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    Predictive factors for muscle weakness in Rheumatoid arthritis
    (Türkiye Fiziksel ve Rehabilitasyon Uzman Hekimleri Derneği, 2022) Önder, Mustafa Erkut; Kılıçarslan, Ayşegül; Keskin, Esra Dilek; Bodur, Hatice
    We aimed to determine muscle strength in patients with rheumatoid arthritis (RA) and several factors including structural joint damage that may affect decrease in muscle strength. The relations between muscle strength and quality of life and functional disability were examined. Material and Methods: Seventy five RA patients and 51 controls were involved. Demographic characteristics, body mass index, waist circumference, 25-hydroxy vitamin D, and patient global assessments of disease activity (PGA) were documented. Disease Activity Score-28 (DAS28), Visual Analog Scale-Pain (VAS-pain), Health Assessment Questionnaire (HAQ) and the Rheumatoid Arthritis Quality of Life Questionnaire (RAQoL) were calculated. Radiographs of the hands were evaluated by van der Heijde modified Sharp score (vdHSS). Grip strength of both hands was measured by Jamar dynamometer. Results: Demographics (age, gender) were not different between RA patients and control group. Grip strength of patients with RA (22.79±18.58) was lower than control group (26.00±11.25, p=0.04). There was a significant correlation with grip strength and disease duration, tender joint count, VAS-pain, PGA, DAS28, HAQ, RAQoL, erosion and narrowing score (p<0.05). DAS28 and erosion score were associated with grip strength in multivariate analyses p<0.05). Conclusion: This study showed that RA obtains decreased muscle strength, impaired function and quality of life. Joint space narrowing and disease activity are the main parameters that affect muscle strength.