Antimicrobial and Antioxidant evaluation of fruit extract from Cornus mas L.
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Dosyalar
Tarih
2018
Yazarlar
Dergi Başlığı
Dergi ISSN
Cilt Başlığı
Yayıncı
Aksaray Üniversitesi
Erişim Hakkı
Attribution-NonCommercial-NoDerivs 3.0 United States
info:eu-repo/semantics/openAccess
info:eu-repo/semantics/openAccess
Özet
In this present study, water and methanol extracts of Cornelian cherry fruits (Cornus mas L.) were studied for evaluating of antioxidant and antimicrobial properties. The antioxidant properties were evaluated by determination of 2,2-Diphenyl-1-picrylhydrazyl (DPPH) radical scavenging ability and lipid peroxidation inhibition activity. Also total phenolic contents of the extracts were detected by Folin method. The extracts of the fruits have antioxidant potential. The DPPH radical scavenging activity was higher in water extract (36.6 %) than the methanol extract (30.6 %). Unlike, methanol extract of fruits have more activity (18.9 %) than water extract (16.7 %), also with higher phenolic compound contents. Antimicrobial activities of above extracts were also tested against 93 clinical isolates of human pathogenic strains belonging to 5 bacteria (Entorobacter aerogenes, Escherichia coli, Proteus mirabilis, Pseudomonas aeroginosa, Staphylococcus aureus) and 5 yeast species (Candida albicans, Candida glabrata, Candida krusei, Candida parapisilosis, Candida tropicalis) by diskdiffusion method. The results showed cornelian cherries are potentially rich source of antimicrobial agents. The most effective antibacterial activity was expressed by methanol and water extract of cornelian cherry fruit against S. aureus with 25 mm inhibition zone and 0.156 mg/ml Minimum Inhibitory Concentration (MIC) value. Only methanol extracts of the fruit have antifungal activity against tested human pathogen clinic isolates.
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Açıklama
Anahtar Kelimeler
Antimicrobial Activity, Antioxidant Activity, Cornelian Cherry
Kaynak
Aksaray University Journal of Science and Engineering
WoS Q Değeri
Scopus Q Değeri
Cilt
2
Sayı
1
