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Öğe Do Antiplatelet Drugs Use Contribute to Clinical Outcomes in Patients Receiving Penile Low- Intensity Shock Wave Therapy (Li-SWT) for Erectile Dysfunction?(Merthan TUNAY, 2023) Geyik, Serdar; Değer, Mutlu; Akdoğan, Nebil; Kankılıç, Nazım; Yılmaz, İsmail Önder; Arıdoğan, İbrahim AtillaLow-intensity extracorporeal shock wave therapy (Li-SWT) is one of the recommended treatment options in patients with erectile dysfunction (ED). Li-SWT is safe in patients using antiplatelet drugs (APs), however, there are no specific studies on the contribution of APs use to clinical improvement in erectile function. We aimed to evaluate the early clinical results of Li-SWT administration and whether the use of APs had an additional positive contribution to clinical improvement and safe in ED patients. Methods: Patients with ED for more than 6 months despite using (5 mg/day) PDE5i were included in our study. Patients treated with Li-SWT and using PDE5i were classified as Group 1, patients treated with Li-SWT and using APs and using PDE5i were considered Group 2. The evaluation results of the International Index of Erectile Function-Erectile Function Area(IIEF-EF) in all patients baseline and after treatment were examined. Results: There are 25 patients in each group. Analysis of IIEF-EF scores showed significant increases in both groups after treatment [group 1 (p=0.001); group 2 (p=0.001)]. When the IIEF-EF scores of the groups before and after the treatment were compared with each other; it was shown that baseline scores were similar(p=0.746) and that APs use had no statistically significant effect on post-treatment scores (p=0.613) No side effects were seen in APs. Conclusions: This study showed that penile Li-SWT significantly increases the IIEF-EF scores and response of (5 mg/day) PDE5i in ED patients and safe, also in AP users. However, Using AP in Li- SWT does not contribute positively to clinical results.Öğe Invited response on: autologous biological vitamin-C added (ABC) filler for facial volume restoration(Springer, 2022) Özer, Kadri; Atan, Oğuz; Çolak, ÖzlemDear Sir, We would like to thank Pensato et al. for their valuable comments regarding our recent article entitled ‘‘Autologous Biological Vitamin-C-added (ABC) Filler for Facial Volume Restoration’’ [1]. We are pleased that this study raised such an interest in the scientific community to discuss a new biological filler. The subjects mentioned in our study consisted of individuals over the age of 18 years who had no relevant diseases and were free of any medication known to affect platelet functions, including acetylsalicylic acid and any other nonsteroidal anti-inflammatory drugs, during for 7 days before the application. In our recent study, total blood count including platelet count, leukocytes concentration and the platelet/leukocyte ratio was not checked from each patient before ABC filler procedure.Öğe The use of higher proportions of platelet-rich plasma to enrich microfat has negative effects: A preclinical study(Lippincott Williams and Wilkins, 2020) Özer, Kadri; Atan, OğuzWe read the article by Abellan Lopez et al. that was published in January of 2020 concerning the effect of higher proportions of platelet-rich plasma to microfat graft with great interest.1 The authors should be applauded for selecting this topic; however, we are concerned about some statements that should be discussed.Öğe Demographic and clinical characteristics of atrial fibrillation patients suffering from an ACS without prior revascularization history(Oxford University Press, 2019) Coner, A.; Saraçoğlu, E.; Akdeniz, A.; Özkan, H.; Tülüce, K.; Gül, Murat; Coşkun, F. Y.; Kurt, D.; Karagöz, A.Background: The incidence of atrial fibrillation in acute coronary syndromes (ACS) ranges from 3% to 25%. The purpose of the current study was to investigate the demographic and baseline clinical characteristics, cardiovascular risk factors and comorbid conditions between patients (pts) with concomitant atrial fibrillation (AF) to those without AF in patients suffering from ACS without previous coronary artery bypass graft (CABG) and/or percutaneous coronary intervention.Öğe All pilonidal sinus surgery specimens should be histopathologically evaluated in order to rule out malignancy(Elsevier Ltd., 2019) Yüksel, Mehmet Eren; Tamer, Funda...Öğe Treatment of pilonidal disease with crystallized phenol has excellent cosmetic results with 80% success rate, but is it safe in pediatric patients?(W.B. Saunders, 2019) Yüksel, Mehmet ErenDear Editor, We have read the article “The Management of Pilonidal Disease: a Systematic Review” with great interest. Grabowski et al. made a valuable contribution to the field by summing up 97 articles related to the treatment of pilonidal disease [1]. Moreover, they commented on phenol as an effective method in the management of pilonidal disease with low recurrence and complication rates with level 2–4 evidence, grade B recommendation. Grabowski et al. also suggested further studies to evaluate the applicability of phenol in the pediatric populationÖğe An update on the drug safety of treating erectile dysfunction(Taylor & Francis, 2019) Gül, Murat; Şerefoğlu, Ege CanIntroduction: Treatment options for erectile dysfunction (ED) have evolved over the last two decades, particularly after the introduction of phosphodiesterase type-5 inhibitors (PDE5Is). The path, however, has not been straightforward with issues raised regarding safety and toxicity following ED treatments. Areas covered: A literature review was conducted on current evidence related to the safety of PDE5Is, intracavernosal injections and various older forms of oral therapies. Relevant trials were identified through a literature search of PubMed from 1980 to 2019. Expert opinion: PDE5Is are now recommended as the first line therapy for the treatment of ED due to their efficacy and tolerable side effects. Comparison of the various PDE5Is on safety has not been supported by prime evidence, and consequently, the negative aspects of each inhibitor appear the same as defined in the literature. Other means of therapies for ED are still in the running, and these also present a different range of side effects. While intracavernosal injections have potential to cause priapism and penile fibrosis, intraurethral alprostadil may result in more systematic side effects. Alternative topical ED therapies are generally limited with their local side effectsÖğe Generalised lichenoid drug eruption accompanied by hand-foot syndrome due to capecitabine(Medknow Publications & Media Pvt Ltd, 2018) Tamer, Funda; Yüksel, Mehmet Eren[Abstract Not Available]Öğe Management of staghorn renal stones(Taylor & Francis, 2018) Diri, Akif; Diri, BanuStaghorn stones are large branching stones that fill part of all of the renal pelvis and renal calyces and they can be complete or partial depending on the level of occupancy of the collecting system. Although kidney stones are commoner in men, staghorn stones are less often reported in men compared to women and they are usually unilateral. Due to the significant morbidity and potential mortality attributed to staghorn stones, prompt assessment and treatment is mandatory. Conversely, conservative treatment has been shown to carry a mortality rate of 28% in 10-year period and 36% risk of developing significant renal impairment. Staghorn stones are, therefore, significant disease entity that should be managed aggressively and effectively. Generally, the gold standard treatment for staghorn stones is surgical with a view to achieve stone-free collecting system and preserve renal function. Percutaneous nephrolithotomy should be the recommended first-line treatment for staghorn stones. Other non-surgical options are usually considered in combination with surgery or as monotherapy only if patients are surgically unfit. The decision for optimal treatment of staghorn stones should be individualized according to the circumstances of the patient involved and in order to do so, a closer look at the advantages and disadvantages of each option is necessary.Öğe Danger in unlabeled bottles: Analysis of corrosive substances(Turkish Society of Gastroenterology, 2015) Boybeyi, Özlem; Göllü, Gülnür; Kısa, Üçler; Bahadır, Berktuğ; Günal, Yasemin Dere; Küçük, Gönül; Aslan, Mustafa Kemal; Soyer, Tutku; Çakmak, Aytül Murat[No abstract available]
