Browsing by Author "İleritürk, Mustafa"
Now showing items 1-18 of 18
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Ameliorative effects of sinapic acid against vancomycin-induced testicular oxidative damage, apoptosis, inflammation, testicular histopathologic disorders and decreased epididymal sperm quality
Akarsu, Serkan Ali; İleritürk, Mustafa; Küçükler, Sefa; Akaras, Nurhan; Gür, Cihan; Kandemir, Fatih Mehmet (Elsevier, 2024)In this study, it was aimed to determine the effect of sinapic acid (SNP), a polyphenol with antioxidant, anti-inflammatory and antibacterial properties, on testicular damage caused by vancomycin (VCM), a widely used ... -
Carvacrol Ameliorates Sodium Arsenite-Induced Intestinal Toxicity
İleritürk, Mustafa; Kandemir, Özge (Bingöl Üniversitesi Fen Bilimleri Enstitüsü, 2023)Arsenic is a very dangerous metal that is widely distributed in the environment as a result of anthropogenic and natural processes. On the other hand, it is thought that treatment with natural flavonoids may protect against ... -
Carvacrol protects against λ-Cyhalothrin-induced hepatotoxicity and nephrotoxicity by modulating oxidative stress, inflammation, apoptosis, endoplasmic reticulum stress, and autophagy
İleritürk, Mustafa; Kandemir, Fatih Mehmet (John Wiley and Sons Inc, 2023)λ-Cyhalothrin, a type II synthetic pyrethroid, has been widely used in households, agriculture, public health, and gardening to control insect pests. Despite its widespread usage, it is known to induce a variety of adverse ... -
Carvacrol Reduces Mercuric Chloride-Induced Testicular Toxicity by Regulating Oxidative Stress, Inflammation, Apoptosis, Autophagy, and Histopathological Changes
Şimşek, Hasan; Gür, Cihan; Küçükler, Sefa; İleritürk, Mustafa; Akaras, Nurhan; Öz, Mehmet; Kandemir, Fatih Mehmet (Springer, 2023)Mercuric chloride (HgCl2) is a heavy metal that is toxic to the human body. Carvacrol (CAR) is a flavonoid found naturally in plants and has many biological and pharmacological activities including anti-inflammatory, ... -
Effect of syringic acid on oxidative stress, autophagy, apoptosis, inflammation pathways against testicular damage induced by lead acetate.
Akarsu, Serkan Ali; Gür, Cihan; İleritürk, Mustafa; Akaras, Nurhan; Küçükler, Sefa; Kandemir, Fatih Mehmet (Elsevier GmbH, 2023)Heavy metals are one of the environmental pollutants. Lead (Pb) is one of the most common of these heavy metals. In this study, it was aimed at investigating the effects of syringic acid (SA) against testicular toxicity ... -
Evaluation of protective effects of quercetin against cypermethrin-induced lung toxicity in rats via oxidative stress, inflammation, apoptosis, autophagy, and endoplasmic reticulum stress pathway
İleritürk, Mustafa; Kandemir, Özge; Kandemir, Fatih Mehmet (John Wiley and Sons Inc, 2022)Cypermethrin (CYP), a type II synthetic pyrethroid, is the most widely used insecticide worldwide. Inhalation of it may cause side effects. This study is aimed to examine potential protection of quercetin (QUE) which is a ... -
Hesperidin has a protective effect on paclitaxel-induced testicular toxicity through regulating oxidative stress, apoptosis, inflammation and endoplasmic reticulum stress
İleritürk, Mustafa; Kandemir, Özge; Akaras, Nurhan; Şimsek, Hasan; Genç, Aydın; Kandemir, Fatih Mehmet (Elsevier Inc., 2023)Paclitaxel (PTX) is widely used to treat a number of malignancies, although it has toxic side effects. Hesperidin (HES) has a wide range of biological and pharmacological properties, including anti-inflammatory and antioxidant ... -
Morin provides therapeutic effect by attenuating oxidative stress, inflammation, endoplasmic reticulum stress, autophagy, apoptosis, and oxidative DNA damage in testicular toxicity caused by ifosfamide in rats
Çakmak, Fatma; Küçükler, Sefa; Gür, Cihan; Çomaklı, Selim; İleritürk, Mustafa; Kandemir, Fatih Mehmet (Mashhad : Mashhad University of Medical Sciences, 2023)Objectives: In the present study, it was evaluated whether morin has a protective effect on testicular toxicity caused by ifosfamide (IFOS), which is used in the treatment of various malignancies. Materials and methods: ... -
Naringin attenuates oxaliplatin-induced nephrotoxicity and hepatotoxicity: A molecular, biochemical, and histopathological approach in a rat model
İleritürk, Mustafa; Kandemir, Özge; İleritürk, Duygu; Akaras, Nurhan; Şimşek, Hasan; Erdoğan, Ender; Kandemir, Fatih M. (Wiley, 2024)Oxaliplatin (OXL) is a significant therapy agent for the worldwide increase in cancer cases. Naringin (4′,5,7‐trihydroxy flavonon 7‐rhamnoglucoside, NRG) has a wide range of biological and pharmacological activities, ... -
Naringin protects against paclitaxel-induced toxicity in rat testicular tissues by regulating genes in pro-inflammatory cytokines, oxidative stress, apoptosis, and JNK/MAPK signaling pathways
Kankılıç, Nazım Abdülkadir; Küçükler, Sefa; Gür, Cihan; Akarsu, Serkan Ali; Akaras, Nurhan; Şimşek, Hasan; İleritürk, Mustafa; Kandemir, Fatih Mehmet (John Wiley and Sons Inc, 2024)Paclitaxel (PTX), which is actively used in the treatment of many types of cancer, has a toxic effect by causing increased oxidative stress in testicular tissues. Naringin (NRG) is a natural flavonoid found in plants, and ... -
Protective Effect of Morin Hydrate in Ischemia/Reperfusion Injury of Rat Skeletal Muscle
Semis, Halil Sezgin; İleritürk, Mustafa; Gür, Cihan; Kaynar, Özgür; Kandemir, Fatih Mehmet (Veteriner Hekimler Derneği, 2023)Reaktif oksijen türlerinin neden olduğu hücre hasarı iskemi/reperfüzyon (I/R) hasarında temel etiyolojik faktör olarak kabul edilmektedir. Bu nedenle sunulan çalışmada morin’in iskelet kası I/R hasarındaki etkilerinin ... -
Protective Effect of Rutin on Malathion-induced Gastric Toxicity: Evaluation of Oxidative Stress, Inflammation and Apoptosis
İleritürk, Mustafa; Kandemir, Özge (Mesut AKSAKAL, 2023)Malathion (MLT) is widely used as an insecticide in agricultural, veterinary, medicinal, and public health applications. MLT is taken up by the body through the skin, respiratory, and gastrointestinal systems. Rutin (RUT) ... -
The protective effects of chrysin on cadmium-induced pulmonary toxicity; a multi-biomarker approach
Akaras, Nurhan; İleritürk, Mustafa; Gür, Cihan; Küçükler, Sefa; Öz, Mehmet; Kandemir, Fatih Mehmet (Springer Science and Business Media Deutschland GmbH, 2023)This study aimed to determine the potential protective effects of chrysin (CHR) on experimental cadmium (Cd)-induced lung toxicity in rats. To this end, rats were divided into five groups; Control, CHR, Cd, Cd + CHR25, Cd ... -
Protective effects of naringin on colistin-induced damage in rat testicular tissue: Modulating the levels of Nrf-2/HO-1, AKT-2/FOXO1A, Bax/Bcl2/Caspase-3, and Beclin-1/LC3A/LC3B signaling pathways
Kankılıç, Nazım Abdülkadir; Şimşek, Hasan; Akaras, Nurhan; Gür, Cihan; İleritürk, Mustafa; Küçükler, Sefa; Akarsu, Serkan A.; Kandemir, Fatih M. (John Wiley and Sons Inc, 2024)Antimicrobial agent resistance has become a growing health issue across the world. Colistin (COL) is one of the drugs used in the treatment of multidrug-resistant bacteria resulting in toxic effects. Naringin (NRG), a ... -
Protective effects of syringic acid against oxidative damage, apoptosis, autophagy, inflammation, testicular histopathologic disorders, and impaired sperm quality in the testicular tissue of rats induced by mercuric chloride
Akarsu, Serkan Ali; Gür, Cihan; Küçükler, Sefa; Akaras, Nurhan; İleritürk, Mustafa; Kandemir, Fatih Mehmet (John Wiley and Sons Inc, 2024)Mercury (Hg) is one of the most toxic heavy metals that damage testicular tissue. Mercury chloride (HgCl2) is one of the most toxic forms of mercury that can easily cross biological membranes. Syringic acid (SA) is a natural ... -
Protective effects of zingerone against sodium arsenite-induced lung toxicity: A multi-biomarker approach
Şimşek, Hasan; Küçükler, Sefa; Gür, Cihan; İleritürk, Mustafa; Aygörmez, Serpil; Kandemir, Fatih Mehmet (Mashhad University of Medical Sciences, 2023)Sodium arsenite (SA) exposure is toxic to the body. Zingerone (ZNG) is a flavonoid with many biological properties found naturally in honey and plants. This study aimed to determine the effects of ZNG on SA-induced rat ... -
Sinapic acid protects against lead acetate-induced lung toxicity by reducing oxidative stress, apoptosis, inflammation, and endoplasmic reticulum stress damage
Akaras, Nurhan; Küçükler, Sefa; Gür, Cihan; İleritürk, Mustafa; Kandemir, Fatih Mehmet (John Wiley and Sons Inc, 2024)Lead acetate (PbAc) is a compound that produces toxicity in many tissues after exposure. Sinapic acid (SNP) possesses many biological and pharmacological properties. This study aimed to investigate the efficacy of SNP on ... -
Sıçanlarda İfosfamid ile Oluşturulmuş Mide Hasarında Morinin Etkilerinin Histopatolojik ve Biyokimyasal Olarak İncelenmesi
Akaras, Nurhan; İleritürk, Mustafa; Kandemir, Fatih Mehmet; Şimşek, Hasan; Aygörmez, Serpil (Mustafa İSSİ, 2023)Bu çalışmada, sıçanlarda deneysel ifosfamid (IFO) uygulamasının neden olduğu mide toksisitesi üzerine morinin (MOR) etkilerinin belirlenmesi amaçlandı. Bu amaçla deney hayvanları beş gruba (n=7) ayrıldı. Gruplar kontrol, ...
