Cu2+-attached bentonite particles embedded hybrid monolithic cryogel (Cu2+-ABPs EHMC) was prepared by radical cryo-copolymerization of HEMA ... -
Fe3+ takılı nanoflower'ların sentezi ve DNA'ya karşı özgüllüğünün araştırılması
Serinbaş, Ayça (Aksaray Üniversitesi Fen Bilimleri Enstitüsü, 2020)Saflaştırma yönteminin ve adsorban tipinin seçimi, deoksiribonükleik asit (DNA) gibi bir biyomolekülün saflaştırılması için yüksek öneme sahiptir. Nanoflower'lar yeni geliştirilmiş bir adsorban sınıfıdır. Bitki çiçeklerine ...
