Yazar "Horasan, Murat" seçeneğine göre listele

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    Computationally derived endosteal strain and strain gradients correlate with increased bone formation in an axially loaded murine tibia model
    (Elsevier Ltd, 2024) Horasan, Murat; Verner, Kari A.; Yang, Haisheng; Main, Russell P.; Nauman, Eric A.
    Osteoporosis is a common metabolic bone disorder characterized by low bone mass and microstructural degradation of bone tissue due to a derailed bone remodeling process. A deeper understanding of the mechanobiological phenomena that modulate the bone remodeling response to mechanical loading in a healthy bone is crucial to develop treatments. Rodent models have provided invaluable insight into the mechanobiological mechanisms regulating bone adaptation in response to dynamic mechanic stimuli. This study sheds light on these aspects by means of assessing the mechanical environment of the cortical and cancellous tissue to in vivo dynamic compressive loading within the mouse tibia using microCT-based finite element model in combination with diaphyseal strain gauge measures. Additionally, this work describes the relation between the mid-diaphyseal strains and strain gradients from the finite element analysis and bone formation measures from time-lapse in vivo tibial loading with a fluorochrome-derived histomorphometry analysis. The mouse tibial loading model demonstrated that cancellous strains were lower than those in the midshaft cortical bone. Sensitivity analyses demonstrated that the material property of cortical bone was the most significant model parameter. The computationally-modeled strains and strain gradients correlated significantly to the histologically-measured bone formation thickness at the mid-diaphyseal cross-section of the mouse tibia.
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    The fatigue responses of 3D-printed polylactic acid (PLA) parts with varying raster angles and printing speeds
    (John Wiley and Sons Inc, 2024) Horasan, Murat; Saraç, İsmail
    In this study, the fatigue behavior of FDM-3D printed polylactic acid (PLA) materials was investigated by rotary bending fatigue tests and finite element studies with varying printing speed and raster angle parameters. Fatigue test specimens were manufactured at five different raster angles (0°, 30°, 45°, 60°, and 90°) and two different printing speeds (20 and 80 mm/s). The effect of printing speed was evaluated at high print speed variation range (20 and 80 mm/s print speeds). It was noticed that the change in raster angle affects the fatigue life very significantly. The highest fatigue life was obtained at 30° raster angle, while the lowest fatigue life was found at 90° raster angle. Increasing the printing speed from 20 to 80 mm/s decreased the fatigue life of all specimens. The derived results from the finite element analyses were consistent with the experimental results.
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    The torsional characterization of 3D-Printed polylactic acid parts with alternating additive manufacturing parameters
    (John Wiley and Sons Ltd, 2024) Saraç, İsmail; Horasan, Murat
    Three-dimensional (3D) printed polymer parts can be subjected to torsional loads in accordance with the conditions of use. Understanding the torsional properties of 3D printed polymers depending on the printing parameters is a significant research topic in fused deposition modeling (FDM) additive manufacturing processes to be used as machine parts operating under torsional load, such as polymer parts manufactured by extrusion method. Some studies have shown that raster angle and printing speed affect the mechanical properties of 3D-printed polymers. However, tensile tests were used in most of those studies. In this study, the torsional behavior of 3D printed Polylactic acid (PLA) materials was investigated by static torsion tests, finite element analyses, and theoretical and failure analyses with respect to the printing speed and raster angle parameters. Torsion test specimens were manufactured at five different raster angles (0°, 30°, 45°, 60°, and 90°) and two different printing speeds (20 and 80 mm/s) from PLA material using the FDM additive manufacturing method. The results showed that raster angle and printing speed parameters affected the torsional load-carrying capacity of FDM-3D printed PLA parts. The best load-carrying capacity was achieved at 30° and 60° raster angles, while the lowest was measured at 0° raster angle. The torsional load-carrying capacity was significantly enhanced by 85% for specimens manufactured at the printing speed of 80 mm/s.