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    Diagnostic role of serum testican and ubiquitin levels in patients with head trauma
    (Pharmamed Mado Ltd, 2024) Yazıcı, Ramiz; Basa Kalafat, Ayşe Fethiye; Mutlu, Hüseyin; Sarı, Eyüp; Kalafat, Utku Murat; Atik, Dilek; Cander, Başar
    We aimed to determine if testican-1 and ubiquitin can serve as early indicators for diagnosing worsening clinical course (presence of intraparenchymal pathology) and mortality in patients with moderate traumatic brain injury (TBI).In this study, we conducted an observational and prospective study in the Emergency Department (ED) of a tertiary care hospital. The department admitted an average of 25,000 patients per month between October 2020 and March 2021. We focused on patients over 18 years old with moderate traumatic brain injury (Glasgow coma score (GCS): 9–13). We compared the prognostic values of blood testican and ubiquitin levels with Receiver Operating Characteristic (ROC) analysis for intracranial pathologies resulting from head trauma. Additionally, we used logistic regression analysis to compare the effectiveness of these markers in diagnosing intraparenchymal injury. The study included a total of 89 patients, with 45 in the case group (moderate TBI) and 44 in the healthy control group. It was found that levels of ubiquitin and testican levels were significantly higher in patients with intraparenchymal pathology (p = 0.048, p = 0.046, respectively). The cut-off point for detecting intraparenchymal pathology was 161.3 pg/mL for testican (Area under curve (AUC): 0.810; min: 0.654; max: 0.965, p = 0.002) and 44.42 ng/mL for Ubiquitin (AUC: 0.863; min: 0.727; max: 1.000, p < 0.001). High testican-1 and ubiquitin levels were independent markers for intraparenchymal pathology in moderate head trauma.
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    Effects of workload and distance traveled on psychological resilience and values among emergency healthcare workers
    (TUBITAK, 2025) Yazıcı, Ramiz; Bala, Efe Demir; Basa Kalafat, Ayşe Fethiye; Sarı, Eyüp; Mutlu, Hüseyin; Güner, Hakan; Kaya, Hilmi; Tapkan, Rabia Birsen; Kalafat, Utku Murat; Doğan, Serkan
    Emergency medical services (EMS) personnel face significant challenges in their daily work, which can lead to burnout and affect their mental well-being. This study aimed to investigate how workload and distance traveled, as specific aspects of EMS work, influence the psychological resilience and values of EMS personnel. The Connor–Davidson Resilience Scale (CD-RISC) and Spiritual and Humanistic Value Scale (SHVS) were utilized to assess psychological resilience and values, respectively. Materials and methods: A cross-sectional study was conducted among EMS personnel in Ankara, Türkiye, utilizing a questionnaire survey distributed between 23 and 30 May 2024. The study was approved by the Medical Research Scientific and Ethical Evaluation Board of Ankara Bilkent City Hospital. A total of 293 EMS personnel participated after providing informed consent and approval. The participants were categorized into 3 groups based on their case/distance ratio. We used the CD-RISC and SHVS to compare psychological resilience and values between the groups. Results: Significant differences were observed according to various sociodemographic and work-related variables among the participating EMS personnel. Younger personnel tended to handle more cases, while older personnel traveled longer distances on average (p < 0.001). Education level and experience also influenced workload allocation, with less experienced individuals and those with lower education levels handling more cases (p < 0.001). No significant differences were found in CD-RISC and SHVS scores between the considered groups; however, we identified significant differences based on sex (p = 0.005) for the CD-RISC and based on age (p < 0.05) and experience (p < 0.05) for the SHVS. Conclusion: This study highlights the complex relationship among workload, sociodemographic factors, and psychological resilience/ values in EMS personnel. Older, more experienced personnel tended to exhibit higher resilience and values scores, suggesting greater adaptation and satisfaction. Understanding these dynamics can aid in developing targeted interventions to prevent burnout and promote the well-being of EMS personnel.