Browsing by Author "Aygörmez, Serpil"
Now showing items 1-5 of 5
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Anti-oxidant, Anti-inflammatory, and Anti-apoptotic Effects of Rutin in Spleen Toxicity Induced by Sodium Valproate in Rats
Akaras, Nurhan; Kandemir, Fatih Mehmet; Şimşek, Hasan; Gür, Cihan; Aygörmez, Serpil (Bingöl Üniversitesi Fen Bilimleri Enstitüsü, 2023)Long-term exposure to sodium valproate, an anti-epileptic drug, causes toxic effects in tissues, especially by increasing oxidative stress and inflammation. Rutin is a flavanoid with anti- oxidant, anti-inflammatory and ... -
Effects of chrysin in cadmium-induced testicular toxicity in the rat; role of multi-pathway regulation
Tuncer, Sibel Çiğdem; Küçükler, Sefa; Gür, Cihan; Aygörmez, Serpil; Kandemir, Fatih Mehmet (Springer Science and Business Media B.V., 2023)Cadmium (Cd) is a strong toxic agent and causes serious damage to testicular tissues. Chrysin (CHR) is a natural flavonoid with many effective properties, especially antioxidant, anti-inflammatory and anti-apoptotic ... -
Naringin protects against colistin-induced sciatic nerve damage by reducing oxidative stress, apoptosis and inflammation damage
Yılmaz, Selçuk; Küçükler, Sefa; Şi̇mşek, Hasan; Aygörmez, Serpil; Kandemir, Fatih Mehmet (Ondokuz Mayis Universitesi, 2024)Colistin is used in treatment against gram-negative bacteria. It causes toxic effects due to oxidative stress in a dose-dependent manner. Naringin is a flavonoid with strong antioxidant properties found naturally in many ... -
Protective effects of zingerone against sodium arsenite-induced lung toxicity: A multi-biomarker approach
Şimşek, Hasan; Küçükler, Sefa; Gür, Cihan; İleritürk, Mustafa; Aygörmez, Serpil; Kandemir, Fatih Mehmet (Mashhad University of Medical Sciences, 2023)Sodium arsenite (SA) exposure is toxic to the body. Zingerone (ZNG) is a flavonoid with many biological properties found naturally in honey and plants. This study aimed to determine the effects of ZNG on SA-induced rat ... -
Sıçanlarda İfosfamid ile Oluşturulmuş Mide Hasarında Morinin Etkilerinin Histopatolojik ve Biyokimyasal Olarak İncelenmesi
Akaras, Nurhan; İleritürk, Mustafa; Kandemir, Fatih Mehmet; Şimşek, Hasan; Aygörmez, Serpil (Mustafa İSSİ, 2023)Bu çalışmada, sıçanlarda deneysel ifosfamid (IFO) uygulamasının neden olduğu mide toksisitesi üzerine morinin (MOR) etkilerinin belirlenmesi amaçlandı. Bu amaçla deney hayvanları beş gruba (n=7) ayrıldı. Gruplar kontrol, ...